Sponsor Pipeline

BioNTech SE Clinical Trial Pipeline

Data updated daily from ClinicalTrials.gov — last refresh 2026-06-12
29
Active Trials
21
Recruiting
9
Phase 3
10
Disease Areas
8
Changes, 30 Days
What Changed in the Last 30 Days
DetectedTrialChange
2026-06-02 NCT06712355
Safety and Efficacy of BNT327, an Investigational Therapy in Combination With…
Trial sites expanded: 138 -> 202 locations
2026-05-23 NCT07070232
A Clinical Study to Test if an Investigational Treatment Called BNT326 is Safe and…
Trial sites expanded: 53 -> 64 locations
2026-05-23 NCT07173751
ROSETTA Breast-01: The Effects and Safety of Pumitamig in Patients With Triple-Negative…
Trial sites expanded: 83 -> 104 locations
2026-05-23 NCT06712316
Safety, Efficacy, and Pharmacokinetics of BNT327 in Combination With Chemotherapy and…
Trial sites expanded: 206 -> 225 locations
2026-05-21 NCT06340568
A Clinical Study of the Anti-cancer Effects of an Investigational Therapy or Chemotherapy…
Trial sites expanded: 132 -> 156 locations
2026-05-20 NCT06892548
A Clinical Study to Investigate the Efficacy and Safety of an Investigational Combination…
Trial sites expanded: 58 -> 76 locations
2026-05-15 NCT04486378
A Phase II Clinical Trial Comparing the Efficacy of RO7198457 Versus Watchful Waiting in…
overall status: "Recruiting" → "Active Not Recruiting"
2026-05-15 NCT04486378
A Phase II Clinical Trial Comparing the Efficacy of RO7198457 Versus Watchful Waiting in…
Trial sites reduced: 121 -> 90 locations
Active Trials by Phase
Phase 3
7
Phase 2/3
2
Phase 2
7
Phase 1/2
9
Phase 1
4
Active Trials — top 25 of 29
NCT IDTitleConditionStatus
Phase 3
NCT07365995 A Phase III Trial of BNT324 Versus Docetaxel in Metastatic Castration-resistant Prostate… Metastatic Castration-resistant Prostate Cancer Recruiting
NCT06340568 A Clinical Study of the Anti-cancer Effects of an Investigational Therapy or Chemotherapy… Endometrial Cancer Recruiting
NCT07173751 ROSETTA Breast-01: The Effects and Safety of Pumitamig in Patients With Triple-Negative… Breast Neoplasms Recruiting
NCT06712355 Safety and Efficacy of BNT327, an Investigational Therapy in Combination With… Extensive-stage Small-cell Lung Cancer Recruiting
NCT07222384 A Study to Learn About BNT162b2 (LP.8.1)-Adapted Vaccine Against SARS-CoV-2 in Children 5… COVID-19 Active, Not Recruiting
NCT05543616 A Study to Learn About Variant-Adapted COVID-19 RNA Vaccine Candidate(s) in Healthy… SARS-CoV-2 Virus Active, Not Recruiting
NCT07300839 A Study to Learn About a COVID-19 Vaccine in Healthy Adults 50 Through 64 Years of Age COVID-19 Active, Not Recruiting
Phase 2/3
NCT04534205 A Clinical Trial Investigating the Safety, Tolerability, and Therapeutic Effects of… Unresectable Head and Neck Squamous Cell Carcinoma Recruiting
NCT06712316 Safety, Efficacy, and Pharmacokinetics of BNT327 in Combination With Chemotherapy and… Non-small Cell Lung Cancer Recruiting
Phase 2
NCT07379580 A Randomized Clinical Trial Investigating the Safety, Reactogenicity, and Immunogenicity… Mpox (Monkeypox) Recruiting
NCT06841055 Safety and Preliminary Efficacy of Pumitamig (BNT327), an Investigational Therapy for… Non-small Cell Lung Cancer Recruiting
NCT07255404 A Clinical Trial Testing the Safety of BNT327 (an Investigational Drug) and How Well it… Pancreatic Ductal Adenocarcinoma (PDAC) Recruiting
NCT07297212 A Clinical Trial Testing the Safety of the Investigational Drug Pumitamig (BNT327) and… Recurrent Glioblastoma Recruiting
NCT06449222 Safety and Preliminary Effectiveness of BNT327, an Investigational Therapy for Breast… Locally Advanced Breast Cancer Active, Not Recruiting
NCT06449209 Safety, Preliminary Effectiveness of BNT327, an Investigational Therapy for Patients With… Extensive-stage Small-cell Lung Cancer Active, Not Recruiting
NCT04486378 A Phase II Clinical Trial Comparing the Efficacy of RO7198457 Versus Watchful Waiting in… Colorectal Cancer Stage II Active, Not Recruiting
Phase 1/2
NCT07147348 A First-in-human, Dose Escalation and Indication Expansion Study of BNT3212 as… Advanced Solid Tumor Recruiting
NCT07079631 A Clinical Study to Test if an Investigational Treatment Called BNT314 When Used in… Metastatic Colorectal Cancer Recruiting
NCT07111520 A Clinical Trial to Test if an Investigational Combination Therapy With BNT326 and BNT327… Non-small Cell Lung Cancer Recruiting
NCT07186842 A Clinical Trial to Test if the Investigational Drug BNT329 is Safe and Potentially… Advanced Solid Cancers Recruiting
NCT07455734 Early-phase Trial to Assess the Safety and Preliminary Efficacy of BNT3214 in Adults With… Advanced Solid Tumor Cancer Recruiting
NCT06827236 A Clinical Study to Find the Optimal Dose of an Investigational Treatment Called BNT323… Locally Advanced Breast Cancer Recruiting
NCT06892548 A Clinical Study to Investigate the Efficacy and Safety of an Investigational Combination… Advanced Lung Cancer Recruiting
NCT07070232 A Clinical Study to Test if an Investigational Treatment Called BNT326 is Safe and… Advanced Solid Tumor Recruiting
NCT05547464 Safety and Immune Responses After Vaccination With Two Investigational RNA-based Vaccines… Tuberculosis Active, Not Recruiting
View all 29 active BioNTech SE trials with filters →
Disease Areas
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