Xencor clinical trial pipeline

2 trials changed in the last 30 days: 0 stopped, 0 with notable changes, 2 with minor changes only.

1. Minor

   XmAb541 in Advanced Solid Tumors

   Trial sites expanded: 22 → 27 locations

   Xencor, Inc.·Phase 1· NCT06276491· Registry history of NCT06276491 on ClinicalTrials.gov (opens the registry)

   Updated Oct 9, 2026

2. Minor

   XmAb942 in Healthy Participants and · Ulcerative Colitis

   Trial sites expanded: 90 → 98 locations

   Also in this update: Completion pushed from Jan 2029 to May 2030; Primary completion moved earlier from Apr 2028 to Dec 2027

   Xencor, Inc.·Phase 1/2· NCT06619990· Registry history of NCT06619990 on ClinicalTrials.gov (opens the registry)

   Updated Sep 16, 2026

• Stopped: an ongoing trial was terminated, suspended or withdrawn.
• Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
• Minor: routine progress and housekeeping, such as sites added or enrollment closed.