St. Jude Children's Research Hospital clinical trial pipeline

7 trials changed in the last 30 days: 0 stopped, 5 with notable changes, 2 with minor changes only.

1. Notable

   Intensity-Modulated Proton Therapy for Incompletely Resected…Intensity-Modulated Proton Therapy for Incompletely Resected Craniopharyngioma and Observation for Craniopharyngioma After Radical Resection

   Primary completion pushed from Aug 2026 to Oct 2028

   St. Jude Children's Research Hospital·Phase 2· NCT02792582· Registry history of NCT02792582 on ClinicalTrials.gov (opens the registry)

   Sep 22, 2026

2. Notable

   CPX-351 (VYXEOS) in Individuals < 22 Years With Secondary…CPX-351 (VYXEOS) in Individuals < 22 Years With Secondary Myeloid Neoplasms

   Primary endpoint(s) modified

   Also in this update: Results posted: Oct 15, 2026

   St. Jude Children's Research Hospital·Phase 2· NCT05656248· Registry history of NCT05656248 on ClinicalTrials.gov (opens the registry)

   Oct 15, 2026

3. Notable

   Obesity Treatment With Phentermine-Topiramate ER in AYA Surviving…Obesity Treatment With Phentermine-Topiramate ER in AYA Surviving Leukemia and Lymphoma

   Primary endpoint(s) modified

   Also in this update: Enrollment increased: 45 → 100 participants

   St. Jude Children's Research Hospital·Phase 2· NCT07790913· Registry history of NCT07790913 on ClinicalTrials.gov (opens the registry)

   Sep 23, 2026

4. Notable

   Stem Cell Mobilization and Apheresis for Life-threatening Blood…Stem Cell Mobilization and Apheresis for Life-threatening Blood Disorders

   Recruitment opened

   St. Jude Children's Research Hospital·Phase 1· NCT07585136· Registry history of NCT07585136 on ClinicalTrials.gov (opens the registry)

   Oct 6, 2026

5. Notable

   Targeted Imaging to Characterize High-Risk Atherosclerotic…Targeted Imaging to Characterize High-Risk Atherosclerotic Cardiovascular Disease of Survivors in SJLIFE

   Recruitment opened

   Also in this update: Start date changed from estimate of Oct 2026 to Sep 21, 2026

   St. Jude Children's Research Hospital·Not specified· NCT07594392· Registry history of NCT07594392 on ClinicalTrials.gov (opens the registry)

   Sep 24, 2026

• Stopped: an ongoing trial was terminated, suspended or withdrawn.
• Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
• Minor: routine progress and housekeeping, such as sites added or enrollment closed.