Sponsor Pipeline

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins Clinical Trial Pipeline

Data updated daily from ClinicalTrials.gov — last refresh 2026-08-16
108
Active Trials
64
Recruiting
10
Disease Areas
18
Changes, 30 Days
What Changed in the Last 30 Days
DetectedTrialChange
2026-08-08 NCT03439735
Determinants of Resistance to Endocrine Therapy and a Cyclin-dependent Kinases 4 and 6…
date change Primary completion pushed: 2026-08-01 -> 2027-08-01
2026-08-08 NCT03439735
Determinants of Resistance to Endocrine Therapy and a Cyclin-dependent Kinases 4 and 6…
date change Completion pushed: 2026-11-01 -> 2027-11-01
2026-08-08 NCT07550517
PSMA-High: EBRT/ PSMA617/ ADT vs. EBRT/ ADT
date change Primary completion pushed: 2032-07 -> 2032-08
2026-08-08 NCT07550517
PSMA-High: EBRT/ PSMA617/ ADT vs. EBRT/ ADT
date change Completion pushed: 2033-07 -> 2033-08
2026-08-07 NCT05995821
Immunobiology Blood and Tissue Collection of Upper Aerodigestive Malignancies
date change Primary completion pushed: 2026-08-25 -> 2028-08-25
2026-08-07 NCT05995821
Immunobiology Blood and Tissue Collection of Upper Aerodigestive Malignancies
date change Completion pushed: 2026-08-25 -> 2028-08-25
2026-08-04 NCT05141513
Intraoperative Radiation Therapy After Stereotactic Body Radiation Therapy and…
Enrollment closed, study ongoing
2026-08-04 NCT05141513
Intraoperative Radiation Therapy After Stereotactic Body Radiation Therapy and…
Enrollment reduced: 25 -> 20 participants
2026-07-29 NCT07580339
Combining DCSZ11 With Radiation and Chemotherapy as Neoadjuvant Treatment for pMMR…
date change Primary completion pushed: 2030-07 -> 2030-10
2026-07-29 NCT07580339
Combining DCSZ11 With Radiation and Chemotherapy as Neoadjuvant Treatment for pMMR…
date change Completion pushed: 2030-07 -> 2030-10
2026-07-29 NCT05950139
Peptide Vaccine To Prevent Acquired Resistance In Patients With Advanced ALK+ NSCLC
date change Primary completion pushed: 2026-07 -> 2027-07
2026-07-29 NCT07140315
DK222 Study at Hopkins
date change Primary completion pushed: 2027-07-01 -> 2027-09-01
2026-07-29 NCT07140315
DK222 Study at Hopkins
date change Completion pushed: 2027-07-01 -> 2027-09-01
2026-07-28 NCT06411691
KRAS-Targeted Vaccine Combined With Balstilimab and Botensilimab for Patients With Stage…
date change Primary completion pushed: 2028-03-01 -> 2029-11-01
2026-07-28 NCT06411691
KRAS-Targeted Vaccine Combined With Balstilimab and Botensilimab for Patients With Stage…
date change Completion pushed: 2029-07-01 -> 2030-11-01
2026-07-25 NCT06014255
Trial of Neoadjuvant Enoblituzumab vs SOC in Men With High-Risk Localized Prostate Cancer
overall status: Recruiting → Active, Not Recruiting
2026-07-19 NCT04363164
Sequential Testosterone and Enzalutamide Prevents Unfavorable Progression
date change Primary completion pushed: 2026-07 -> 2027-07
2026-07-19 NCT04363164
Sequential Testosterone and Enzalutamide Prevents Unfavorable Progression
date change Completion pushed: 2027-07 -> 2028-07
Active Trials by Phase
Phase 2
46
Phase 1/2
7
Phase 1
22
Early Phase 1
4
Not specified
29
Active Trials — top 25 of 108
NCT IDTitleConditionStatus
Phase 2
NCT06245889 PET Dynamics to Response-Adapted Neoadjuvant Therapy in TNBC Triple Negative Breast Cancer Recruiting
NCT06617923 Study of Senaparib in Combination With Temozolomide in ARID1A Mutation Associated Ovarian… Ovary Cancer Recruiting
NCT04232085 Regenerative Medicine to Restore Hematopoiesis and Immune Function in Immunodeficiencies… Primary Immune Deficiency Disorder Recruiting
NCT06001658 Perioperative Gemcitabine, Cisplatin, and Pembrolizumab in Potentially Resectable Biliary… Billiary Track Cancer Recruiting
NCT05656235 Renal Retention in High Grade Upper Tract Urothelial Cancer High Grade Urothelial Carcinoma Recruiting
NCT06059118 Difluoromethylornithine and High Dose Testosterone With Enzalutamide in Metastatic… Prostate Cancer Recruiting
NCT04704505 Bipolar Androgen Therapy (BAT) and Radium-223 (RAD) in Metastatic Castration-resistant… Prostate Adenocarcinoma Recruiting
NCT06616597 Trial Targeting Gut Bacterial Androgen Production to Reverse Therapeutic Resistance to… Prostate Cancer (Adenocarcinoma) Recruiting
NCT04988074 Trial of Cemiplimab, or Cemip-Chemo Followed by Biomarker-guided Treatment for Pts w/HPV… HPV-Related Squamous Cell Carcinoma Recruiting
NCT05977907 Neoadjuvant Pembrolizumab and IO102-103 for Squamous Cell Carcinoma of the Head and Neck… Head and Neck Squamous Cell Carcinoma Recruiting
NCT07142551 Supraphysiologic Testosterone Priming Induces Darolutamide Extended Response Metastatic Castration-resistant Prostate Cancer Recruiting
NCT01804634 Reduced Intensity Haploidentical BMT for High Risk Solid Tumors Refractory and/or Relapsed Metastatic Solid Tumors Recruiting
NCT03786796 Study of Olaparib in Metastatic Renal Cell Carcinoma Patients With DNA Repair Gene… Renal Cell Carcinoma Recruiting
NCT06376669 Stereotactic Body Proton Therapy for Treatment of Primary Renal Cell Carcinoma Renal Cell Carcinoma Recruiting
NCT07209189 Neoadjuvant Chemotherapy and Programmed Cell Death Protein 1(PD-1) Inhibition for Head… Head and Neck Cancer Recruiting
NCT03521830 Nivolumab Alone or Plus Relatlimab or Ipilimumab for Patients With Locally-Advanced… Basal Cell Carcinoma Recruiting
NCT06941857 NC410 and FOLFIRINOX in Combination With Nivolumab With or Without Ipilimumab in Patients… Pancreatic Cancer Recruiting
NCT06205836 Cemiplimab With or Without Fianlimab to Treat Older Patients With Localized or Locally… Colorectal Cancer Recruiting
NCT06922318 The COSMYC Trial (COmbined Suppression of MYC) Metastatic Castration-resistant Prostate Cancer Recruiting
NCT05312671 Atezolizumab Plus Etoposide and Platinum in Small Cell Bladder Cancer Small Cell Neuroendocrine Carcinoma of Bladder Recruiting
NCT06210854 Assessing Administration of pBI-11 Via Electroporation for the Treatment of Patients With… HPV Infection Recruiting
NCT04363164 Sequential Testosterone and Enzalutamide Prevents Unfavorable Progression Castration Resistant Metastatic Prostate Cancer Recruiting
NCT07281768 Capecitabine/Oxaliplatin Chemotherapy and Cemiplimab With or Without Fianlimab or… Colorectal Cancer Recruiting
NCT02923180 Neoadjuvant Enoblituzumab (MGA271) in Men With Localized Intermediate and High-Risk… Prostate Cancer Active, Not Recruiting
NCT01088789 Boost GVAX Pancreas Vaccine With or Without CY in Patients With Pancreas Cancer Pancreatic Cancer Active, Not Recruiting
See all 108 active Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins trials with filters →
Disease Areas
Get alerts when Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins's trials change
Status changes, date slips, and new filings — detected daily, delivered to your inbox.
Start monitoring free