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Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins clinical trial pipeline

Get alerts when Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins's trials change

113 active trials 65 recruiting 33 disease areas 20 changes in 30 days

Data updated daily from ClinicalTrials.gov, last refresh 2026-10-02

What changed in the last 30 days

2026-09-30
Primary completion pushed: 2027-09-01 → 2028-01-31
Completion pushed: 2027-09-01 → 2028-01-31
NCT07140315 DK222 Study at Hopkins · Phase 1
2026-09-25
Primary completion pushed: 2026-09-30 → 2026-12-30
Completion pushed: 2026-12-30 → 2027-03-30
NCT03573648 Neoadjuvant Endocrine Therapy, Palbociclib, Avelumab in Estrogen Receptor Positive Breast… · Phase 2
2026-09-25
Primary completion pushed: 2026-09 → 2027-09
Completion pushed: 2027-03 → 2028-03
NCT06398457 Darzalex Faspro (Daratumumab and Hyaluronidase-fihj) Before Standard Desensitization and… · Early Phase 1
2026-09-09
Primary completion pushed: 2026-09-02 → 2027-03-02
Completion pushed: 2027-07-01 → 2027-09-01
NCT03875287 Dose-Escalation Study of E7727, an Oral Cytidine Deaminase Inhibitor With Oral Decitabine… · Phase 1
2026-09-04
Primary completion pushed: 2026-09-01 → 2027-08-01
NCT05386719 Cardiometabolic Screening Program
2026-09-04
Primary completion pushed: 2026-09 → 2027-09
Completion pushed: 2027-01 → 2028-01
NCT06138067 Patient Navigation Program to Improve Clinical Trial Enrollment in Cancer Patients
2026-09-05
Primary endpoint(s) modified
Enrollment reduced: 30 → 20 participants
Recruitment opened
Primary completion moved earlier: 2031-02-01 → 2031-01-01
Completion moved earlier: 2031-02-01 → 2031-01-01
NCT07360119 Total Pancreatectomy With Islet Autotransplantation (TPIAT) for High-Risk Patients With…
2026-09-23
Enrollment closed, study ongoing
NCT05977907 Neoadjuvant Pembrolizumab and IO102-103 for Squamous Cell Carcinoma of the Head and Neck… · Phase 2
2026-09-23
Recruitment opened
NCT07550517 PSMA-High: EBRT/ PSMA617/ ADT vs. EBRT/ ADT · Phase 2
2026-09-17
Results posted: 2026-09-16
NCT03377517 Radiosurgical Hypophysectomy for Bone Metasteses Pain
2026-09-19
Primary completion confirmed: July 2025 (last estimated July 2026)
NCT05141513 Intraoperative Radiation Therapy After Stereotactic Body Radiation Therapy and… · Phase 1

New trial filings, last 30 days

First postedTrialPhaseStatus
2026-10-01 NCT07852975 GLAD-KE GLioma Biomarker and Safety Assessment During Dietary Ketone Elevation Subtitle… Not Yet Recruiting
2026-09-23 NCT07836101 Study of Sarilumab With Immune Checkpoint Inhibitor Rechallenge in Patients With… Phase 2 Not Yet Recruiting

Active trials by phase

Early Phase 1
5
Phase 1
22
Phase 1/2
7
Phase 2
48
Not charted: 31 active trials with no phase listed on ClinicalTrials.gov (typically behavioural, device, procedure and observational studies).

Active trials top 25 of 113

NCT IDTitleConditionStatusUpdated
Phase 2
NCT07550517 PSMA-High: EBRT/ PSMA617/ ADT vs. EBRT/ ADT High-Risk Localized Prostate Cancer Recruiting 2026-09-22
NCT06245889 PET Dynamics to Response-Adapted Neoadjuvant Therapy in TNBC Triple Negative Breast Cancer Recruiting 2026-09-03
NCT07281768 Capecitabine/Oxaliplatin Chemotherapy and Cemiplimab With or Without Fianlimab or… Colorectal Cancer Recruiting 2026-07-21
NCT04363164 Sequential Testosterone and Enzalutamide Prevents Unfavorable Progression Castration Resistant Metastatic Prostate Cancer Recruiting 2026-07-17
NCT06210854 Assessing Administration of pBI-11 Via Electroporation for the Treatment of Patients With… HPV Infection Recruiting 2026-07-01
NCT05312671 Atezolizumab Plus Etoposide and Platinum in Small Cell Bladder Cancer Small Cell Neuroendocrine Carcinoma of Bladder Recruiting 2026-06-25
NCT06922318 The COSMYC Trial (COmbined Suppression of MYC) Metastatic Castration-resistant Prostate Cancer Recruiting 2026-06-18
NCT06205836 Cemiplimab With or Without Fianlimab to Treat Older Patients With Localized or Locally… Colorectal Cancer Recruiting 2026-05-06
NCT06941857 NC410 and FOLFIRINOX in Combination With Nivolumab With or Without Ipilimumab in Patients… Pancreatic Cancer Recruiting 2026-05-05
NCT03521830 Nivolumab Alone or Plus Relatlimab or Ipilimumab for Patients With Locally-Advanced… Basal Cell Carcinoma Recruiting 2026-04-29
NCT07209189 Neoadjuvant Chemotherapy and Programmed Cell Death Protein 1(PD-1) Inhibition for Head… Head and Neck Cancer Recruiting 2026-04-23
NCT06376669 Stereotactic Body Proton Therapy for Treatment of Primary Renal Cell Carcinoma Renal Cell Carcinoma Recruiting 2026-04-03
NCT03786796 Study of Olaparib in Metastatic Renal Cell Carcinoma Patients With DNA Repair Gene… Renal Cell Carcinoma Recruiting 2026-03-30
NCT01804634 Reduced Intensity Haploidentical BMT for High Risk Solid Tumors Refractory and/or Relapsed Metastatic Solid Tumors Recruiting 2026-03-13
NCT07142551 Supraphysiologic Testosterone Priming Induces Darolutamide Extended Response Metastatic Castration-resistant Prostate Cancer Recruiting 2026-03-11
NCT04988074 Trial of Cemiplimab, or Cemip-Chemo Followed by Biomarker-guided Treatment for Pts w/HPV… HPV-Related Squamous Cell Carcinoma Recruiting 2026-03-03
NCT06616597 Trial Targeting Gut Bacterial Androgen Production to Reverse Therapeutic Resistance to… Prostate Cancer (Adenocarcinoma) Recruiting 2026-02-19
NCT04704505 Bipolar Androgen Therapy (BAT) and Radium-223 (RAD) in Metastatic Castration-resistant… Prostate Adenocarcinoma Recruiting 2026-02-06
NCT06059118 Difluoromethylornithine and High Dose Testosterone With Enzalutamide in Metastatic… Prostate Cancer Recruiting 2026-01-14
NCT05656235 Renal Retention in High Grade Upper Tract Urothelial Cancer High Grade Urothelial Carcinoma Recruiting 2026-01-08
NCT06001658 Perioperative Gemcitabine, Cisplatin, and Pembrolizumab in Potentially Resectable Biliary… Billiary Track Cancer Recruiting 2025-12-03
NCT04232085 Regenerative Medicine to Restore Hematopoiesis and Immune Function in Immunodeficiencies… Primary Immune Deficiency Disorder Recruiting 2025-11-28
NCT06617923 Study of Senaparib in Combination With Temozolomide in ARID1A Mutation Associated Ovarian… Ovary Cancer Recruiting 2025-10-27
NCT05081193 Safety and Efficacy of Oral Testosterone Undecanoate Followed by Enzalutamide as Therapy… Prostate Cancer Active, Not Recruiting 2026-09-29
NCT03573648 Neoadjuvant Endocrine Therapy, Palbociclib, Avelumab in Estrogen Receptor Positive Breast… Breast Cancer Active, Not Recruiting 2026-09-24
See all 113 active Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins trials with filters →

Disease areas by active trials, top 10 of 33

Prostate Cancer (19) · Breast Cancer (11) · Pancreatic Cancer (10) · Bladder Cancer (7) · Glioblastoma (6) · Colorectal Cancer (5) · Head & Neck Cancer (5) · Leukemia (5) · Sarcoma (5) · Kidney Cancer (4)

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