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Shanghai Henlius Biotech clinical trial pipeline

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56 active trials 27 recruiting 13 Phase 3 19 disease areas 1 changes in 30 days

Data updated daily from ClinicalTrials.gov, last refresh 2026-10-02

What changed in the last 30 days

2026-09-25
minor
NCT07477587 A Study to Compare the PK Characteristics, Safety, Tolerability, and Immunogenicity of… · Phase 1

New trial filings, last 30 days

First postedTrialPhaseStatus
2026-09-17 NCT07824869 A Phase II Study of HLX22 in Combination With Trastuzumab and Chemotherapy in… Phase 2 Not Yet Recruiting

Active trials by phase

Early Phase 1
1
Phase 1
19
Phase 1/2
2
Phase 2
21
Phase 2/3
5
Phase 3
8

Active trials top 25 of 56

NCT IDTitleConditionStatusUpdated
Phase 3
NCT06532006 A Phase Ⅲ Clinical Study of HLX22 in Combination With Trastuzumab and Chemotherapy for… Gastroesophageal-junction Cancer Recruiting 2026-02-27
NCT05353257 A Study to Evaluate the Efficacy and Safety of Serplulimab in Combination With… Limited-Stage Small Cell Lung Cancer Active, Not Recruiting 2026-01-13
NCT05468489 To Evaluate Efficacy and Safety of Serplulimab + Chemotherapy (Carboplatin- Etoposide) in… Extensive Stage Small Cell Lung Cancer Active, Not Recruiting 2025-10-21
NCT05346224 A Study to Evaluate the Efficacy and Safety of HLX11 vs. EU-Perjeta® in the Neoadjuvant… Breast Cancer Active, Not Recruiting 2025-06-10
NCT06895512 A Study to Evaluate the Efficacy and Safety of HLX15-IV Versus DARZALEX® in Combination… Newly Diagnosed Multiple Myeloma Not Yet Recruiting 2025-03-26
NCT06847334 A Study to Compare the Efficacy, Safety, Immunogenicity, and Pharmacokinetic Profile of… Non-Squamous Non-Small Cell Lung Cancer Not Yet Recruiting 2025-02-26
NCT06841185 A Study to Compare the Efficacy, Safety, Immunogenicity, and Pharmacokinetic Profile of… Hepatocellular Carcinoma (HCC) Not Yet Recruiting 2025-02-24
NCT04301739 to Evaluate Efficacy and Safety of HLX10 in Combination With Chemotherapy Versus Placebo… Triple Negative Breast Cancer Not Yet Recruiting 2020-03-12
Phase 2/3
NCT07459751 A Global Phase II/III Clinical Study to Evaluate the Efficacy and Safety of HLX43… Advanced or Metastatic Squamous Non-Small Cell Lung Cancer Recruiting 2026-06-01
NCT07294508 A Study to Evaluate HLX22 in Combination With HLX87 in Patients With HER2-Positive… HER2 + Breast Cancer Recruiting 2026-03-20
NCT04547166 A Clinical Study to Evaluate Efficacy and Safety of Serplulimab(HLX10) Combined With… Metastatic Colorectal Cancer Recruiting 2024-10-17
NCT07318883 A Phase II/III Clinical Study to Evaluate HLX07 in Combination With Serplulimab and… Squamous NSCLC Not Yet Recruiting 2026-01-06
NCT07294534 A Phase II/III Clinical Study to Evaluate the Efficacy and Safety of HLX87in Combination… HER2 + Breast Cancer Not Yet Recruiting 2025-12-19
Phase 2
NCT06907615 A Phase II Clinical Study to Evaluate HLX43 in Subjects With Advanced Non-small Cell Lung… Non Small Cell Lung Cancer Recruiting 2026-10-01
NCT07253142 A Phase II Clinical Study to Evaluate HLX43 in Combination With Serplulimab in Subjects… Non Small Cell Lung Cancer Recruiting 2026-07-21
NCT07269782 A Phase II Study to Evaluate the Efficacy and Safety of HLX43 + Serplulimab as… Non Small Cell Lung Cancer Recruiting 2026-06-04
NCT06769113 A Phase II Clinical Study to Evaluate HLX43 in Patients With Recurrent/Metastatic ESCC… Esophageal Cancer Recruiting 2026-05-18
NCT06769152 A Phase II Clinical Study to Evaluate the Efficacy and Safety of HLX43 (Anti-PD-L1 ADC)… Cervical Cancer Recruiting 2026-04-22
NCT06857279 A Phase II Clinical Study to Evaluate HLX43 in Subjects With Recurrent or Metastatic Head… Carcinoma of Head and/or Neck Recruiting 2026-03-05
NCT06839066 A Phase II Study to Evaluate HLX43 in Subjects With Recurrent/Metastatic Nasopharyngeal… Nasopharyngeal Carcinoma (NPC) Recruiting 2025-11-24
NCT07038382 A Study to Evaluate the Efficacy, Safety, and Tolerability of Human Sialidase Fusion… Membranous Nephropathy Recruiting 2025-11-18
NCT07115485 Phase II, Open-label, Multicenter Study to Evaluate the Efficacy and Safety of HLX43 (an… Gastric or Gastroesophageal Junction Adenocarcinoma Recruiting 2025-11-18
NCT07106892 Phase II, Open-label, Multicenter Study to Evaluate the Efficacy and Safety of HLX43 (an… Colorectal Cancer (CRC) Recruiting 2025-11-17
NCT06832202 A Phase II Study of HLX22 in Combination With Trastuzumab Deruxtecan in HER2-low, Hormone… HER2-low Hormone Receptor Positive Breast Cancer Recruiting 2025-06-15
NCT06742892 A Phase II Clinical Study to Evaluate HLX43 in Patients With Locally Advanced or… Carcinoma, Hepatocellular Recruiting 2025-03-10

Disease areas by active trials, top 10 of 19

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