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Pfizer clinical trial pipeline

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252 active trials 120 recruiting 90 Phase 3 51 disease areas 133 changes in 30 days

Data updated daily from ClinicalTrials.gov, last refresh 2026-10-02

What changed in the last 30 days showing 48 of 133 changes on 20 trials

2026-09-16
Reclassified as terminated (was completed)
Trial terminated: Study discontinued due to questions of data validity and bias in data which would limit causal inference and estimation...
NCT05876377 Use and Effectiveness of COVID-19 Vaccines Using State Vaccine Registries and Insurance…
2026-09-15
Withdrawn before enrolling
Trial withdrawn: Withdrawal of the marketing authorization for the breast cancer indication of Talzenna® in Korea, not related to safety...
NCT04982848 Korea Post Marketing Surveillance (PMS) Study of Talzenna®
2026-09-29
Primary completion pushed: 2031-07-22 → 2032-01-15
Trial sites expanded: 74 → 100 locations
Completion pushed: 2032-07-21 → 2033-01-14
NCT07392892 Symbiotic-GI-16: A Study to Learn About the Study Medicine Called PF-08634404 in… · Phase 2/3
2026-09-24
Primary completion pushed: 2026-12-28 → 2029-10-25
Completion pushed: 2026-12-28 → 2029-10-25
NCT05144997 Lorlatinib Continuation Study · Phase 4
2026-09-16
Primary completion pushed: 2027-07-28 → 2030-07-29
Trial sites reduced: 146 → 138 locations
Completion pushed: 2027-07-28 → 2030-07-29
NCT05895786 A Study to Understand How the Study Medicine (PF-06823859) Works in People With Active… · Phase 3
2026-09-04
Primary completion pushed: 2026-01-12 → 2026-10-30
Trial sites expanded: 143 → 151 locations
Completion pushed: 2026-08-31 → 2026-10-30
NCT04657991 A Clinical Trial of Three Study Medicines (Encorafenib, Binimetinib, and Pembrolizumab)… · Phase 3
2026-09-15
Primary completion pushed: 2026-08-23 → 2027-02-26
Enrollment increased: 192 → 235 participants
Trial sites reduced: 51 → 44 locations
Completion pushed: 2026-08-23 → 2027-02-26
NCT05262400 A Study to Learn About the Study Medicine (Called PF-07220060 in Combination With… · Phase 1/2
2026-09-10
Primary completion pushed: 2026-12-31 → 2029-12-31
Completion pushed: 2026-12-31 → 2029-12-31
NCT05226871 Study for Participants Continuing From Pfizer-sponsored Palbociclib (a Study Medicine)… · Phase 2
2026-09-03
Primary completion pushed: 2026-09-01 → 2027-03-24
Completion pushed: 2026-09-01 → 2027-03-24
NCT05548127 TACTIVE-U: A Study to Learn About the Study Medicine (Vepdegestrant) When Given With… · Phase 1/2
2026-09-22
Primary completion pushed: 2026-07-31 → 2026-10-31
Completion pushed: 2026-07-31 → 2026-10-31
NCT06898047 Consistency of Response With Rimegepant in Acute Treatment of Migraine
2026-09-16
Primary completion pushed: 2027-04-10 → 2027-11-16
Enrollment closed, study ongoing
Final enrollment: 100 participants (planned 87)
Completion pushed: 2028-03-09 → 2028-10-15
NCT06215118 A Study to Learn About the Effects of the Combination of Elranatamab (PF-06863135) and… · Phase 1
2026-09-09
Primary completion pushed: 2028-02-02 → 2028-05-05
Completion pushed: 2029-03-29 → 2029-07-01
NCT07663630 A Study to Learn About the Study Medicine Called Ponsegromab in Adults With Lung… · Phase 1
2026-09-18
Primary completion pushed: 2026-07-31 → 2027-03-01
Completion pushed: 2026-07-31 → 2027-03-01
NCT07567352 A Study to Learn About Patients With Non-Small Cell Lung Cancer (NSCLC) Who Took…
2026-09-30
Primary endpoint(s) modified
Results posted: 2026-09-29
NCT05132582 A Study of Tucatinib or Placebo With Trastuzumab and Pertuzumab for Metastatic HER2+… · Phase 3
2026-10-01
Primary endpoint(s) modified
Results posted: 2026-09-30
Completion pushed: 2026-09-07 → 2027-05-25
NCT06206837 A Study to Learn About Vepdegestrant When Given With PF-07220060 to People With Advanced… · Phase 1/2
2026-10-02
Primary endpoint(s) modified
Interventions modified
Trial arms changed: 3 → 8
NCT07090499 A Study to Learn About the Study Medicine Called PF-08046876 in People With Advanced… · Phase 1
2026-09-16
Primary endpoint(s) modified
NCT06507904 A Study to Learn How Different Preparations of Osivelotor Taste and Enter the Blood With… · Phase 1
2026-09-19
Enrollment reduced: 1330 → 674 participants
NCT06873945 A Study of 2 Doses of Ritlecitinib in People 12 Years of Age and Older With Alopecia… · Phase 3
2026-09-30
Recruitment opened
Trial sites expanded: 0 → 3 locations
Primary completion moved earlier: 2028-06-19 → 2028-04-30
Trial started: 2026-09-17 (last estimated 2026-09-19)
NCT07823608 A Study to Learn About the Monthly Dosing Study Medicine Called Berobenatide in Adults… · Phase 3
2026-10-02
Trial completed
NCT07597928 A Study to Learn How Different Forms of the Study Medicine Called PF-08049820 Are… · Phase 1

New trial filings, last 30 days

First postedTrialPhaseStatus
2026-09-29 NCT07845500 A Study to Learn About Switching to a Monthly Study Medicine Called Berobenatide… Phase 3 Not Yet Recruiting
2026-09-29 NCT07845513 A Study to Learn About the Study Medicine Called PF-08653944 in Otherwise Healthy Chinese… Phase 1 Not Yet Recruiting
2026-09-24 NCT07839871 Study to Learn About a Respiratory Syncytial Virus Vaccine in Children at High Risk of… Phase 3 Not Yet Recruiting
2026-09-24 NCT07839884 A Continuation Study of Tilrekimig in Adults With Moderate-to-Severe Long-Term Breathing… Phase 3 Not Yet Recruiting
2026-09-16 NCT07823595 Abrocitinib Treatment of Atopic Dermatitis in Children 2 to Less Than 6 Years of Age Phase 3 Not Yet Recruiting
2026-09-16 NCT07823608 A Study to Learn About the Monthly Dosing Study Medicine Called Berobenatide in Adults… Phase 3 Recruiting
2026-09-15 NCT07821216 Real-World Effectiveness of Ritlecitinib in Alopecia Areata Patients in the US: A… Active, Not Recruiting
2026-09-14 NCT07819097 A Study to Learn About the Safety and Immune Responses of RSVpreF in Older Adults Phase 3 Not Yet Recruiting

Active trials by phase

Phase 1
42
Phase 1/2
13
Phase 2
34
Phase 2/3
5
Phase 3
85
Phase 4
9
Not charted: 64 active trials with no phase listed on ClinicalTrials.gov (typically behavioural, device, procedure and observational studies).

Active trials top 25 of 252

NCT IDTitleConditionStatusUpdated
Phase 4
NCT06952660 Ocular Assessments in Patients Treated With Tivdak® in Recurrent or Metastatic Cervical… Cervical Cancer Recruiting 2026-09-25
NCT07609914 A Study to Learn About the Safety of Taking an Additional Dose of the Medicine Rimegepant… Acute Treatment of Migraine Recruiting 2026-09-25
NCT07685769 A Study to Find Out if the Medicine Called Rimegepant is Safe for Adults in India Acute Treatment of Migraine Recruiting 2026-09-24
NCT06057402 Elranatamab Post Trial Access Study for Participants With Multiple Myeloma (MM) Multiple Myeloma Recruiting 2026-07-01
NCT05203172 The FLOTILLA Study: Providing Continued Access to The Study Medicines Encorafenib and… Solid Tumors Recruiting 2026-04-07
NCT05144997 Lorlatinib Continuation Study Non-Small-Cell Lung Cancer Active, Not Recruiting 2026-09-23
NCT07768358 Tucatinib Continuation Study HER2-positive Breast Cancer Not Yet Recruiting 2026-08-28
NCT05295290 A Study to Learn About The COVID-19 (Study) Vaccine (Called COMIRNATY) in People That Are… Myocarditis Active, Not Recruiting 2026-05-07
NCT05160922 Crizotinib Continuation Clinical Study NSCLC Active, Not Recruiting 2026-03-30
Phase 3
NCT07823608 A Study to Learn About the Monthly Dosing Study Medicine Called Berobenatide in Adults… Apnea Recruiting 2026-09-29
NCT05156398 Efficacy and Safety Study of Rimegepant for the Preventative Treatment of Migraine in… Migraine Recruiting 2026-09-28
NCT07144280 A Study to Learn About the Study Medicine Called PF-08046054/SGN-PDL1V Versus Docetaxel… Non-small Cell Carcinoma Recruiting 2026-09-28
NCT07222800 Symbiotic-GI-03: A Study to Learn About the Study Medicine Called PF-08634404 in… Intestinal Neoplasms Recruiting 2026-09-28
NCT07595549 A Study to Learn About the Study Medicine Called Berobenatide (PF-08653944) in People… Obesity Recruiting 2026-09-28
NCT05623020 A Study to Learn About the Effects of the Combination of Elranatamab, Daratumumab and… Multiple Myeloma Recruiting 2026-09-25
NCT06629779 A Study to Learn How PF-06821497 (Mevrometostat) Works in Men With Metastatic… Metastatic Castration-Resistant Prostate Cancer Recruiting 2026-09-25
NCT06679140 A Study to Learn About a Study Medicine Called Ibuzatrelvir in Adult and Adolescent… COVID-19 SARS-CoV-2 Infection Recruiting 2026-09-25
NCT06758401 This is a Study to Learn About How the Combination of the Study Medicines Sigvotatug… Non-Small Cell Lung Cancer Recruiting 2026-09-25
NCT06807268 A Study of the Medicine Called Abrocitinib in Children 6 to Less Than 12 Years of Age… Eczema Recruiting 2026-09-25
NCT06807281 A Long-term Study of the Medicine Called Abrocitinib in Children Aged 2 Years and Older… Atopic Dermatitis Recruiting 2026-09-25
NCT07013474 A Study to Learn About the Study Medicine Ibuzatrelvir in Adults With COVID-19 Who Are… COVID-19 Infection Recruiting 2026-09-25
NCT07160244 BEATRIX: A Study to Learn About a Group B Streptococcus Vaccine in Healthy Pregnant Women… Healthy Recruiting 2026-09-25
NCT07222566 Symbiotic-Lung-01 : A Study to Learn About the Study Medicine Called PF-08634404 in… Advanced Non-Small Cell Lung Cancer Recruiting 2026-09-25
NCT07729462 A Study to Learn About the Study Medicine Called Rimegepant in Adults When Used for the… Preventive Treatment of Migraine Recruiting 2026-09-25
NCT07768345 A Study to Learn About Revaccination With a Vaccine Called RSVpreF in Immunocompromised… Respiratory Syncytial Virus (RSV) Recruiting 2026-09-25
See all 252 active Pfizer trials with filters →

Disease areas by active trials, top 10 of 51

Breast Cancer (31) · Lung Cancer (30) · Non-Small Cell Lung Cancer (NSCLC) (29) · Obesity (15) · Atopic Dermatitis (13) · Migraine (13) · Colorectal Cancer (11) · Multiple Myeloma (11) · Prostate Cancer (10) · Bladder Cancer (9)

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