Sponsor pipeline

Nationwide Children's Hospital clinical trial pipeline

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Data updated daily from ClinicalTrials.gov, last refresh 2026-10-16

What changed in the last 30 days

1 trial changed in the last 30 days: 0 stopped, 0 with notable changes, 1 with a minor change only.

  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.

Active trials by phase

Early Phase 1
3
Phase 1
2
Phase 1/2
7
Phase 2
10
Phase 2/3
1
Phase 3
1
Not charted: 27 active trials with no phase listed on ClinicalTrials.gov (typically behavioural, device, procedure and observational studies).

Active trials top 25 of 51

NCT IDTitleConditionStatusUpdated
Phase 3
NCT07291102 Comparison of Neurocognitive Outcome in Two Standard Regimen for Treatment of Low-risk… Medulloblastoma Not Yet Recruiting 2025-12-18
Phase 2/3
NCT05267821 Targeted Reversal of Inflammation in Pediatric Sepsis-induced MODS Pediatric Sepsis-induced Multiple Organ Dysfunction Syndrome (MODS) Recruiting 2026-03-13
Phase 2
NCT06838676 ACT001 for the Treatment of Diffuse Intrinsic Pontine Gliomas and H3K27-altered High… Diffuse Intrinsic Pontine Gliomas (DIPG) Recruiting 2026-09-21
NCT05096481 PEP-CMV Vaccine Targeting CMV Antigen to Treat Newly Diagnosed Pediatric HGG and DIPG and… High Grade Glioma Recruiting 2026-08-24
NCT05843253 Study of Ribociclib and Everolimus in HGG and DIPG or Ribociclib and Temozolomide in DHG… High Grade Glioma Recruiting 2026-05-29
NCT05233397 ACTEMRA® for the Treatment of Pediatric Adamantinomatous Craniopharyngioma Adamantinomatous Craniopharyngioma Recruiting 2026-04-23
NCT05286788 MEKTOVI® for the Treatment of Pediatric Adamantinomatous Craniopharyngioma Adamantinous Craniopharyngioma Recruiting 2026-04-08
NCT05135975 A Study of Cabozantinib as a Maintenance Agent to Prevent Progression or Recurrence in… Neuroblastoma Recruiting 2025-08-12
NCT04467671 Two-Year Study of the Safety and Efficacy of the Second-Generation Tissue Engineered… HLH - Hypoplastic Left Heart Syndrome Recruiting 2025-06-27
NCT07644312 Study of Relatlimab and Nivolumab (Opdualag) in Replication Repair Deficient HGG and DIPG High Grade Glioma Not Yet Recruiting 2026-09-09
NCT07206849 Study of Tovorafenib in High-Grade Glioma and Diffuse Intrinsic Pontine Glioma (DIPG) High Grade Glioma (HGG) of the Brain With BRAF Aberration Not Yet Recruiting 2026-07-31
NCT02378428 MIBG Therapy for Patients With MIBG Avid Tumors MIBG Avid Tumors Active, Not Recruiting 2025-05-13
Phase 1/2
NCT05278208 Lutathera for Treatment of Recurrent or Progressive High-Grade CNS Tumors High Grade Glioma Recruiting 2026-07-20
NCT05634369 A Multi-Institution Study of TGFβ Imprinted, Ex Vivo Expanded Universal Donor NK Cell… Pediatric Sarcoma, Refractory Recruiting 2026-01-28
NCT04722029 Pilot Study of Haploidentical Donor Adenovirus Specific T-lymphocytes to Treat Refractory… Adenovirus Infection Recruiting 2025-05-13
NCT05503134 Safety and Efficacy of Expanded, Universal Donor Natural Killer Cells for… Acute Myeloid Leukemia Recruiting 2024-11-04
NCT04211675 NK Cells Infusions With Irinotecan, Temozolomide, and Dinutuximab Relapsed Neuroblastoma Active, Not Recruiting 2026-09-16
NCT03431090 Haploidentical Hematopoietic Cell Transplantation for Children With Hematologic… Myelodysplasia Active, Not Recruiting 2026-04-03
NCT07026942 Phase I/II Clinical Trial of Universal Donor CD33 CAR Natural Killer Cells for AML Relapsed/Refractory AML Not Yet Recruiting 2025-11-12
Phase 1
NCT04254419 Phase 1 Study of Locoregional Injections of Ex Vivo Expanded Natural Killer Cells High Grade Glioma Recruiting 2025-05-13
NCT03605550 A Phase 1b Study of PTC596 in Children With Newly Diagnosed Diffuse Intrinsic Pontine… High Grade Glioma Active, Not Recruiting 2026-03-27
Early Phase 1
NCT06333899 Lorlatinib for Newly-Diagnosed High-Grade Glioma With ROS or ALK Fusion High Grade Glioma Recruiting 2026-06-29
NCT04655404 A Pilot Study of Larotrectinib for Newly-Diagnosed High-Grade Glioma With NTRK Fusion High Grade Glioma Recruiting 2026-03-18
NCT05779930 Safety and Feasibility of CD19 CAR T Cells Using CliniMACS Prodigy for… Acute Lymphoblastic Leukemia, in Relapse Not Yet Recruiting 2025-08-15
Not applicable
NCT07798180 Transauricular Neurostimulation for Abdominal Pain Due to DGBI Abdominal Pain (AP) Recruiting 2026-09-01

Disease areas by active trials, top 10 of 14

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