| Detected | Trial | Change |
|---|---|---|
| 2026-08-01 | NCT06299410 PET Study to Evaluate Brain Receptor Occupancy, Safety and Pharmacokinetics of ITI-1284… |
date change Completion moved earlier: 2026-10-30 -> 2026-08-19 |
| 2026-07-25 | NCT06462586 Study of Lumateperone in the Acute Treatment of Patients With Bipolar Mania |
Trial completed |
| 2026-07-25 | NCT06557902 Safety, Tolerability and Pharmacokinetics of Lumateperone in Pediatric Patients With… |
Trial completed |
| 2026-07-25 | NCT06557902 Safety, Tolerability and Pharmacokinetics of Lumateperone in Pediatric Patients With… |
Enrollment increased: 26 -> 33 participants |
| 2026-07-25 | NCT06557902 Safety, Tolerability and Pharmacokinetics of Lumateperone in Pediatric Patients With… |
date change Primary completion moved earlier: 2026-07-31 -> 2025-11-26 |
| 2026-07-25 | NCT06557902 Safety, Tolerability and Pharmacokinetics of Lumateperone in Pediatric Patients With… |
date change Completion moved earlier: 2026-07-31 -> 2025-11-26 |
| 2026-07-25 | NCT06462612 Study of Lumateperone in the Treatment of Patients With Bipolar Mania |
Trial completed |
| First Posted | Trial | Phase | Status |
|---|---|---|---|
| 2026-08-05 | NCT07747389 A Study of Lumateperone Versus Placebo in Participants With Major Depressive Disorder | Phase 3 | Not Yet Recruiting |
| NCT ID | Title | Condition | Status |
|---|---|---|---|
| Phase 3 | |||
| NCT05850689 | Study of Lumateperone as Adjunctive Therapy in the Treatment of Patients With Major… | Major Depressive Disorder | Recruiting |
| NCT06372964 | Multicenter Study of Lumateperone for the Treatment of Bipolar Depression in Pediatric… | Bipolar Depression | Recruiting |
| NCT06690398 | Multicenter Study of Lumateperone for the Treatment of Irritability Associated With… | Irritability Associated With Autism Spectrum Disorder | Recruiting |
| NCT06706674 | Multicenter Study of Lumateperone for the Treatment of Irritability Associated With… | Irritability Associated With Autism Spectrum Disorder | Recruiting |
| NCT06229210 | Safety and Tolerability Trial of Lumateperone in Pediatric Patients With Schizophrenia… | Schizophrenia | Recruiting |
| NCT07747389 | A Study of Lumateperone Versus Placebo in Participants With Major Depressive Disorder | Depressive Disorder, Major | Not Yet Recruiting |
| Phase 2 | |||
| NCT06480383 | Study of ITI-1284 as an Adjunctive Treatment in Patients With Generalized Anxiety Disorder | Generalized Anxiety Disorder | Recruiting |
| NCT06701903 | Study of ITI-1284 as Monotherapy Treatment in Patients With Generalized Anxiety Disorder | Generalized Anxiety Disorder | Recruiting |
| NCT06540833 | A Study to Assess the Efficacy and Safety of ITI-1284 in the Treatment of Psychosis… | Psychosis Associated With Alzheimer's Disease | Recruiting |
| NCT06651567 | A Study to Assess the Efficacy and Safety of ITI-1284 in the Treatment of Agitation… | Agitation Associated With Alzheimer's Dementia | Recruiting |
| Phase 1 | |||
| NCT06299410 | PET Study to Evaluate Brain Receptor Occupancy, Safety and Pharmacokinetics of ITI-1284… | Healthy Volunteers | Recruiting |