Sponsor pipeline

InSightec clinical trial pipeline

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23 active trials 9 recruiting 7 disease areas

Data updated daily from ClinicalTrials.gov, last refresh 2026-08-28

What changed in the last 30 days

First postedNew trial filingPhaseStatus
2026-08-14 NCT07764874 Unilateral and Staged Bilateral Pallidothalamic Tractotomy Using Exablate MRgFUS in… Not Yet Recruiting

Active trials by phase

Phase 1/2
2
Phase 3
1
Not charted: 20 active trials with no phase listed on ClinicalTrials.gov (typically behavioural, device, procedure and observational studies).

Active trials

NCT IDTitleConditionStatusUpdated
Phase 3
NCT05317858 Blood-brain Barrier (BBB) Opening Using Exablate Focused Ultrasound With Standard of Care… Brain Tumor Recruiting 2026-08-19
Phase 1/2
NCT05615623 Blood Brain Barrier (BBB) Disruption Using Exablate Focused Ultrasound With Doxorubicin… Brain Tumor Active, Not Recruiting 2026-04-21
NCT05630209 Blood Brain Barrier (BBB) Disruption Using Exablate Focused Ultrasound With Doxorubicin… Brain Tumor Active, Not Recruiting 2026-04-17
Not applicable
NCT06974916 EMBRACE Tremor BiFUS Essential Tremor Recruiting 2026-07-29
NCT03028246 A Feasibility Safety Study of Benign Centrally-Located Intracranial Tumors in Pediatric… Benign Centrally-Located Intracranial Tumors Recruiting 2026-06-29
NCT04197921 Exablate for LIFU Neuromodulation in Patients With Opioid Use Disorder (OUD) and/or Other… Opioid-use Disorder Recruiting 2026-06-26
NCT05565443 MR-guided Focused Ultrasound Plus GCase Parkinsons Disease Recruiting 2026-01-23
NCT03671889 ExAblate Blood-Brain Barrier (BBB) Disruption for the Treatment of Alzheimer's Disease Alzheimer Disease Recruiting 2026-01-09
NCT07764874 Unilateral and Staged Bilateral Pallidothalamic Tractotomy Using Exablate MRgFUS in… Parkinson Disease Not Yet Recruiting 2026-08-24
NCT06584383 A Prospective, Randomized, Controlled Trial to Test Safety and Effectiveness of… Parkinson Disease Active, Not Recruiting 2026-05-06
NCT03319485 ExAblate Pallidotomy for Medically-Refractory Dyskinesia Symptoms or Motor Fluctuations… Parkinson Disease Active, Not Recruiting 2026-03-20
NCT00147056 MRI-Guided Focused Ultrasound Feasibility Study for Brain Tumors Brain Tumor Active, Not Recruiting 2025-05-01
NCT01473485 ExAblate (Magnetic Resonance-guided Focused Ultrasound Surgery) Treatment of Brain Tumors Glioma Active, Not Recruiting 2025-05-01
NCT02252380 ExAblate Transcranial MRgFUS for the Management of Treatment-Refractory Movement Disorders Movement Disorders Active, Not Recruiting 2025-05-01
NCT02343991 Blood-Brain Barrier Disruption Using Transcranial MRI-Guided Focused Ultrasound Brain Tumor Active, Not Recruiting 2025-05-01
NCT02347254 ExAblate Transcranial MRgFUS for Unilateral Pallidotomy for the Treatment of Parkinson's… Parkinson's Disease Active, Not Recruiting 2025-05-01
NCT03998657 Continued Access of Focal MR-Guided Focused Ultrasound for Localized Intermediate Risk… Prostate Cancer Active, Not Recruiting 2025-05-01
NCT04112381 Bilateral Treatment of Medication Refractory Essential Tremor Essential Tremor Active, Not Recruiting 2025-05-01
NCT04728295 Evaluation of the Safety and Effectiveness of Bilateral Exablate Ablation of the… Parkinson Disease Active, Not Recruiting 2025-02-17
Not specified
NCT04991831 A Post-Approval Registry for Exablate 4000 Type 1.0 and Type 1.1 for Unilateral… Tremor Associated With Tremor Dominant Parkinson's Disease Recruiting 2026-03-20
NCT05539196 A Post-Approval Registry for Exablate 4000 Type 1.0 and Type 1.1 for Unilateral… Movement Disorders Recruiting 2026-03-20
NCT05386615 Post-Exablate Pregnancy Outcomes Registry Study: Exablate Treatment of Symptomatic… Uterine Fibroid Recruiting 2025-04-30
NCT03100474 Global Registry: ExAblate Neuro MR Guided Focused Ultrasound (MRgFUS) of Neurological… Essential Tremor Active, Not Recruiting 2025-05-02

Disease areas by active trials

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