Sponsor pipeline

ECOG-ACRIN Cancer Research Group clinical trial pipeline

Get alerts when ECOG-ACRIN Cancer Research Group's trials change
Data updated daily from ClinicalTrials.gov, last refresh 2026-10-16

What changed in the last 30 days

9 trials changed in the last 30 days: 0 stopped, 3 with notable changes, 6 with minor changes only.

Show 6 trials with minor changes only
  1. Minor

    Pump Chemotherapy in Addition to Standard of Care Chemotherapy Versus Standard of Care Chemotherapy Alone · Unresectable Colorectal Liver Metastases: The PUMP Trial

    Study completion moved earlier from Jun 30, 2034 to Jun 30, 2029

    Also in this update: Interventions modified

    ECOG-ACRIN Cancer Research GroupPhase 3 NCT05863195 Registry history of NCT05863195 on ClinicalTrials.gov (opens the registry)

    Updated

  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.

New trial filings, last 30 days

First postedTrialPhaseStatus
2026-10-01 NCT07852195 Testing the Use of High Dose Testosterone Followed by Darolutamide Compared to the Usual… Phase 2/3 Not Yet Recruiting

Active trials by phase

Early Phase 1
1
Phase 1/2
1
Phase 2
17
Phase 2/3
4
Phase 3
16
Not charted: 14 active trials with no phase listed on ClinicalTrials.gov (typically behavioural, device, procedure and observational studies).

Active trials top 25 of 53

NCT IDTitleConditionStatusUpdated
Phase 3
NCT05863195 Testing Pump Chemotherapy in Addition to Standard of Care Chemotherapy Versus Standard of… Metastatic Colorectal Carcinoma Recruiting 2026-09-24
NCT06475989 Study of Targeted Therapy vs. Chemotherapy in Patients With Thyroid Cancer Refractory Differentiated Thyroid Gland Carcinoma Recruiting 2026-09-24
NCT07068074 Comparing the Effectiveness of Less Invasive Procedures With the Current Standard of Care… Cutaneous Melanoma Recruiting 2026-09-24
NCT03937635 Lenalidomide, and Dexamethasone With or Without Daratumumab in Treating Patients With… Smoldering Plasma Cell Myeloma Recruiting 2026-08-19
NCT04423211 Treating Prostate Cancer That Has Come Back After Surgery With Apalutamide and Targeted… Biochemically Recurrent Prostate Carcinoma Recruiting 2026-08-19
NCT04566328 Testing the Use of Combination Therapy in Adult Patients With Newly Diagnosed Multiple… Plasma Cell Myeloma Recruiting 2026-08-19
NCT01863550 Bortezomib or Carfilzomib With Lenalidomide and Dexamethasone in Treating Patients With… Plasma Cell Myeloma Active, Not Recruiting 2026-10-05
NCT02445391 Platinum in Treating Patients With Residual Triple-Negative Breast Cancer Following… Estrogen Receptor Negative Active, Not Recruiting 2026-10-02
NCT05538663 Intravesical BCG vs GEMDOCE in NMIBC Non-muscle-invasive Bladder Cancer Active, Not Recruiting 2026-09-15
NCT05863351 Focused Radiation Versus Systemic Therapy for Kidney Cancer Patients With Limited… Metastatic Renal Cell Carcinoma Active, Not Recruiting 2026-09-15
NCT03267433 Rituximab With or Without Stem Cell Transplant in Treating Patients With Minimal Residual… Mantle Cell Lymphoma Active, Not Recruiting 2026-09-14
NCT04248452 Testing the Addition of Radiotherapy to the Usual Treatment (Chemotherapy) for Patients… Clinical Stage IV Esophageal Adenocarcinoma AJCC v8 Active, Not Recruiting 2026-09-14
NCT05721755 Combining Radiation Therapy With Immunotherapy for the Treatment of Metastatic Squamous… Clinical Stage IV HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 Active, Not Recruiting 2026-09-14
NCT03233191 Digital Tomosynthesis Mammography and Digital Mammography in Screening Patients for… Breast Screening Active, Not Recruiting 2026-09-04
NCT04484818 Testing the Addition of Darolutamide to Hormonal Therapy (Androgen Deprivation Therapy… Prostate Carcinoma Active, Not Recruiting 2026-07-28
NCT02201992 Crizotinib in Treating Patients With Stage IB-IIIA Non-small Cell Lung Cancer That Has… ALK Gene Rearrangement Active, Not Recruiting 2025-12-19
Phase 2/3
NCT07001748 Testing the Addition of Paclitaxel Administered Into the Abdominal Cavity Combined With… Gastric Adenocarcinoma Recruiting 2026-10-05
NCT07852195 Testing the Use of High Dose Testosterone Followed by Darolutamide Compared to the Usual… Metastatic Castration-Resistant Prostate Adenocarcinoma Not Yet Recruiting 2026-10-01
NCT04559139 Comparison of Chemotherapy Before and After Surgery Versus After Surgery Alone for the… Stage II Gallbladder Cancer AJCC v8 Active, Not Recruiting 2026-09-14
NCT07765433 Testing the Addition of Ivonescimab Combined With Standard Chemotherapy Compared to the… Locally Advanced Biliary Tract Adenocarcinoma Not Yet Recruiting 2026-08-14
Phase 2
NCT07040280 Sulforaphane for the Prevention of Melanoma in Patients With Multiple Atypical Nevi and a… Clinical Stage 0 Cutaneous Melanoma AJCC v8 Recruiting 2026-09-15
NCT02734537 Radiation Therapy With or Without Cisplatin in Treating Patients With Stage III-IVA… Head and Neck Squamous Cell Carcinoma Recruiting 2026-09-14
NCT06319027 Identifying Findings on Brain Scans That Could Help Make Better Predictions About Brain… Glioblastoma, IDH-Wildtype Recruiting 2026-08-18
NCT03419234 Abiraterone Acetate and Antiandrogen Therapy With or Without Cabazitaxel and Prednisone… Castration Levels of Testosterone Active, Not Recruiting 2026-10-06
NCT04001829 Docetaxel or Paclitaxel in Reducing Chemotherapy-Induced Peripheral Neuropathy in African… Anatomic Stage I Breast Cancer AJCC v8 Active, Not Recruiting 2026-10-06

Disease areas by active trials, top 10 of 28

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