Sponsor pipeline

Canadian Cancer Trials Group clinical trial pipeline

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Data updated daily from ClinicalTrials.gov, last refresh 2026-10-16

What changed in the last 30 days

2 trials changed in the last 30 days: 0 stopped, 1 with a notable change, 1 with a minor change only.

Show 1 trial with minor changes only
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.

Active trials by phase

Early Phase 1
1
Phase 1
2
Phase 1/2
2
Phase 2
24
Phase 2/3
1
Phase 3
13
Not charted: 9 active trials with no phase listed on ClinicalTrials.gov (typically behavioural, device, procedure and observational studies).

Active trials top 25 of 52

NCT IDTitleConditionStatusUpdated
Phase 3
NCT06182774 Fixed Duration vs Continuous Anti-CD38 Antibody Therapy Among Transplant Ineligible Older… Multiple Myeloma Recruiting 2026-10-14
NCT06641791 Palliative Steroeotactic Body Radiotherapy vs Palliative Standard Radiotherapy in… Advanced Head and Neck Cancer Recruiting 2026-10-14
NCT06391242 Stereotactic Body Radiotherapy vs Conventional Palliative Radiotherapy for Painful… Cancer Metastatic Recruiting 2026-08-11
NCT05451004 SPECT-CT Guided ELEctive Contralateral Neck Treatment for Patients With Lateralized… Oropharyngeal Cancer Recruiting 2026-07-14
NCT06205485 Neoadjuvant Chemotherapy, Excision And Observation vs Chemoradiotherapy For Rectal Cancer Rectal Cancer Recruiting 2026-07-14
NCT06592924 Docetaxel to Androgen Receptor Pathway Inhibitors in Patients With Metastatic Castration… Prostate Cancer (Adenocarcinoma) Recruiting 2026-07-14
NCT06686771 Radiotherapy to Block Oligoprogression In Metastatic Non-Small-Cell Lung Cancer Non-small Cell Lung Cancer Recruiting 2026-07-14
NCT02821013 Duration of Anti-PD-1 Therapy in Metastatic Melanoma Unresectable/Metastatic Melanoma Recruiting 2026-06-09
NCT03550391 Stereotactic Radiosurgery Compared With Hippocampal-Avoidant Whole Brain Radiotherapy… Brain Metastases Recruiting 2026-06-09
NCT06439225 Platinum and Taxane Chemo in Met Castration Resistant Prostate Cancer Patients With… Metastatic Castration-resistant Prostate Cancer Recruiting 2026-04-16
NCT06235697 Androgen Suppression Combined With Nodal Irradiation and Dose Escalated Prostate Treatment Prostate Cancer Recruiting 2026-04-14
NCT03488693 Regional Radiotherapy in Biomarker Low-Risk Node Positive and T3N0 Breast Cancer Breast Cancer Active, Not Recruiting 2026-07-01
NCT04650581 Fulvestrant and Ipatasertib for Advanced HER-2 Negative and Estrogen Receptor Positive… Breast Cancer Active, Not Recruiting 2026-04-13
Phase 2/3
NCT04093167 Study of CTDNA Response Adaptive Immuno-Chemotherapy in Lung Cancer Lung Cancer Active, Not Recruiting 2026-07-31
Phase 2
NCT05640999 Adjuvant Therapy in POLE-Mutated and p53-Wildtype/NSMP Early Stage Endometrial Cancer… Endometrial Cancer Recruiting 2026-10-14
NCT07341191 Sonrotoclax Plus Zanubrutinib in Patients With Relapsed/Refractory Mantle Cell Lymphoma… Mantle Cell Lymphoma Recruiting 2026-10-14
NCT03847649 A Phase II Study of Durvalumab Treatment - Substudy A: In Patients Who Discontinued Prior… Cancer Recruiting 2026-09-15
NCT05998642 Ibrutinib Combination Therapy in Transplant Ineligible Individuals With Newly Diagnosed… Non-hodgkin Lymphoma Recruiting 2026-09-15
NCT06623461 LND101 for Fecal Microbiota Transplantation in Combination With Immune Checkpoint… Melanoma Recruiting 2026-09-15
NCT06043427 Paclitaxel and Ramucirumab +/- Zanidatamab in HER2 Postive Advanced Gastroesophageal… Gastroesophageal Adenocarcinoma Recruiting 2026-08-11
NCT06880523 STRIDE (Durvalumab + Tremelimumab) With Lenvatinib vs STRIDE Alone in Unresectable… Hepatocellular Carcinoma Recruiting 2026-08-11
NCT04918186 Immunotherapy Platform Study in Platinum Resistant High Grade Serous Ovarian Cancer Ovarian Cancer Recruiting 2026-07-21
NCT05601440 Liquid-biopsy Informed Platform Trial to Evaluate CDK4/6-inhibitor Resistant ER+/HER2… Breast Cancer Recruiting 2026-05-07
NCT03297606 Canadian Profiling and Targeted Agent Utilization Trial (CAPTUR) Lymphoma, Non-Hodgkin Recruiting 2026-03-27
NCT05180097 Pembrolizumab and Brentuximab Vedotin vs GDP and Stem Cell Transplant for… Hodgkin Lymphoma Recruiting 2026-02-02

Disease areas by active trials, top 10 of 21

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