Sponsor Pipeline

Canadian Cancer Trials Group Clinical Trial Pipeline

Data updated daily from ClinicalTrials.gov — last refresh 2026-08-16
53
Active Trials
27
Recruiting
15
Phase 3
10
Disease Areas
10
Changes, 30 Days
What Changed in the Last 30 Days
DetectedTrialChange
2026-08-12 NCT05640999
Adjuvant Therapy in POLE-Mutated and p53-Wildtype/NSMP Early Stage Endometrial Cancer…
Trial sites expanded: 114 -> 118 locations
2026-08-12 NCT01396408
A Phase II Study of Sunitinib or Temsirolimus in Patients With Advanced Rare Tumours
date change Completion pushed: 2026-06-30 -> 2026-12-31
2026-08-12 NCT07390435
Feasibility and Acceptability of Collecting Sociodemographic Data in CCTG Trials
Trial sites expanded: 8 -> 11 locations
2026-08-12 NCT06043427
Paclitaxel and Ramucirumab +/- Zanidatamab in HER2 Postive Advanced Gastroesophageal…
date change Primary completion pushed: 2026-06-30 -> 2026-12-31
2026-08-12 NCT06043427
Paclitaxel and Ramucirumab +/- Zanidatamab in HER2 Postive Advanced Gastroesophageal…
date change Completion pushed: 2026-12-31 -> 2027-07-31
2026-08-12 NCT02436707
Novel Combination Therapy in the Treatment of Relapsed and Refractory Aggressive B-Cell…
date change Primary completion pushed: 2026-06-30 -> 2026-12-31
2026-08-01 NCT04093167
Study of CTDNA Response Adaptive Immuno-Chemotherapy in Lung Cancer
Enrollment closed, study ongoing
2026-08-01 NCT04093167
Study of CTDNA Response Adaptive Immuno-Chemotherapy in Lung Cancer
Enrollment reduced: 230 -> 53 participants
2026-07-21 NCT05470010
Smartphone App-Based Mindfulness Intervention for French and English Speaker Cancer…
overall status: Recruiting → Active, Not Recruiting
2026-07-21 NCT05470010
Smartphone App-Based Mindfulness Intervention for French and English Speaker Cancer…
Enrollment reduced: 345 -> 300 participants
Active Trials by Phase
Phase 3
14
Phase 2/3
1
Phase 2
24
Phase 1/2
2
Phase 1
2
Early Phase 1
1
Not specified
9
Active Trials — top 25 of 53
NCT IDTitleConditionStatus
Phase 3
NCT06235697 Androgen Suppression Combined With Nodal Irradiation and Dose Escalated Prostate Treatment Prostate Cancer Recruiting
NCT06439225 Platinum and Taxane Chemo in Met Castration Resistant Prostate Cancer Patients With… Metastatic Castration-resistant Prostate Cancer Recruiting
NCT02821013 Duration of Anti-PD-1 Therapy in Metastatic Melanoma Unresectable/Metastatic Melanoma Recruiting
NCT03550391 Stereotactic Radiosurgery Compared With Hippocampal-Avoidant Whole Brain Radiotherapy… Brain Metastases Recruiting
NCT05451004 SPECT-CT Guided ELEctive Contralateral Neck Treatment for Patients With Lateralized… Oropharyngeal Cancer Recruiting
NCT06182774 Fixed Duration vs Continuous Anti-CD38 Antibody Therapy Among Transplant Ineligible Older… Multiple Myeloma Recruiting
NCT06205485 Neoadjuvant Chemotherapy, Excision And Observation vs Chemoradiotherapy For Rectal Cancer Rectal Cancer Recruiting
NCT06592924 Docetaxel to Androgen Receptor Pathway Inhibitors in Patients With Metastatic Castration… Prostate Cancer (Adenocarcinoma) Recruiting
NCT06641791 Palliative Steroeotactic Body Radiotherapy vs Palliative Standard Radiotherapy in… Advanced Head and Neck Cancer Recruiting
NCT06686771 Radiotherapy to Block Oligoprogression In Metastatic Non-Small-Cell Lung Cancer Non-small Cell Lung Cancer Recruiting
NCT06391242 Stereotactic Body Radiotherapy vs Conventional Palliative Radiotherapy for Painful… Cancer Metastatic Recruiting
NCT02273375 Double Blind Placebo Controlled Controlled Study of Adjuvant MEDI4736 In Completely… Non-Small Cell Lung Cancer Active, Not Recruiting
NCT04650581 Fulvestrant and Ipatasertib for Advanced HER-2 Negative and Estrogen Receptor Positive… Breast Cancer Active, Not Recruiting
NCT03488693 Regional Radiotherapy in Biomarker Low-Risk Node Positive and T3N0 Breast Cancer Breast Cancer Active, Not Recruiting
Phase 2/3
NCT04093167 Study of CTDNA Response Adaptive Immuno-Chemotherapy in Lung Cancer Lung Cancer Active, Not Recruiting
Phase 2
NCT05180097 Pembrolizumab and Brentuximab Vedotin vs GDP and Stem Cell Transplant for… Hodgkin Lymphoma Recruiting
NCT03297606 Canadian Profiling and Targeted Agent Utilization Trial (CAPTUR) Lymphoma, Non-Hodgkin Recruiting
NCT05998642 Ibrutinib Combination Therapy in Transplant Ineligible Individuals With Newly Diagnosed… Non-hodgkin Lymphoma Recruiting
NCT05601440 Liquid-biopsy Informed Platform Trial to Evaluate CDK4/6-inhibitor Resistant ER+/HER2… Breast Cancer Recruiting
NCT06623461 LND101 for Fecal Microbiota Transplantation in Combination With Immune Checkpoint… Melanoma Recruiting
NCT03847649 A Phase II Study of Durvalumab Treatment - Substudy A: In Patients Who Discontinued Prior… Cancer Recruiting
NCT04918186 Immunotherapy Platform Study in Platinum Resistant High Grade Serous Ovarian Cancer Ovarian Cancer Recruiting
NCT05640999 Adjuvant Therapy in POLE-Mutated and p53-Wildtype/NSMP Early Stage Endometrial Cancer… Endometrial Cancer Recruiting
NCT06043427 Paclitaxel and Ramucirumab +/- Zanidatamab in HER2 Postive Advanced Gastroesophageal… Gastroesophageal Adenocarcinoma Recruiting
NCT06880523 STRIDE (Durvalumab + Tremelimumab) With Lenvatinib vs STRIDE Alone in Unresectable… Hepatocellular Carcinoma Recruiting
See all 53 active Canadian Cancer Trials Group trials with filters →
Disease Areas
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