Sponsor pipeline

BeOne Medicines clinical trial pipeline

Get alerts when BeOne Medicines's trials change

50 active trials 36 recruiting 15 Phase 3 19 disease areas 29 changes in 30 days

Data updated daily from ClinicalTrials.gov, last refresh 2026-10-02

What changed in the last 30 days

2026-09-15
Primary completion pushed: 2028-02-08 → 2028-08-31
Completion pushed: 2028-02-08 → 2028-08-31
NCT04771130 A Study of BGB-11417 in Participants With Myeloid Malignancies · Phase 1/2
2026-09-23
Primary endpoint(s) modified
Sponsor changed: BeiGene → BeOne Medicines
Results posted: 2026-09-22
Interventions modified
Trial sites reduced: 104 → 65 locations
Trial arms changed: 1 → 4
NCT05471843 Study of Sonrotoclax (BGB-11417) Monotherapy in Participants With Relapsed or Refractory… · Phase 1/2
2026-09-09
Primary endpoint(s) modified
Phase changed: Phase 1 → Phase 1/2
Enrollment increased: 392 → 630 participants
Primary completion moved earlier: 2028-05-30 → 2027-03-31
Completion pushed: 2028-05-30 → 2028-10-31
Trial arms changed: 6 → 7
NCT06427941 A Phase 1/2 Study of BGB-B2033, Alone or in Combination With Tislelizumab With or Without… · Phase 1/2
2026-09-19
Recruitment opened
NCT07733180 A Study Investigating Alternate Schedules of Tislelizumab Plus Chemotherapy in Japanese… · Phase 2
2026-09-12
Recruitment opened
NCT07746141 A First-in-Human Study Investigating BG-85738 Alone or in Combination With Other… · Phase 1
2026-09-10
Sponsor refiled this as recruiting (was completed)
NCT07005713 A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of… · Phase 1
2026-09-29
Trial sites expanded: 162 → 189 locations
NCT07492641 BGB-43395 Plus Letrozole Versus CDK4/6i Plus Letrozole for Patients With Advanced or… · Phase 3
2026-09-29
Trial sites reduced: 155 → 150 locations
NCT06742996 A Study to Investigate the Efficacy and Safety of Sonrotoclax Plus Zanubrutinib Compared… · Phase 3
2026-09-29
Trial sites expanded: 214 → 217 locations
NCT06973187 A Study to Evaluate the Safety and Efficacy of Tacabrutideg (BGB-16673) Compared to… · Phase 3
2026-09-29
Trial sites expanded: 17 → 20 locations
NCT06697184 A Study to Investigate the Safety of Novel Dose Ramp-up Schedule(s) When Initiating… · Phase 1/2
2026-09-16
Trial sites expanded: 108 → 162 locations
NCT07492641 BGB-43395 Plus Letrozole Versus CDK4/6i Plus Letrozole for Patients With Advanced or… · Phase 3
2026-09-12
Trial sites expanded: 209 → 214 locations
NCT06973187 A Study to Evaluate the Safety and Efficacy of Tacabrutideg (BGB-16673) Compared to… · Phase 3
2026-09-12
Trial sites expanded: 105 → 114 locations
NCT07277231 A Study to Investigate Sonrotoclax (BGB-11417) Plus Zanubrutinib (BGB-3111) Compared With… · Phase 3
2026-09-15
Trial sites reduced: 82 → 78 locations
NCT04973605 A Phase 1b/2 Study of Sonrotoclax (BGB-11417) as Monotherapy and in Various Combinations… · Phase 1/2
2026-10-01
Primary completion confirmed: April 2026 (last estimated March 2027)
NCT04002297 A Study to Investigate the Efficacy of Zanubrutinib Plus Rituximab Compared With… · Phase 3
2026-09-15
Trial sites expanded: 13 → 16 locations
NCT07619287 An Investigational Study of BG-75202 Alone and in Combination With Other Agents in… · Phase 1
2026-09-15
Trial sites expanded: 98 → 101 locations
NCT06589596 An Investigational Study of BGB-58067 As a Single Agent and in Combination With… · Phase 1
2026-09-12
Trial sites expanded: 30 → 34 locations
NCT06598800 Study of BG-T187 Alone and in Combination With Other Therapeutic Agents in Participants… · Phase 1

New trial filings, last 30 days

First postedTrialPhaseStatus
2026-09-23 NCT07836530 Study Comparing BGB-B2033 With Sorafenib or Lenvatinib in Relapsed Hepatocellular… Phase 3 Not Yet Recruiting
2026-09-15 NCT07820891 A Trial in Healthy Participants to Assess Drug Interaction Potential of BGB-43395 Phase 1 Not Yet Recruiting
2026-09-10 NCT07811271 Efficacy and Safety of BG-C9074 With Bevacizumab Compared With Bevacizumab in Adults With… Phase 3 Not Yet Recruiting

Active trials by phase

Phase 1
22
Phase 1/2
8
Phase 2
4
Phase 2/3
1
Phase 3
14
Not charted: 1 active trial with no phase listed on ClinicalTrials.gov (typically behavioural, device, procedure and observational studies).

Active trials top 25 of 50

NCT IDTitleConditionStatusUpdated
Phase 3
NCT06742996 A Study to Investigate the Efficacy and Safety of Sonrotoclax Plus Zanubrutinib Compared… Mantle Cell Lymphoma Recruiting 2026-09-28
NCT06846671 A Study of Tacabrutideg (BGB-16673) Compared to Investigator's Choice in Participants… CLL Recruiting 2026-09-28
NCT06943872 A Study to Investigate Progression-Free Survival With Sonrotoclax Plus Obinutuzumab Or… Chronic Lymphocytic Leukemia Recruiting 2026-09-28
NCT06973187 A Study to Evaluate the Safety and Efficacy of Tacabrutideg (BGB-16673) Compared to… Chronic Lymphocytic Leukemia Recruiting 2026-09-28
NCT07277231 A Study to Investigate Sonrotoclax (BGB-11417) Plus Zanubrutinib (BGB-3111) Compared With… Chronic Lymphocytic Leukemia Recruiting 2026-09-28
NCT07492641 BGB-43395 Plus Letrozole Versus CDK4/6i Plus Letrozole for Patients With Advanced or… HR+/HER2- Breast Cancer Recruiting 2026-09-28
NCT07043400 A Study to Investigate Tislelizumab Administered as Subcutaneous Injection Versus… Metastatic Gastric Adenocarcinoma Recruiting 2026-09-14
NCT04002297 A Study to Investigate the Efficacy of Zanubrutinib Plus Rituximab Compared With… Mantle Cell Lymphoma; Non-Hodgkin Lymphoma Active, Not Recruiting 2026-09-30
NCT05100862 A Study of Zanubrutinib Plus Anti-CD20 Versus Lenalidomide Plus Rituximab in Participants… Relapsed/Refractory Follicular Lymphoma Active, Not Recruiting 2026-09-28
NCT06073821 Study of Sonrotoclax (BGB-11417) Plus Zanubrutinib (BGB-3111) Compared With Venetoclax… CLL Active, Not Recruiting 2026-09-28
NCT07836530 Study Comparing BGB-B2033 With Sorafenib or Lenvatinib in Relapsed Hepatocellular… Hepatocellular Carcinoma Not Yet Recruiting 2026-09-23
NCT07811271 Efficacy and Safety of BG-C9074 With Bevacizumab Compared With Bevacizumab in Adults With… Epithelial Ovarian Cancer Not Yet Recruiting 2026-09-10
NCT04170283 A Study to Evaluate Long-term Safety of Zanubrutinib Regimens in Participants With B-Cell… B-cell Malignancies Active, Not Recruiting 2026-08-28
NCT06970743 A Study of BGB-16673 Compared to Investigator's Choice in Participants With… Chronic Lymphocytic Leukemia Active, Not Recruiting 2026-08-24
Phase 2/3
NCT05707377 A Study to Examine the Efficacy and Safety of Zanubrutinib Given to Adults With Primary… Primary Membranous Nephropathy Active, Not Recruiting 2026-09-11
Phase 2
NCT07733180 A Study Investigating Alternate Schedules of Tislelizumab Plus Chemotherapy in Japanese… Advanced Esophageal Squamous Cell Carcinoma Recruiting 2026-09-28
NCT07554521 A Study to Evaluate Efficacy and Safety of Tislelizumab Plus Chemotherapy for Locally… Advanced Unresectable Gastric Adenocarcinoma Recruiting 2026-08-24
NCT06637501 A Study to Investigate Sonrotoclax Combined With Zanubrutinib Versus Zanubrutinib Alone… Chronic Lymphocytic Leukemia Active, Not Recruiting 2026-07-09
NCT05952037 A Study to Investigate Efficacy and Safety of BCL2 Inhibitor Sonrotoclax as Monotherapy… Waldenstrom Macroglobulinemia Active, Not Recruiting 2026-01-02
Phase 1/2
NCT04973605 A Phase 1b/2 Study of Sonrotoclax (BGB-11417) as Monotherapy and in Various Combinations… Relapsed/Refractory Multiple Myeloma Recruiting 2026-09-28
NCT05006716 A Dose-Escalation and Expansion Study of Tacabrutideg (BGB-16673) in Participants With… B-cell Malignancy Recruiting 2026-09-28
NCT06697184 A Study to Investigate the Safety of Novel Dose Ramp-up Schedule(s) When Initiating… Chronic Lymphocytic Leukemia Recruiting 2026-09-28
NCT06427941 A Phase 1/2 Study of BGB-B2033, Alone or in Combination With Tislelizumab With or Without… Metastatic Hepatocellular Carcinoma Recruiting 2026-09-16
NCT04771130 A Study of BGB-11417 in Participants With Myeloid Malignancies Acute Myeloid Leukemia Recruiting 2026-09-14
NCT06634589 A Study to Investigate Safety and Effectiveness of Tacabrutideg (BGB-16673) in… B-cell Malignancy Recruiting 2026-09-11
See all 50 active BeOne Medicines trials with filters →

Disease areas by active trials, top 10 of 19

Leukemia (10) · Chronic Lymphocytic Leukemia (CLL) (9) · Mantle Cell Lymphoma (5) · Breast Cancer (4) · Non-Hodgkin Lymphoma (4) · Gastric Cancer (3) · Acute Myeloid Leukemia (AML) (2) · Esophageal Cancer (2) · Follicular Lymphoma (2) · Liver Cancer (2)

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