Drug Pipeline

Varenicline Clinical Trials

Data updated daily from ClinicalTrials.gov — last refresh 2026-06-12
20
Active Studies
12
Recruiting
4
Phase 3
10
Top Sponsors
2
Changes, 30 Days
What Changed in the Last 30 Days
DetectedTrialChange
2026-06-09 NCT07596485
RP-008 in Combination With Daily Oral Varenicline for the Treatment of Trigeminal…
date change Primary completion pushed: 2028-12 -> 2029-02
2026-06-09 NCT07596485
RP-008 in Combination With Daily Oral Varenicline for the Treatment of Trigeminal…
date change Completion pushed: 2028-12 -> 2029-02
New Trial Filings, Last 30 Days
First PostedTrialPhaseStatus
2026-05-26 NCT07606625 Ocular Surface Health and Tear Film Stability With a Nasal Spray Dry Eye Treatment Phase 4 Recruiting
2026-05-19 NCT07596485 RP-008 in Combination With Daily Oral Varenicline for the Treatment of Trigeminal… Phase 1/2 Recruiting
Active Studies by Phase
Phase 4
8
Phase 3
3
Phase 2/3
1
Phase 2
4
Phase 1/2
1
Early Phase 1
2
Not specified
1
Active Trials
NCT IDTitleConditionStatus
Phase 4
NCT06832085 Combination Nicotine Replacement Therapy, Cytisine, or Varenicline for Smoking Cessation Tobacco Recruiting
NCT06474299 The Avenues Study: Dual Use Cessation Smoking Cessation Recruiting
NCT04604509 Nicotine Replacement Therapy, Counseling, Varenicline, and Bupropion for Smoking… Cigarette Smoking-Related Carcinoma Recruiting
NCT07606625 Ocular Surface Health and Tear Film Stability With a Nasal Spray Dry Eye Treatment Dry Eye Recruiting
NCT05694637 Botswana Smoking and Abstinence Reinforcement Trial Smoking Cessation Enrolling by Invitation
NCT07145866 Varenicline and Accelerated Transcranial Magnetic Stimulation (TMS) for Quitting Nicotine… Nicotine Dependence Not Yet Recruiting
NCT02162849 Reward Sensitivity and Pharmacotherapy for Smoking Cessation Tobacco Use Cessation Active, Not Recruiting
NCT06966362 Varenicline for Smoking Reduction in Veterans Not Ready To Quit Veterans Not Yet Recruiting
Phase 3
NCT05703672 Switching to E-cigarettes in Smokers Not Interested in Quitting Smoking Reduction Recruiting
NCT06883162 Cannabis-Tobacco Co-Use Treatment Study Tobacco Use Disorder Recruiting
NCT04176172 Optimizing Tobacco Use Treatment for PLWHA HIV/AIDS Active, Not Recruiting
Phase 2/3
NCT05413122 Evaluating Smoking Cessation Interventions for PWH in South Africa Smoking Cessation Recruiting
Phase 2
NCT06679374 Reducing Falls With Varenicline in Hypocholinergic Parkinson Disease Parkinson Disease Recruiting
NCT06609369 Neural Mechanisms Connecting Deficient Sleep and Smoking Relapse Tobacco Use Recruiting
NCT06006143 Off-Label Medications for Alcohol Use Disorder Among Patients With HIV: Pilot Study 2 Alcohol Use Disorder Active, Not Recruiting
NCT07099638 Trial of Varenicline With Nicotine Lozenges and a Smartphone Medication Adherence… Smoking Cessation Not Yet Recruiting
Phase 1/2
NCT07596485 RP-008 in Combination With Daily Oral Varenicline for the Treatment of Trigeminal… Trigeminal Neuralgia Recruiting
Early Phase 1
NCT06582888 Advancing VR-based Attentional Bias as a Biomarker for Tobacco Use Disorder Nicotine Addiction Recruiting
NCT01098955 Smoking Cessation Treatment for Head & Neck Cancer Patients Head and Neck Cancer Active, Not Recruiting
Not specified
NCT05642715 Trial of a Harm Reduction Strategy for People With HIV Who Smoke Cigarettes Hiv Recruiting
Sponsors Running Varenicline Trials
Disease Areas
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