Botswana Smoking and Abstinence Reinforcement Trial

Many people living with HIV in southern Africa, specifically Botswana use tobacco products. Using tobacco makes some of the effects of HIV worse and even causes excess deaths. The investigators plan to use an intervention called Screening, Brief Intervention and Referral to Treatment (SBIRT) to help people to quit smoking and also a drug called varenicline. Apart from helping people to stop smoking, the investigators will also test to see how task shifting can be used to help people stop smoking in a sustainable way. Finally, the investigators will estimate the cost of the intervention.

NCT Number	NCT05694637
Lead Sponsor	University of Maryland, Baltimore Collaborators: University of Maryland, Baltimore County, University of Maryland, College Park, University of Chicago
Conditions	Smoking Cessation, Hiv
Enrollment	750 participants
Start Date	2023-07-25
Primary Completion	2027-02-01 (estimated)
Study Completion	2027-08-31 (estimated)
Updated on ClinicalTrials.gov	2026-01-09