Drug Pipeline

Thiotepa Clinical Trials

Data updated daily from ClinicalTrials.gov — last refresh 2026-06-12
36
Active Studies
19
Recruiting
5
Phase 3
10
Top Sponsors
5
Changes, 30 Days
What Changed in the Last 30 Days
DetectedTrialChange
2026-06-03 NCT03786783
Dinutuximab, Sargramostim, and Combination Chemotherapy in Treating Patients With Newly…
Trial completed
2026-06-03 NCT03786783
Dinutuximab, Sargramostim, and Combination Chemotherapy in Treating Patients With Newly…
date change Completion moved earlier: 2026-09-19 -> 2026-03-31
2026-05-15 NCT07566377
Cord Blood Transplantation in Children and Young Adults With Blood Cancer
Trial arms changed: 6 -> 2
2026-05-15 NCT07566377
Cord Blood Transplantation in Children and Young Adults With Blood Cancer
Trial sites reduced: 7 -> 1 locations
2026-05-14 NCT05208944
THIO Sequenced With Cemiplimab in Advanced NSCLC
overall status: "Recruiting" → "Active Not Recruiting"
New Trial Filings, Last 30 Days
First PostedTrialPhaseStatus
2026-06-01 NCT07616154 Haploidentical Donor Hematopoietic Cell Transplant for Sickle Cell Disease Phase 2 Not Yet Recruiting
Active Studies by Phase
Phase 3
3
Phase 2/3
2
Phase 2
20
Phase 1/2
3
Phase 1
5
Early Phase 1
2
Not specified
1
Active Trials — top 25 of 36
NCT IDTitleConditionStatus
Phase 3
NCT06908304 A Phase III Study With THIO + Cemiplimab vs Chemotherapy as 3rd Line Treatment in… Carcinoma, Non-Small -Cell Lung Recruiting
NCT03126916 Testing the Addition of 131I-MIBG or Lorlatinib to Intensive Therapy in People With… Ganglioneuroblastoma Recruiting
NCT06172296 Dinutuximab With Chemotherapy, Surgery and Stem Cell Transplantation for the Treatment of… Ganglioneuroblastoma, Nodular Recruiting
Phase 2/3
NCT04708054 Venetoclax to Improve Outcomes of Fractionated Busulfan Regimen in Patients With… Acute Myeloid Leukemia Recruiting
NCT04217278 A Trial of Treatments to Assess the Effects on Outcome of Adults With AML and MDS… Acute Myeloid Leukaemia Active, Not Recruiting
Phase 2
NCT06013423 Cord Blood Transplant, Cyclophosphamide, Fludarabine, and Total-Body Irradiation in… Acute Leukemia of Ambiguous Lineage Recruiting
NCT06252870 Study Testing Two Conditioning Regimen With a Single Prophylaxis of GVHD by… Graft Versus Host Disease Recruiting
NCT03970096 Graft Versus Host Disease-Reduction Strategies for Donor Blood Stem Cell Transplant… Acute Leukemia Recruiting
NCT03980769 Donor Stem Cell Transplant With Treosulfan, Fludarabine, and Thiotepa in Treating… Non-Neoplastic Hematopoietic and Lymphoid Cell Disorder Recruiting
NCT06687772 CNS-Relapse Prevention in High-Risk Diffuse Large B-cell Lymphoma With Thiotepa-based… Diffuse Large B Cell Lymphoma Recruiting
NCT06807606 Optimized Cord Blood Transplantation for the Treatment of Patients With High-risk… Hematologic Malignancies Recruiting
NCT04684368 A Study of a New Way to Treat Children and Young Adults With a Brain Tumor Called NGGCT Central Nervous System Nongerminomatous Germ Cell Tumor Recruiting
NCT03779854 Naive T Cell Depletion for Preventing Chronic Graft-versus-Host Disease in Children and… Acute Biphenotypic Leukemia Recruiting
NCT07566377 Cord Blood Transplantation in Children and Young Adults With Blood Cancer Acute Myelogenous Leukemia Recruiting
NCT01746849 Palifermin With Leuprolide Acetate for the Promotion of Immune Recovery Following Total… Leukemia Active, Not Recruiting
NCT02870907 Adjuvant Treatment in Extensive Unilateral Retinoblastoma Primary Enucleated (RB SFCE… Retinoblastoma Active, Not Recruiting
NCT01511562 Combination Chemotherapy With or Without Autologous Stem Cell Transplant in Treating… Lymphoma Active, Not Recruiting
NCT02861417 Busulfan, Fludarabine Phosphate, and Post-Transplant Cyclophosphamide in Treating… Hematopoietic and Lymphoid Cell Neoplasm Active, Not Recruiting
NCT07441967 The Safety and Efficacy of the Regimen of Thiotepa + Fludarabine +Granulocyte… Hematologic Malignancies Not Yet Recruiting
NCT05565105 CD34+ Transplants for Leukemia and Lymphoma Leukemia, Myeloid, Acute Not Yet Recruiting
NCT04859946 Itacitinib for the Prevention of Graft Versus Host Disease Hematologic and Lymphocytic Disorder Active, Not Recruiting
NCT04872595 A Modified Dose of Rabbit Anti-thymocyte Globulin (rATG) in Children and Adults Receiving… Acute Myeloid Leukemia (AML) Active, Not Recruiting
NCT05208944 THIO Sequenced With Cemiplimab in Advanced NSCLC Carcinoma, Non-Small-Cell Lung Active, Not Recruiting
NCT07616154 Haploidentical Donor Hematopoietic Cell Transplant for Sickle Cell Disease Sickle Cell Disease Not Yet Recruiting
NCT03849651 TCRαβ-depleted Progenitor Cell Graft With Additional Memory T-cell DLI, Plus Selected Use… Acute Lymphoblastic Leukemia (ALL) Active, Not Recruiting
Sponsors Running Thiotepa Trials
Disease Areas
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