| Phase 3 |
| NCT04166409 |
A Study of the Drugs Selumetinib vs. Carboplatin and Vincristine in Patients With… |
Low Grade Astrocytoma |
Recruiting |
| NCT04924608 |
Efficacy and Safety of Selumetinib in Adults With NF1 Who Have Symptomatic, Inoperable… |
Neurofibromatosis 1 |
Active, Not Recruiting |
| NCT03871257 |
A Study of the Drugs Selumetinib Versus Carboplatin/Vincristine in Patients With… |
Low Grade Glioma |
Active, Not Recruiting |
| NCT04576117 |
A Study to Compare Treatment With the Drug Selumetinib Alone Versus Selumetinib and… |
Recurrent Low Grade Astrocytoma |
Active, Not Recruiting |
| Phase 2 |
| NCT06188741 |
Selumetinib for the Prevention of Plexiform Neurofibroma Growth in NF Type 1 |
Neurofibromatosis 1 |
Recruiting |
| NCT05554328 |
Testing the Use of the Combination of Selumetinib and Olaparib or Selumetinib Alone… |
Recurrent Endometrial Carcinoma |
Recruiting |
| NCT05564377 |
Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced… |
Advanced Malignant Solid Neoplasm |
Recruiting |
| NCT02407405 |
MEK 1/2 Inhibitor Selumetinib (AZD6244 Hydrogen Sulfate) in Adults With Neurofibromatosis… |
Neurofibromatosis 1 (NF1) |
Active, Not Recruiting |
| NCT03392246 |
A Phase 2 Study of Osimertinib in Combination With Selumetinib in EGFR Inhibitor naïve… |
Non-small Cell Lung Cancer |
Active, Not Recruiting |
| NCT03155620 |
Targeted Therapy Directed by Genetic Testing in Treating Pediatric Patients With Relapsed… |
Advanced Malignant Solid Neoplasm |
Active, Not Recruiting |
| Phase 1/2 |
| NCT02813135 |
European Proof-of-Concept Therapeutic Stratification Trial of Molecular Anomalies in… |
Pediatric Cancer |
Recruiting |
| NCT01089101 |
Selumetinib in Treating Young Patients With Recurrent or Refractory Low Grade Glioma |
Low Grade Glioma |
Active, Not Recruiting |
| NCT01362803 |
AZD6244 Hydrogen Sulfate for Children With Nervous System Tumors |
Neurofibromatosis 1 |
Active, Not Recruiting |
| NCT07619521 |
Testing the Combination of Anti-Cancer Drugs, Selumetinib and DS-8201a, for Advanced… |
Advanced Pancreatic Ductal Adenocarcinoma |
Not Yet Recruiting |
| Phase 1 |
| NCT03326310 |
Selumetinib and Azacitidine in High Risk Chronic Blood Cancers |
Chronic Myeloid Leukemia |
Recruiting |
| NCT02546661 |
Open-Label, Randomised, Multi-Drug, Biomarker-Directed, Phase 1b Study in Pts w/ Muscle… |
Muscle Invasive Bladder Cancer |
Active, Not Recruiting |
| NCT06502171 |
Study of Cabozantinib With Selumetinib for Plexiform Neurofibromas |
Neurofibromatosis 1 |
Not Yet Recruiting |
| NCT01364051 |
Cediranib Maleate and Selumetinib Sulfate in Treating Patients With Solid Malignancies |
Metastatic Melanoma |
Active, Not Recruiting |
| NCT03162627 |
Selumetinib and Olaparib in Solid Tumors |
Malignant Neoplasm of Breast |
Active, Not Recruiting |
| NCT04590235 |
A Study of Selumetinib in Chinese Paediatric and Adult Subjects With Neurofibromatosis… |
Neurofibromatosis 1 |
Active, Not Recruiting |
| NCT05101148 |
Phase I Study to Assess the Effect of Food on the PK and Gastrointestinal Tolerability of… |
Neurofibromatosis Type 1 |
Active, Not Recruiting |
| NCT00463814 |
AZD6244 (ARRY-142886) Solid Oral Dosage Formulation in Participants With Advanced Solid… |
Tumor |
Active, Not Recruiting |