Drug Pipeline

Sapanisertib Clinical Trials

Data updated daily from ClinicalTrials.gov — last refresh 2026-06-12
9
Active Studies
2
Recruiting
2
Top Sponsors
2
Changes, 30 Days
What Changed in the Last 30 Days
DetectedTrialChange
2026-06-12 NCT02503722
Testing the Combination of MLN0128 (TAK-228) and AZD9291 in Advanced EGFR (Epidermal…
date change Primary completion pushed: 2026-06-05 -> 2027-02-28
2026-06-12 NCT02503722
Testing the Combination of MLN0128 (TAK-228) and AZD9291 in Advanced EGFR (Epidermal…
date change Completion pushed: 2026-06-05 -> 2027-02-28
Active Studies by Phase
Phase 2
4
Phase 1/2
2
Phase 1
3
Active Trials
NCT IDTitleConditionStatus
Phase 2
NCT03047213 Sapanisertib in Treating Patients With Locally Advanced or Metastatic Bladder Cancer With… Locally Advanced Bladder Urothelial Carcinoma Active, Not Recruiting
NCT06385496 Testing MLN0128 (TAK-228) as Potentially Targeted Treatment in Cancers With mTOR Genetic… Advanced Lymphoma Active, Not Recruiting
NCT06390865 Testing MLN0128 (TAK-228) as Potentially Targeted Treatment in Cancers With TSC1 or TSC2… Advanced Lymphoma Active, Not Recruiting
NCT02465060 Targeted Therapy Directed by Genetic Testing in Treating Patients With Advanced… Advanced Lymphoma Active, Not Recruiting
Phase 1/2
NCT07558733 Sapanisertib and Serabelisib (PIKTOR) in Various Combinations in Patients With HR+/HER2… HR+ HER2- Breast Cancer Recruiting
NCT06811116 Testing the Addition of an Anti-cancer Drug, Sapanisertib, to the Usual Chemotherapy… Advanced Hepatocellular Carcinoma Recruiting
Phase 1
NCT02142803 TORC1/2 Inhibitor MLN0128 and Bevacizumab in Treating Patients With Recurrent… Adult Glioblastoma Active, Not Recruiting
NCT04250545 Testing of the Anti Cancer Drugs CB-839 HCl (Telaglenastat) and MLN0128 (Sapanisertib) in… Leptomeningeal Neoplasm Active, Not Recruiting
NCT02503722 Testing the Combination of MLN0128 (TAK-228) and AZD9291 in Advanced EGFR (Epidermal… Metastatic Lung Non-Small Cell Carcinoma Active, Not Recruiting
Sponsors Running Sapanisertib Trials
Disease Areas
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