Drug Pipeline

Larotrectinib Clinical Trials

Data updated daily from ClinicalTrials.gov — last refresh 2026-06-12
9
Active Studies
5
Recruiting
5
Top Sponsors
Active Studies by Phase
Phase 2
6
Early Phase 1
1
Not specified
2
Active Trials
NCT IDTitleConditionStatus
Phase 2
NCT04879121 Larotrectinib for the Treatment of NTRK Amplification Positive, Locally Advanced or… Locally Advanced Malignant Solid Neoplasm Recruiting
NCT06563999 Neoadjuvant Umbrella Trial for Patients With Unresectable Stage III NSCLC Harboring Rare… Lung Cancer Stage III Recruiting
NCT06390852 Testing LOXO-101 as Potentially Targeted Treatment in Cancers With NTRK Genetic Changes… Advanced Lymphoma Active, Not Recruiting
NCT03155620 Targeted Therapy Directed by Genetic Testing in Treating Pediatric Patients With Relapsed… Advanced Malignant Solid Neoplasm Active, Not Recruiting
NCT03213704 Larotrectinib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors… Advanced Malignant Solid Neoplasm Active, Not Recruiting
NCT02465060 Targeted Therapy Directed by Genetic Testing in Treating Patients With Advanced… Advanced Lymphoma Active, Not Recruiting
Early Phase 1
NCT04655404 A Pilot Study of Larotrectinib for Newly-Diagnosed High-Grade Glioma With NTRK Fusion High Grade Glioma Recruiting
Not specified
NCT04142437 Study to Learn More About the Safety and Effectiveness of the Drug VITRAKVI During… Locally Advanced or Metastatic Solid Tumor Harboring an NTRK Gene Fusion Recruiting
NCT04945330 NTRK Gene Fusion - Positive Advanced or Recurrent Solid Tumors, a Rare Cancer Caused by… Advanced or Recurrent Solid Tumor Harboring an NTRK Gene Fusion Recruiting
Sponsors Running Larotrectinib Trials
Disease Areas
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