Drug Pipeline

FOLFOX Clinical Trials

Data updated daily from ClinicalTrials.gov — last refresh 2026-06-12
29
Active Studies
20
Recruiting
10
Phase 3
10
Top Sponsors
2
Changes, 30 Days
What Changed in the Last 30 Days
DetectedTrialChange
2026-05-29 NCT07221357
A Study to Evaluate the Safety and Efficacy of Pumitamig in Combination With Chemotherapy…
Trial sites expanded: 279 -> 286 locations
2026-05-27 NCT04929223
A Study Evaluating the Safety and Efficacy of Targeted Therapies in Subpopulations of…
Trial sites expanded: 76 -> 82 locations
New Trial Filings, Last 30 Days
First PostedTrialPhaseStatus
2026-06-02 NCT07622017 KORTUC (KRC-01) Plus Radiotherapy for Organ Preservation in Rectal Cancer Phase 2 Not Yet Recruiting
2026-05-22 NCT07603375 Upfront Chemotherapy With Radiation Therapy (CRT) Followed by Chemotherapy in Localized… Phase 2 Not Yet Recruiting
Active Studies by Phase
Phase 3
7
Phase 2/3
3
Phase 2
10
Phase 1/2
3
Phase 1
5
Early Phase 1
1
Active Trials — top 25 of 29
NCT IDTitleConditionStatus
Phase 3
NCT07315750 A Study of Disitamab Vedotin Combined With Trastuzumab and Tislelizumab Versus… Gastric Carcinoma Recruiting
NCT05855200 Study of Perioperative Dostarlimab in Participants With Untreated T4N0 or Stage III… Colonic Neoplasms Recruiting
NCT07389265 Continuation of Cetuximab Beyond First-Line Progression in Metastatic Colorectal Cancer Metastatic Colorectal Cancer (mCRC) Recruiting
NCT07528209 Neoadjuvant CAPOX With or Without Pucotenlimab Plus Selective Radiotherapy for Locally… Rectal Cancer Recruiting
NCT07284849 A Study to Evaluate the Efficacy and Safety of Standard-of-Care Chemotherapy and… CRC (Colorectal Cancer) Recruiting
NCT06783491 Efficacy of the Use of Neoadjuvant With/Without Hyperthermic Intraperitoneal Chemotherapy… Locally Advanced Colorectal Cancer Recruiting
NCT07472868 Neoadjuvant FOLFOXIRI and Chemoradiotherapy Versus Neoadjuvant CAPOX/FOLFOX and… Locally Advanced Rectal Carcinoma Not Yet Recruiting
Phase 2/3
NCT06279130 Pan-tumor Neoadjuvant Basket Study of Immune Check-point Inhibition and Novel… Resectable MMR-deficient Solid Tumors Recruiting
NCT07221357 A Study to Evaluate the Safety and Efficacy of Pumitamig in Combination With Chemotherapy… Untreated, Unresectable, or Metastatic Colorectal Cancer Recruiting
NCT07221149 A Study to Evaluate the Safety and Efficacy of Pumitamig in Combination With Chemotherapy… Untreated Advanced or Metastatic Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma Recruiting
Phase 2
NCT07294664 PD1/TGFβ In Combination With SHR2554 or Apatinib And Chemotherapy For First - Line… Advanced Gastric Cancer Recruiting
NCT07562490 A Randomized Controlled Trial of Plasma ctDNA Methylation-Guided Adjuvant Chemotherapy… ctDNA Recruiting
NCT07562711 Randomized Study of Plasma ctDNA Methylation to Guide Adjuvant Chemotherapy Decisions in… ctDNA Recruiting
NCT05702229 Novel Combinations in Participants With Locally Advanced Unresectable or Metastatic… Gastric Cancer Recruiting
NCT07314528 Evaluating the Impact of GLP-1 Receptor Agonists With Total Neoadjuvant Therapy in Rectal… Rectal Cancer Patients Not Yet Recruiting
NCT06106308 Study of Onvansertib in Combination With FOLFIRI and Bevacizumab or FOLFOX and… Metastatic Colorectal Cancer Active, Not Recruiting
NCT07353827 FOLFOX-HAIC Combined With Donafenib and Pucotenlimab as First-Line Treatment for… Intrahepatic Cholangiocarcinoma (Icc) Not Yet Recruiting
NCT07603375 Upfront Chemotherapy With Radiation Therapy (CRT) Followed by Chemotherapy in Localized… Esophageal Adenocarcinoma Not Yet Recruiting
NCT07622017 KORTUC (KRC-01) Plus Radiotherapy for Organ Preservation in Rectal Cancer Rectal Cancer Not Yet Recruiting
NCT03781323 Neoadjuvant FOLFOX Therapy With Short Course Radiation and Active Surveillance in Locally… Advanced Rectal Cancer Active, Not Recruiting
Phase 1/2
NCT07327229 A Phase Ib/II Study of ATG-022 Plus Pembrolizumab With/Without Chemotherapy in… Unresectable or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma Recruiting
NCT06598007 A Study to Determine the Effect of CT3001 in Patients With Advanced Solid Tumors Solid Tumor, Adult Recruiting
NCT04068610 COLUMBIA-1: Novel Oncology Therapies in Combination With Chemotherapy and Bevacizumab as… Metastatic Microsatellite-stable Colorectal Cancer Active, Not Recruiting
Phase 1
NCT04808323 MRI-Guided Adaptive Radiation Therapy for Organ Preservation in Rectal Cancer Rectal Adenocarcinoma Recruiting
NCT06625775 Open-Label Study of BBO-10203 in Subjects With Advanced Solid Tumors Solid Tumor, Adult Recruiting
Sponsors Running FOLFOX Trials
Disease Areas
Get alerts when FOLFOX trials change
Status changes, date slips, and new filings — detected daily, delivered to your inbox.
Start monitoring free