Drug Pipeline

Enfortumab Vedotin Clinical Trials

Data updated daily from ClinicalTrials.gov — last refresh 2026-06-12
40
Active Studies
29
Recruiting
3
Phase 3
10
Top Sponsors
8
Changes, 30 Days
What Changed in the Last 30 Days
DetectedTrialChange
2026-06-09 NCT07566156
Enfortumab Vedotin in Combination With Pembrolizumab vs. Concurrent Chemoradiotherapy…
Trial sites expanded: 1 -> 9 locations
2026-06-06 NCT07475806
A Study to Find Out if Enfortumab Vedotin Given With Pembrolizumab Helps People With…
Trial sites expanded: 5 -> 9 locations
2026-06-05 NCT07421700
Symbiotic-GU-06: A Study to Learn About PF-08634404 Alone or In Combination With…
Trial sites expanded: 40 -> 50 locations
2026-06-05 NCT04960709
Treatment Combination of Durvalumab, Tremelimumab and Enfortumab Vedotin or Durvalumab…
Trial sites reduced: 202 -> 196 locations
2026-06-05 NCT04960709
Treatment Combination of Durvalumab, Tremelimumab and Enfortumab Vedotin or Durvalumab…
date change Primary completion moved earlier: 2026-04-30 -> 2026-03-02
2026-05-29 NCT06862219
A Safety Study of Enfortumab Vedotin in Indian Adults With Urothelial Cancer
Trial sites expanded: 10 -> 13 locations
2026-05-16 NCT07484022
Study of GB-4362 With Enfortumab Vedotin and Pembrolizumab for Advanced Urothelial Cancer
Trial sites expanded: 2 -> 6 locations
2026-05-16 NCT07475806
A Study to Find Out if Enfortumab Vedotin Given With Pembrolizumab Helps People With…
Trial sites expanded: 1 -> 5 locations
New Trial Filings, Last 30 Days
First PostedTrialPhaseStatus
2026-06-05 NCT07629700 Study of Peripheral Neuropathy in Patients With Advanced Urothelial Cancer Treated With… Not Yet Recruiting
Active Studies by Phase
Phase 4
2
Phase 3
3
Phase 2
22
Phase 1/2
6
Phase 1
4
Not specified
3
Active Trials — top 25 of 40
NCT IDTitleConditionStatus
Phase 4
NCT06764095 Enfortumab Vedotin and Pembrolizumab With Cystectomy and/or Ureterectomy for Locally… Locally Advanced Bladder Urothelial Carcinoma Recruiting
NCT06862219 A Safety Study of Enfortumab Vedotin in Indian Adults With Urothelial Cancer Metastatic Urothelial Carcinoma Recruiting
Phase 3
NCT07566156 Enfortumab Vedotin in Combination With Pembrolizumab vs. Concurrent Chemoradiotherapy… Urothelial Cancer Recruiting
NCT04223856 Enfortumab Vedotin and Pembrolizumab vs. Chemotherapy Alone in Untreated Locally Advanced… Urothelial Cancer Active, Not Recruiting
NCT04960709 Treatment Combination of Durvalumab, Tremelimumab and Enfortumab Vedotin or Durvalumab… Muscle Invasive Bladder Cancer Active, Not Recruiting
Phase 2
NCT05656235 Renal Retention in High Grade Upper Tract Urothelial Cancer High Grade Urothelial Carcinoma Recruiting
NCT05775471 Pembrolizumab and Enfortumab Vedotin With Pembrolizumab Prior to and After Radical… Renal Pelvis and Ureter Urothelial Carcinoma Recruiting
NCT07221942 Pembrolizumab Maintenance After Enfortumab Vedotin (EV)/Pembro Induction in Front-Line… Metastatic Urothelial Carcinoma Recruiting
NCT06809140 Enfortumab Vedotin Plus Pembrolizumab With Selective Bladder Sparing for Treatment of… Muscle Invasive Bladder Urothelial Carcinoma Recruiting
NCT07347314 Enfortumab Vedotin in Patients With Advanced Small Bowel Adenocarcinoma Refractory or… Advanced Small Bowel Adenocarcinoma Recruiting
NCT03547973 Study of Sacituzumab Govitecan in Participants With Urothelial Cancer That Cannot Be… Metastatic Urothelial Cancer Recruiting
NCT06891560 A Study of Enfortumab Vedotin in People With Adenoid Cystic Carcinoma Adenoid Cystic Carcinoma Recruiting
NCT06553885 Ph II Study of Enfortumab Vedotin in Patients With Advanced or Metastatic CRC or HCC Metastatic Colorectal Cancer Recruiting
NCT06145308 Precision Treatment of Recurrent/Metastatic Salivary Gland Carcinoma Guided by Molecular… Salivary Gland Carcinoma Recruiting
NCT07110038 DEPECA-1 - A Phase II Study to Evaluate a First-line Systemic Therapy With Enfortumab… Penile Squamous Cell Carcinoma (PSCC) Recruiting
NCT07087860 Therapeutic Plasma Exchange With Enfortumab Vedotin and Pembrolizumab for Treatment of… Metastatic Bladder Urothelial Carcinoma Recruiting
NCT05868265 A Study of Enfortumab Vedotin in People With Urothelial Carcinoma of the Upper Urinary… Urothelial Carcinoma Recruiting
NCT06041503 Enfortumab Vedotin With or Without Pembrolizumab in Rare Genitourinary Tumors (E-VIRTUE) Adenocarcinoma of the Bladder Recruiting
NCT06311214 Personalized Antibody-Drug Conjugate Therapy Based on RNA and Protein Testing for the… Advanced Malignant Solid Neoplasm Recruiting
NCT05239624 Enfortumab Vedotin and Pembrolizumab in People With Bladder Cancer Urothelial Carcinoma Recruiting
NCT07475806 A Study to Find Out if Enfortumab Vedotin Given With Pembrolizumab Helps People With… Muscle-invasive Bladder Cancer Recruiting
NCT06104618 Enfortumab Vedotin for the Treatment of Patients With Metastatic or Unresectable Squamous… Metastatic Penile Squamous Cell Carcinoma Recruiting
NCT07139977 Study of EV for Recurrent Endometrial Carcinoma Endometrial Cancer Not Yet Recruiting
NCT07374549 SYS6002 vs PADCEV in Patients With Advanced Urothelial Carcinoma Advanced Urothelial Carcinoma Not Yet Recruiting
NCT04754191 Enfortumab Vedotin as Monotherapy in Patients With Metastatic Castration-Resistant… Metastatic Castration-resistant Prostate Cancer Active, Not Recruiting
Sponsors Running Enfortumab Vedotin Trials
Disease Areas
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