| Detected | Trial | Change |
|---|---|---|
| 2026-06-04 | NCT06465199 Eflornithine (DFMO) and AMXT 1501 for Neuroblastoma, CNS Tumors, and Sarcomas |
date change Primary completion pushed: 2033-02 -> 2033-05 |
| 2026-06-04 | NCT06465199 Eflornithine (DFMO) and AMXT 1501 for Neuroblastoma, CNS Tumors, and Sarcomas |
date change Completion pushed: 2035-02 -> 2035-05 |
| 2026-05-27 | NCT07321912 Eflornithine (DFMO) for Ewing Sarcoma and Osteosarcoma |
Recruitment opened |
| NCT ID | Title | Condition | Status |
|---|---|---|---|
| Phase 2 | |||
| NCT06059118 | Difluoromethylornithine and High Dose Testosterone With Enzalutamide in Metastatic… | Prostate Cancer | Recruiting |
| NCT02679144 | Neuroblastoma Maintenance Therapy Trial | Neuroblastoma | Recruiting |
| NCT04301843 | Eflornithine (DFMO) and Etoposide for Relapsed/Refractory Neuroblastoma | Neuroblastoma | Recruiting |
| NCT05594563 | TArgeting Type 1 Diabetes Using POLyamines (TADPOL) | Type 1 Diabetes | Recruiting |
| NCT02559778 | Pediatric Precision Laboratory Advanced Neuroblastoma Therapy | Neuroblastoma | Recruiting |
| NCT04696029 | DFMO as Maintenance Therapy for Molecular High/Very High Risk and Relapsed Medulloblastoma | Medulloblastoma | Recruiting |
| NCT07321912 | Eflornithine (DFMO) for Ewing Sarcoma and Osteosarcoma | Osteosarcoma | Recruiting |
| NCT03794349 | Irinotecan Hydrochloride, Temozolomide, and Dinutuximab With or Without Eflornithine in… | High Risk Neuroblastoma | Active, Not Recruiting |
| Phase 1/2 | |||
| NCT07287917 | Study of AMXT 1501 and DFMO in Combination With Standard Therapies in Advanced Solid… | Melanoma (Skin Cancer) | Recruiting |
| NCT06892678 | DFMO Maintenance for Patients With Relapsed/Refractory Ewing Sarcoma or Osteosarcoma | Osteosarcoma Recurrent | Recruiting |
| NCT06465199 | Eflornithine (DFMO) and AMXT 1501 for Neuroblastoma, CNS Tumors, and Sarcomas | Atypical Teratoid/Rhabdoid Tumor | Recruiting |
| NCT07468136 | Retifanlimab With or Without Difluoromethylornithine for the Treatment of Progressive… | Anaplastic Oligodendroglioma | Not Yet Recruiting |