Drug Pipeline

Cabozantinib Clinical Trials

Data updated daily from ClinicalTrials.gov — last refresh 2026-06-12
73
Active Studies
38
Recruiting
13
Phase 3
10
Top Sponsors
10
Changes, 30 Days
What Changed in the Last 30 Days
DetectedTrialChange
2026-06-12 NCT07383441
Adding Biotherapy or Placebo to Standard Treatment for Advanced Kidney Cancer
Recruitment opened
2026-06-12 NCT07383441
Adding Biotherapy or Placebo to Standard Treatment for Advanced Kidney Cancer
Trial sites expanded: 0 -> 41 locations
2026-06-12 NCT05111574
Using Nivolumab Alone or With Cabozantinib to Prevent Mucosal Melanoma Return After…
overall status: "Recruiting" → "Active Not Recruiting"
2026-06-09 NCT07405164
Extension Study for Participants in Studies That Include Belzutifan…
Trial sites expanded: 15 -> 20 locations
2026-06-06 NCT05168618
Cabozantinib and Atezolizumab for the Treatment of Metastatic Castration-Resistant…
date change Primary completion pushed: 2026-05 -> 2026-07
2026-06-03 NCT07011719
Study of Casdatifan and Cabozantinib Versus Placebo and Cabozantinib in Patients With…
Trial sites expanded: 97 -> 118 locations
2026-05-27 NCT07293351
A Study to Evaluate the Safety, Tolerability, and Efficacy of Pumitamig Alone or in…
Trial arms changed: 10 -> 9
2026-05-16 NCT06475989
Study of Targeted Therapy vs. Chemotherapy in Patients With Thyroid Cancer
Trial sites expanded: 112 -> 301 locations
2026-05-15 NCT07011719
Study of Casdatifan and Cabozantinib Versus Placebo and Cabozantinib in Patients With…
Trial sites expanded: 44 -> 97 locations
2026-05-15 NCT05425004
Cabozantinib for Patients With Recurrent or Progressive Meningioma
date change Primary completion pushed: 2026-10 -> 2026-12
New Trial Filings, Last 30 Days
First PostedTrialPhaseStatus
2026-06-02 NCT07620574 Long-Term Extension Study for Participants Previously Enrolled in an Exelixis-Sponsored… Phase 3 Not Yet Recruiting
Active Studies by Phase
Phase 3
12
Phase 2/3
1
Phase 2
43
Phase 1/2
7
Phase 1
10
Active Trials — top 25 of 73
NCT IDTitleConditionStatus
Phase 3
NCT06475989 Study of Targeted Therapy vs. Chemotherapy in Patients With Thyroid Cancer Refractory Differentiated Thyroid Gland Carcinoma Recruiting
NCT07011719 Study of Casdatifan and Cabozantinib Versus Placebo and Cabozantinib in Patients With… Metastatic Clear Cell Renal Cell Carcinoma Recruiting
NCT07227402 A Clinical Study of Belzutifan and Zanzalintinib in People With Recurrent Kidney Cancer… Renal Cell Carcinoma Recruiting
NCT07405164 Extension Study for Participants in Studies That Include Belzutifan… Von Hippel-Lindau Disease Recruiting
NCT07383441 Adding Biotherapy or Placebo to Standard Treatment for Advanced Kidney Cancer Advanced Clear Cell Renal Cell Carcinoma Recruiting
NCT04211337 A Study of Selpercatinib (LY3527723) in Participants With RET-Mutant Medullary Thyroid… Medullary Thyroid Cancer Active, Not Recruiting
NCT03768063 A Study in Patients Previously Enrolled in a Genentech and/or F. Hoffmann-La Roche Ltd… Cancer Active, Not Recruiting
NCT04586231 A Study of Belzutifan (MK-6482) in Combination With Lenvatinib Versus Cabozantinib for… Carcinoma, Renal Cell Active, Not Recruiting
NCT05092958 Testing the Addition of the Anti-cancer Drug, Cabozantinib, to the Usual Immunotherapy… Advanced Bladder Urothelial Carcinoma Active, Not Recruiting
NCT03793166 Immunotherapy With Nivolumab and Ipilimumab Followed by Nivolumab or Nivolumab With… Clear Cell Renal Cell Carcinoma Active, Not Recruiting
NCT07620574 Long-Term Extension Study for Participants Previously Enrolled in an Exelixis-Sponsored… Cancer Not Yet Recruiting
NCT03375320 Testing Cabozantinib in Patients With Advanced Pancreatic Neuroendocrine and Carcinoid… Functioning Pancreatic Neuroendocrine Tumor Active, Not Recruiting
Phase 2/3
NCT05691478 A Study to Test the Addition of the Drug Cabozantinib to Chemotherapy in Patients With… High Grade Osteosarcoma Recruiting
Phase 2
NCT05613413 A Pilot Phase II Study of Maintenance Cabozantinib Plus Pembrolizumab for Patients With… Metastatic Squamous Non-Small Cell Lung Carcinoma Recruiting
NCT05502315 Study of Cabozantinib and Nivolumab in Metastatic Castration Resistant Prostate Cancer Castration-resistant Prostate Cancer Recruiting
NCT07077161 Cabozantinib Dose Skipping as an Alternative to Dose Reductions Renal Cell Carcinoma (RCC) Recruiting
NCT06006013 Cabozantinib in Combination With Pembrolizumab for the Treatment of Patients With Locally… Locally Advanced Adrenal Cortex Carcinoma Recruiting
NCT05048212 A Phase II Study of Nivolumab With Ipilimumab and Cabozantinib in Patients With Untreated… Brain Metastases Recruiting
NCT05019703 Atezolizumab and Cabozantinib for the Treatment of Adolescents and Young Adults With… Locally Advanced Osteosarcoma Recruiting
NCT04116541 A Study Evaluating the Activity of Anti-cancer Treatments Targeting Tumor Molecular… Malignant Solid Tumor Recruiting
NCT05361720 Genetic Testing to Select Therapy for the Treatment of Advanced or Metastatic Kidney… Advanced Clear Cell Renal Cell Carcinoma Recruiting
NCT04472767 Cabozantinib Combined With Ipilimumab/Nivolumab and TACE in Patients With Hepatocellular… Hepatocellular Carcinoma Recruiting
NCT05327686 Testing the Addition of Stereotactic Radiation Therapy With Immune Therapy for the… Metastatic Renal Cell Carcinoma Recruiting
NCT05425004 Cabozantinib for Patients With Recurrent or Progressive Meningioma Meningioma Recruiting
NCT05904080 Testing Nivolumab and Ipilimumab Immunotherapy With or Without the Targeted Drug… Metastatic Nasopharyngeal Carcinoma Recruiting
Sponsors Running Cabozantinib Trials
Disease Areas
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