Schizophrenia clinical trials
Data updated daily from ClinicalTrials.gov, last refresh 2026-11-05
What changed in the last 30 days
29 trials changed in the last 30 days: 3 stopped, 11 with notable changes, 15 with minor changes only.
- Minor: REACH Study (Recovery Environments: Assessing Cognitive & Brain Health in Community Mental Health) Study completion pushed from Jan 30, 2028 to Jan 30, 2029
- Minor: Neuro-VR · Augmenting a Virtual Reality-based Therapy With Biofeedback for Auditory Hallucinations Trial completed
- Minor: NEURO-COGS · Neurometabolic Mechanisms of Cognitive Training in Schizophrenia Start date pushed from Nov 2, 2026 to Nov 16, 2026
- Minor: Adverse-effect Switch Evaluation of Xanomeline and Trospium Chloride (KarXT) Trial sites expanded: 55 → 68 locations
- Stopped: SHINE · Xanomeline/Trospium (XT) on Cognitive Impairment After 24 and 52 Weeks of Treatment · Schizophrenia Withdrawn before enrolling
- Minor: Aging and Disease Course: Contributions to Lifespan Neurobiology of Schizophrenia Trial completed
- Minor: MST · Motivation Skills Training Trial completed
- Minor: Relapse Prevention Trial Evaluating KarXT Treatment in Schizophrenia Trial sites reduced: 59 → 54 locations
- Notable: dTMS · Relation Between Craving Induction and Treatment Response in Deep Transcranial Magnetic Stimulation (dTMS) for Reducing Antipsychotic-induced Weight Gain in Schizophrenia Recruitment opened
- Minor: KAPPTIVATE1001 · Aticaprant as Adjunctive Treatment · Schizophrenia Study completion pushed from Jul 5, 2027 to Dec 3, 2027
- Notable: dTMS · DTMS for Reducing Antipsychotic-induced Weight Gain Recruitment opened
- Notable: HHK101 · Schizophrenia Start date pushed from Sep 30, 2026 to Nov 15, 2026
- Notable: IEvaEcoSchi · Interest of the Tool: Evaluation of Specific Care in an Ecological Environment · Schizophrenia-like Disorders Primary and study completion pushed from Feb 2026 to Feb 2027
- Minor: KYN-5356 · Cognitive Impairment Associated With Schizophrenia Trial completed
- Notable: VIRTUS · Reducing Mental Health Stigmatization Among Healthcare Workers and Students Using a Virtual Reality Protocol: The VIRTUS Protocol Recruitment opened
- Minor: Brain Imaging of Childhood Onset Psychiatric Disorders, Endocrine Disorders and Healthy Volunteers Trial completed
- Minor: KarXT on Urological Safety Trial sites expanded: 13 → 16 locations
- Stopped: Normobaric Oxygen Therapy · First-Episode Psychosis Trial terminated
- Notable: Detect the Radioactivity of 14C-SEP-380135 in Urine and Feces in Healthy Male Adults Primary and study completion dates pushed to Dec 2, 2026
- Notable: Quality of Life, Safety and Compliance of Patients Using Monotherapy or Combinatorial Therapy With Quetiapine · Schizophrenia or Bipolar Affective Disorder Primary endpoint(s) modified
- Stopped: terminated, suspended or withdrawn
- Notable: the plan changed
- Minor: routine updates
New sponsor entrants, last 90 days sponsors with their first trial in this area
| First posted | Trial | Sponsor | Phase |
|---|---|---|---|
| 2026-11-04 | NCT07917637 Ashwagandha Added to Risperidone for Quality of Life and Inflammation in Schizophrenia | Athitah Pratiwi new | |
| 2026-10-19 | NCT07881016 French Minds Cohort: a French Longitudinal and Multimodal Cohort of Patients With Major… | Fondation FondaMental new | |
| 2026-10-16 | NCT07879118 Effect of Occupational Therapy on Psychosocial Parameters and Functioning in Individuals… | Biruni University new | |
| 2026-10-15 | NCT07876089 Validation and Comparative Multi-Omics Benchmarking of Fluid-Derived Volatilomics… | University Hospital, Aachen new | |
| 2026-10-09 | NCT07867964 Feasibility Trial of a Parent Peer-Co-Led Caregiver Group for Pediatric Early Onset… | Boston Children's Hospital new | |
| 2026-10-05 | NCT07858565 Quality of Life, Safety and Compliance of Patients Using Monotherapy or Combinatorial… | Bosnalijek D.D new | |
| 2026-10-01 | NCT07853079 Motivational Intervention for Patients With Schizophrenia | University of Geneva, Switzerland new | |
| 2026-09-25 | NCT07843056 A Clinical Trial to Compare the Efficacy and Safety of WAS123 Versus Daily Aripiprazole… | EMS new | Phase 2 |
| 2026-09-14 | NCT07818668 tACS for Self-Other Boundary in Schizophrenia | Chunyan Zhu new | |
| 2026-09-14 | NCT07817069 Effects of Nitraria Retusa Infusion on Clozapine-induced Metabolic Side Effects | Faculty of Medicine, Sousse new |
Active trials by phase
| Early Phase 1 | 4 | |
| Phase 1 | 20 | |
| Phase 1/2 | 11 | |
| Phase 2 | 36 | |
| Phase 2/3 | 5 | |
| Phase 3 | 32 | |
| Phase 4 | 24 |
Not charted: 377 active trials with no phase listed on ClinicalTrials.gov (typically behavioural, device, procedure and observational studies).
Top sponsors by active trials in this area
Shanghai Mental Health Center (13) · Centre for Addiction and Mental Health (12) · Central South University (9) · China Medical University Hospital (8) · The University of Texas Health Science Center, Houston (8) · Bristol-Myers Squibb (7) · University Hospital, Strasbourg, France (7) · VA Office of Research and Development (7) · Hôpital le Vinatier (6) · King's College London (6)
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