| Detected | Trial | Change |
|---|---|---|
| 2026-08-13 | NCT07697586 SKB264 in Combination With SKB118 for Non-Small Cell Lung Cancer |
Recruitment opened |
| 2026-08-13 | NCT07324629 Sacituzumab Tirumotecan in Participants With Locally Advanced or Metastatic Thymic… |
Recruitment opened |
| 2026-08-05 | NCT07564466 A Study of SKB571 in Participants With Gastrointestinal Tumors |
Recruitment opened |
| 2026-08-05 | NCT05906537 SKB410 for Injection in Solid Tumors |
Trial completed |
| 2026-08-05 | NCT05906537 SKB410 for Injection in Solid Tumors |
Enrollment reduced: 54 -> 38 participants |
| 2026-08-05 | NCT05906537 SKB410 for Injection in Solid Tumors |
date change Primary completion moved earlier: 2026-12-30 -> 2026-03-31 |
| 2026-08-05 | NCT05906537 SKB410 for Injection in Solid Tumors |
date change Completion moved earlier: 2026-12-30 -> 2026-03-31 |
| 2026-08-01 | NCT07545265 SKB565 for Injection in Advanced Solid Tumors |
date change Primary completion pushed: 2028-12 -> 2029-03 |
| 2026-08-01 | NCT07545265 SKB565 for Injection in Advanced Solid Tumors |
date change Completion pushed: 2029-05 -> 2029-08 |
| 2026-07-31 | NCT07308106 A Phase II Clinical Study of SKB571 as Monotherapy in Patients With Locally Advanced or… |
Enrollment increased: 60 -> 70 participants |
| First Posted | Trial | Phase | Status |
|---|---|---|---|
| 2026-07-28 | NCT07732023 A Randomized, Phase Ib, Double-Blind, Placebo-Controlled Study to Evaluate the Safety and… | Phase 1 | Not Yet Recruiting |
| NCT ID | Title | Condition | Status |
|---|---|---|---|
| Phase 3 | |||
| NCT06081959 | Study of SKB264 for Locally Advanced, Recurrent or Metastatic HR+/HER2- Breast Cancer | Metastatic Breast Cancer | Recruiting |
| NCT06279364 | A Study of SKB264 Versus Investigator's Choice Chemotherapy in Patients With Unresectable… | Triple Negative Breast Cancer | Recruiting |
| NCT07071337 | A Study of SKB264 Versus Investigator's Choice of Chemotherapy in Subjects With… | Metastatic Breast Cancer | Recruiting |
| NCT05294172 | KL-A167 Injection Combined With Cisplatin and Gemcitabine vs Placebo Combined With… | Nasopharyngeal Carcinoma | Active, Not Recruiting |
| NCT05347134 | SKB264 Injection vs Investigator Selected Regimens to Treat Locally Advanced, Recurrent… | Triple Negative Breast Cancer | Active, Not Recruiting |
| NCT05870319 | A Phase III Study of SKB264 for EGFR Mutant NSCLC Patients | Non-small Cell Lung Cancer | Active, Not Recruiting |
| NCT06448312 | A Study of SKB264 in Combination With Pembrolizumab Versus Pembrolizumab in Patients With… | Non-Small Cell Lung Cancer | Active, Not Recruiting |
| NCT06968585 | A Study of A166 Versus Trastuzumab Emtansine (T-DM1) in Patients With HER2-Positive… | HER2-positive Breast Cancer | Active, Not Recruiting |
| NCT06711900 | A Study of SKB264 in Combination With Pembrolizumab Versus Chemotherapy in Combination… | Non-Small Cell Lung Cancer | Active, Not Recruiting |
| NCT06670196 | A Study of SKB264 in Combination With Osimertinib Versus Osimertinib in Patients With… | Non-Small Cell Lung Cancer | Active, Not Recruiting |
| Phase 2 | |||
| NCT07019675 | A Study of SKB518 in Patients With Lung Cancer | Lung Carcinoma | Recruiting |
| NCT07296809 | SKB500 Combinations in Patients With Small Cell Lung Cancer | Small Cell Lung Cancer | Recruiting |
| NCT07299825 | A Study of A166 in Patients With HER2-Positive Unresectable or Metastatic Breast Cancer | Her 2 Positive Breast Cancer | Recruiting |
| NCT07329322 | Phase II Study of Sacituzumab Tirumotecan in Combination With Osimertinib or Sacituzumab… | Non-Small Cell Lung Cancer | Recruiting |
| NCT05351788 | SKB264 Combinatiton Therapy in Patients With Advanced or Metastatic Non-small Cell Lung… | Non-small Cell Lung Cancer | Recruiting |
| NCT07230405 | A Phase II Study of SKB571 in Patients With Lung Cancer | Lung Cancer (Non-Small Cell) | Recruiting |
| NCT07448922 | A Study of SKB518 as Monotherapy or Combination Therapy in Patients With Advanced… | Advanced Gynecological Malignancies | Recruiting |
| NCT07308106 | A Phase II Clinical Study of SKB571 as Monotherapy in Patients With Locally Advanced or… | Non-small Lung Cancer | Recruiting |
| NCT07564466 | A Study of SKB571 in Participants With Gastrointestinal Tumors | Gastrointestinal Tumors | Recruiting |
| NCT07324629 | Sacituzumab Tirumotecan in Participants With Locally Advanced or Metastatic Thymic… | Thymic Carcinoma | Recruiting |
| NCT07697586 | SKB264 in Combination With SKB118 for Non-Small Cell Lung Cancer | NSCLC | Recruiting |
| NCT05445908 | SKB264 +/- KL-A167 in Recurrent or Metastatic HER2-negative Breast Cancer | Triple-negative Breast Cancer and HR+/HER2- BC | Active, Not Recruiting |
| NCT05631262 | SKB264 Monotherapy in Selected Subjects With Advanced Solid Tumors | Selected Subjects With Advanced Solid Tumors | Active, Not Recruiting |
| NCT07609667 | SKB315 in Combination Therapy in Patients With Advanced or Metastatic GC/ GEJ… | Gastroesophageal Junction Adenocarcinoma | Not Yet Recruiting |
| NCT07341100 | Study to Evaluate the Preliminary Efficacy of SKB264 and the Effect of Clarithromycin on… | Ovarian Epithelial Cancer | Active, Not Recruiting |