44 active trials 30 recruiting 10 Phase 3 12 disease areas 2 changes in 30 days
1 trial changed in the last 30 days: 0 stopped, 0 with notable changes, 1 with a minor change only.
Trial completed
Also in this update: Primary completion date changed from estimate of Jun 30, 2026 to Apr 9, 2026
Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd.Phase 1 NCT05311397 Registry history of NCT05311397 on ClinicalTrials.gov (opens the registry)
Updated
| First posted | Trial | Phase | Status |
|---|---|---|---|
| 2026-10-02 | NCT07854509 A Phase II Study of SKB264 + SKB118 in Nsq-NSCLC After EGFR-TKI Failure | Phase 2 | Not Yet Recruiting |
| Phase 1 | 9 | |
| Phase 1/2 | 6 | |
| Phase 2 | 19 | |
| Phase 3 | 10 |
| NCT ID | Title | Condition | Status | Updated |
|---|---|---|---|---|
| Phase 3 | ||||
| NCT06081959 | Study of SKB264 for Locally Advanced, Recurrent or Metastatic HR+/HER2- Breast Cancer | Metastatic Breast Cancer | Recruiting | 2026-05-08 |
| NCT06279364 | A Study of SKB264 Versus Investigator's Choice Chemotherapy in Patients With Unresectable… | Triple Negative Breast Cancer | Recruiting | 2026-05-08 |
| NCT07071337 | A Study of SKB264 Versus Investigator's Choice of Chemotherapy in Subjects With… | Metastatic Breast Cancer | Recruiting | 2026-05-08 |
| NCT06670196 | A Study of SKB264 in Combination With Osimertinib Versus Osimertinib in Patients With… | Non-Small Cell Lung Cancer | Active, Not Recruiting | 2026-07-10 |
| NCT06711900 | A Study of SKB264 in Combination With Pembrolizumab Versus Chemotherapy in Combination… | Non-Small Cell Lung Cancer | Active, Not Recruiting | 2026-07-08 |
| NCT05294172 | KL-A167 Injection Combined With Cisplatin and Gemcitabine vs Placebo Combined With… | Nasopharyngeal Carcinoma | Active, Not Recruiting | 2026-05-08 |
| NCT05347134 | SKB264 Injection vs Investigator Selected Regimens to Treat Locally Advanced, Recurrent… | Triple Negative Breast Cancer | Active, Not Recruiting | 2026-05-08 |
| NCT05870319 | A Phase III Study of SKB264 for EGFR Mutant NSCLC Patients | Non-small Cell Lung Cancer | Active, Not Recruiting | 2026-05-08 |
| NCT06448312 | A Study of SKB264 in Combination With Pembrolizumab Versus Pembrolizumab in Patients With… | Non-Small Cell Lung Cancer | Active, Not Recruiting | 2026-05-08 |
| NCT06968585 | A Study of A166 Versus Trastuzumab Emtansine (T-DM1) in Patients With HER2-Positive… | HER2-positive Breast Cancer | Active, Not Recruiting | 2026-05-08 |
| Phase 2 | ||||
| NCT07668154 | A Phase II Study to Evaluate the Efficacy and Safety of SKB571 in Recurrent or Metastatic… | HNSCC | Recruiting | 2026-09-09 |
| NCT07622186 | A Study of SKB571 Combination Therapy in Participants With Non-Small Cell Lung Cancer… | Non-Small Cell Lung Cancer | Recruiting | 2026-09-02 |
| NCT07700667 | SKB500 Combinations in Patients With Esophageal Squamous Cell Carcinoma | Esophageal Squamous Cell Carcinoma | Recruiting | 2026-08-26 |
| NCT07329322 | Phase II Study of Sacituzumab Tirumotecan in Combination With Osimertinib for Neoadjuvant… | Non-Small Cell Lung Cancer | Recruiting | 2026-08-20 |
| NCT07324629 | Sacituzumab Tirumotecan in Participants With Locally Advanced or Metastatic Thymic… | Thymic Carcinoma | Recruiting | 2026-08-12 |
| NCT07697586 | SKB264 in Combination With SKB118 for Non-Small Cell Lung Cancer | NSCLC | Recruiting | 2026-08-12 |
| NCT07564466 | A Study of SKB571 in Participants With Gastrointestinal Tumors | Gastrointestinal Tumors | Recruiting | 2026-08-04 |
| NCT07308106 | A Phase II Clinical Study of SKB571 as Monotherapy in Patients With Locally Advanced or… | Non-small Lung Cancer | Recruiting | 2026-07-30 |
| NCT05351788 | SKB264 Combinatiton Therapy in Patients With Advanced or Metastatic Non-small Cell Lung… | Non-small Cell Lung Cancer | Recruiting | 2026-05-12 |
| NCT07230405 | A Phase II Study of SKB571 in Patients With Lung Cancer | Lung Cancer (Non-Small Cell) | Recruiting | 2026-05-12 |
| NCT07448922 | A Study of SKB518 as Monotherapy or Combination Therapy in Patients With Advanced… | Advanced Gynecological Malignancies | Recruiting | 2026-05-12 |
| NCT07019675 | A Study of SKB518 in Patients With Lung Cancer | Lung Carcinoma | Recruiting | 2026-05-08 |
| NCT07296809 | SKB500 Combinations in Patients With Small Cell Lung Cancer | Small Cell Lung Cancer | Recruiting | 2026-05-08 |
| NCT07299825 | A Study of A166 in Patients With HER2-Positive Unresectable or Metastatic Breast Cancer | Her 2 Positive Breast Cancer | Recruiting | 2026-05-08 |
| NCT07854509 | A Phase II Study of SKB264 + SKB118 in Nsq-NSCLC After EGFR-TKI Failure | Non-Squamous Non-Small Cell Lung Cancer | Not Yet Recruiting | 2026-10-02 |
Lung Cancer (12) · Non-Small Cell Lung Cancer (NSCLC) (11) · Breast Cancer (7) · Head & Neck Cancer (2) · Triple-Negative Breast Cancer (2) · Asthma (1) · Atopic Dermatitis (1) · Esophageal Cancer (1) · HER2-Positive Cancer (1) · Ovarian Cancer (1)