SWOG Cancer Research Network clinical trial pipeline

14 trials changed in the last 30 days: 0 stopped, 5 with notable changes, 9 with minor changes only.

1. Notable

   Standard Systemic Therapy With or Without Definitive Treatment…Standard Systemic Therapy With or Without Definitive Treatment · Metastatic Prostate Cancer

   Primary completion pushed from Apr 1, 2028 to Apr 1, 2033

   Also in this update: Study completion pushed from Oct 1, 2031 to Oct 1, 2036

   SWOG Cancer Research Network·Phase 3· NCT03678025· Registry history of NCT03678025 on ClinicalTrials.gov (opens the registry)

   Oct 8, 2026

2. Notable

   Adding Pirtobrutinib to the Usual Treatment · Newly Diagnosed…Adding Pirtobrutinib to the Usual Treatment · Newly Diagnosed Richter Transformation, The PIRAMID Trial

   Recruitment opened

   Also in this update: Trial sites expanded: 0 → 62 locations

   SWOG Cancer Research Network·Phase 3· NCT07220187· Registry history of NCT07220187 on ClinicalTrials.gov (opens the registry)

   Oct 13, 2026

3. Notable

   Short-Course Radiation Versus Standard-Course Radiation for Soft…Short-Course Radiation Versus Standard-Course Radiation for Soft Tissue Sarcomas That Need Surgery and Radiation

   Recruitment opened

   Also in this update: Trial sites expanded: 0 → 67 locations

   SWOG Cancer Research Network·Phase 3· NCT07615049· Registry history of NCT07615049 on ClinicalTrials.gov (opens the registry)

   Oct 13, 2026

4. Notable

   Adding Surgery and Radiation to the Usual Treatment for…Adding Surgery and Radiation to the Usual Treatment for HER2-Positive Breast Cancer That Had Already Spread at Diagnosis

   Recruitment opened

   Also in this update: Trial sites expanded: 0 → 59 locations

   SWOG Cancer Research Network·Phase 3· NCT07578116· Registry history of NCT07578116 on ClinicalTrials.gov (opens the registry)

   Oct 13, 2026

5. Notable

   Treatment for Advanced Non-small Cell Lung Cancer With Actionable…Treatment for Advanced Non-small Cell Lung Cancer With Actionable Genomic Alterations After Targeted Treatment and Chemotherapy (An Expanded Lung-MAP Treatment Trial)

   Recruitment opened

   Also in this update: Trial sites expanded: 0 → 41 locations

   SWOG Cancer Research Network·Phase 2· NCT07393555· Registry history of NCT07393555 on ClinicalTrials.gov (opens the registry)

   Oct 13, 2026

• Stopped: an ongoing trial was terminated, suspended or withdrawn.
• Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
• Minor: routine progress and housekeeping, such as sites added or enrollment closed.