| Detected | Trial | Change |
|---|---|---|
| 2026-08-01 | NCT07227350 L19IL2 or L19TNF or L19IL2/TNF in Patients With Basal Cell Carcinoma (BCC) |
Trial sites expanded: 3 -> 18 locations |
| 2026-07-22 | NCT07228442 L19IL2/L19TNF in Patients With Cutaneous Squamous Cell Carcinoma |
Recruitment opened |
| 2026-07-22 | NCT07228442 L19IL2/L19TNF in Patients With Cutaneous Squamous Cell Carcinoma |
Trial sites expanded: 2 -> 19 locations |
| 2026-07-22 | NCT07227870 L19IL2/TNF in Patients With Basal Cell Carcinoma |
Recruitment opened |
| 2026-07-22 | NCT07227870 L19IL2/TNF in Patients With Basal Cell Carcinoma |
Trial sites expanded: 3 -> 18 locations |
| NCT ID | Title | Condition | Status |
|---|---|---|---|
| Phase 3 | |||
| NCT03567889 | Efficacy of Daromun Neoadjuvant Intratumoral Treatment in Clinical Stage IIIB/C/D… | Melanoma Stage IIIB | Recruiting |
| NCT02938299 | Neoadjuvant L19IL2/L19TNF- Pivotal Study | Malignant Melanoma | Active, Not Recruiting |
| Phase 2 | |||
| NCT06284590 | Study of the Efficacy of Intratumoral L19IL2 or L19TNF or L19IL2/L19TNF, in Combination… | Melanoma Stage III | Recruiting |
| NCT07227870 | L19IL2/TNF in Patients With Basal Cell Carcinoma | Locally Advanced Basal Cell Carcinoma | Recruiting |
| NCT07228442 | L19IL2/L19TNF in Patients With Cutaneous Squamous Cell Carcinoma | Locally Advanced Cutaneous Squamous Cell Carcinoma | Recruiting |
| NCT07227350 | L19IL2 or L19TNF or L19IL2/TNF in Patients With Basal Cell Carcinoma (BCC) | Locally Advanced Basal Cell Carcinoma | Recruiting |
| NCT04733183 | Efficacy and Safety of L19TNF in Previously Treated Patients with Advanced Stage or… | Soft Tissue Sarcoma | Active, Not Recruiting |
| NCT07120984 | A Study to Evaluate the Safety and Efficacy of L19TNF With Alkylating Chemotherapy for… | Glioma | Not Yet Recruiting |
| NCT06336291 | A Study With L19TNF in Combination With Lomustine in Patients With Glioblastoma at… | Glioblastoma | Active, Not Recruiting |
| Phase 1/2 | |||
| NCT04443010 | Safety and Efficacy of L19TNF Plus Temozolomide Chemoradiotherapy in Patients With Newly… | Glioblastoma | Recruiting |
| Phase 1 | |||
| NCT04471987 | Safety and Early Signs of Efficacy of IL12-L19L19. | Advanced Solid Tumor | Recruiting |
| NCT06640413 | A Study to Evaluate the Safety and Preliminary Signs of Efficacy of [177Lu]Lu-OncoFAP-23… | FAP | Recruiting |
| NCT07600554 | A Phase I Study to Evaluate the Safety and Dosimetry of Imaging With 68Ga-OncoACP3 in… | Prostate Cancer | Recruiting |
| NCT07245992 | A Study of F8IL10 Intra-articular Treatment in Rheumatoid Arthritis | Rheumatoid Arthritis (RA) | Recruiting |
| NCT07566897 | A Phase I Study to Evaluate the Safety and Efficacy of L19IL2 in Combination With… | Renal Carcinoma Metastatic | Not Yet Recruiting |