Clinical Trial

A Study With L19TNF in Combination With Lomustine in Patients With Glioblastoma at Progression or Recurrence

Study acronym: GLIOSTELLA
Active, Not Recruiting Phase 2
View on ClinicalTrials.gov →
Record status
This record was last updated April 21, 2026 (before its estimated June 2026 completion). Its status may not reflect the trial's current state.
Summary
The trial aims to collect safety, efficacy, exposure, dose- response, pharmacokinetic and pharmacodynamic information of the combination of L19TNF and lomustine at different dose levels in patients with Glioblastoma at progression or recurrence
Protocol Amendment History 3 amendments
This ClinicalTrials.gov record has been amended 3 times since 2024-03-21; most recent amendment 2026-04-16.
Status change: Recruiting → Active, Not Recruiting 2026-04-16
Status change: Not Yet Recruiting → Recruiting 2025-01-21
Trial Details
NCT Number NCT06336291
Lead Sponsor Philogen S.p.A.
Conditions Glioblastoma
Enrollment 90 participants
Start Date 2024-05-22
Primary Completion 2026-06 (estimated)
Study Completion 2026-06 (estimated)
Updated on ClinicalTrials.gov 2026-04-21