Disease landscape

Rheumatoid Arthritis clinical trials

Get alerts when Rheumatoid Arthritis trials change

415 active trials 218 recruiting 22 Phase 3 270 sponsors 26 changes in 30 days

Data updated daily from ClinicalTrials.gov, last refresh 2026-08-28

What changed in the last 30 days

2026-08-20
Primary completion pushed: 2027-02-28 → 2027-07-28
Completion pushed: 2027-02-28 → 2027-07-28
NCT05277025 Pain Processing in Inflammatory and Non-Inflammatory Chronic Pain Syndromes · University of Florida
2026-08-20
Trial completed
Completion moved earlier: 2026-02 → 2025-10-15
NCT05533372 MAD Study of IA-14069 · ILAb Co., Ltd. · Phase 1
2026-08-15
Trial completed
NCT05814627 Study to Assess Change in Disease Activity and Adverse Events of Oral Upadacitinib… · AbbVie · Phase 3
2026-08-04
Enrollment closed, study ongoing
Trial sites reduced: 54 → 46 locations
NCT05869955 A Study of CC-97540, CD-19-Targeted Nex-T CAR T Cells, in Participants With Severe… · Juno Therapeutics, Inc., a Bristol-Myers Squibb Company · Phase 1
2026-07-30
Recruitment opened
NCT07564154 A First-in-human Study of KT502 in Adult Participants With Rheumatoid Arthritis (RA) · Kali Therapeutics, Inc. · Phase 1
2026-08-28
Trial completed
Primary completion moved earlier: 2026-04 → 2026-03-02
Completion moved earlier: 2026-04 → 2026-03-02
NCT06666452 COMFI - a COMbined Fatigue Intervention · The Danish Center for Expertise in Rheumatology
2026-08-27
Enrolling by invitation only
NCT07188285 Mass Spectrometry-based Immune Profiling in Autoimmune Diseases · Peking University People's Hospital
2026-08-18
Recruitment opened
NCT07627893 Complementary Herbal Approach to Rheumatoid Management Study (CHARMS) · Singapore General Hospital · Phase 2/3
2026-08-21
Enrollment reopened
NCT07774507 Twenty-four Hour Movement Behaviors and Atherosclerotic Risk · São Paulo State University
2026-08-08
Recruitment opened
Trial sites expanded: 0 → 24 locations
NCT06687551 JAK Inhibitor Dose TAPering Strategy Study · University Hospital, Toulouse · Phase 4
2026-08-26
Trial sites expanded: 56 → 63 locations
NCT07137598 A Study to Assess the Efficacy and Safety of RO7790121 in Participants With Moderate to… · Hoffmann-La Roche · Phase 2
2026-08-22
Trial sites expanded: 6 → 10 locations
NCT07473154 Controlling Hyperactive Immunity With Long-lived Lymphocytes · Quell Therapeutics Limited · Phase 1/2
2026-08-22
Trial sites expanded: 6 → 9 locations
NCT07620392 An Extension Study to Assess Long-Term Safety and Efficacy of Afimkibart in Participants… · Hoffmann-La Roche · Phase 2
2026-07-31
Trial sites expanded: 53 → 72 locations
NCT06712628 A Comparison Study of Persistence of UPadacitinib vs. TNF-inhibitoRs In a German… · AbbVie
2026-08-02
Trial status changed: Not Yet Recruiting → Unknown
NCT06540573 The Relationship Between Serum Chemokine Ligand 21 (CCL-21) Level and Disease Activity · Gaziosmanpasa Research and Education Hospital
2026-08-02
Trial status changed: Recruiting → Unknown
NCT06527534 Filgotinib Effect on Proteomic Profile and Micro-RNA Expression in Patients With Active… · Universita di Verona · Phase 4
2026-08-09
Trial status changed: Not Yet Recruiting → Unknown
NCT06309030 Clinical Study on the Deep Remission of Rheumatoid Arthritis With Kidney Deficiency and… · Liu Longxiao
2026-08-09
Trial status changed: Not Yet Recruiting → Unknown
NCT05570513 Relation of IL23R and IL17A Gene Polymorphisms Plus Serum Levels of IL23 and IL17A to… · Assiut University
2026-08-02
Trial status changed: Not Yet Recruiting → Unknown
NCT06515769 Use of Thermography for the Prevention and Diagnosis of Rheumatic Foot · University of Seville
2026-08-02
Trial status changed: Not Yet Recruiting → Unknown
NCT06514443 Barriers and Faciliators for Physical Activity in People With RMDs · Anne-Kathrin Rausch

New sponsor entrants, last 90 days sponsors with their first trial in this area

First postedTrialSponsorPhase
2026-08-21 NCT07779616 Study of PTC844 in Participants With Active Rheumatoid Arthritis PTC Therapeutics new Phase 2
2026-08-19 NCT07774507 Twenty-four Hour Movement Behaviors and Atherosclerotic Risk São Paulo State University new
2026-08-18 NCT07769619 Integrative AI-Based Multiomic and Neurophysiological Profiling of Chronic Pain in… 4th Military Clinical Hospital with Polyclinic, Poland new
2026-08-12 NCT07760662 Oxidative Stress and Cardiovascular Risk in Patients With Rheumatoid Arthritis University of La Laguna new
2026-07-31 NCT07740200 Validation of the Synovo Digital Disease Activity Score (DDAS) Against… Synovo Ltd. new
2026-07-30 NCT07737119 Impact of Optimised Protein Intake on Household Work Limitations and Disability in… Satguru Partap Singh Hospitals new
2026-07-28 NCT07729995 BAFF CAR-T Cells (LMY-922) for Treatment of Refractory Autoimmune Disease Luminary Therapeutics new Phase 1
2026-07-24 NCT07726355 A Randomized Clinical Trial Evaluating the Efficacy of Clinical Pharmacist Assistance… Deraya University new Phase 2/3
2026-07-22 NCT07721142 Integrated Clinical Study of Traditional Chinese and Western Medicine for Refractory… Shanghai Guanghua Hospital of Integrated Traditional Chinese and Western Medicine new Phase 4
2026-07-20 NCT07715045 Umbilical Cord Mesenchymal Stromal Cell Secretome for Moderate Rheumatoid Arthritis: A… Universitas Sriwijaya new Phase 2

Active trials by phase

Early Phase 1
8
Phase 1
46
Phase 1/2
11
Phase 2
43
Phase 2/3
4
Phase 3
18
Phase 4
29
Not charted: 256 active trials with no phase listed on ClinicalTrials.gov (typically behavioural, device, procedure and observational studies).

Active trials top 25 of 415

NCT IDTitleSponsorStatusUpdated
Phase 4
NCT06687551 JAK Inhibitor Dose TAPering Strategy Study University Hospital, Toulouse Recruiting 2026-08-07
NCT07721142 Integrated Clinical Study of Traditional Chinese and Western Medicine for Refractory… Shanghai Guanghua Hospital of Integrated Traditional Chinese and Western Medicine Recruiting 2026-07-22
NCT07087912 Safety and Immunogenicity of the Live Attenuated Tetravalent Butantan-Dengue Vaccine in… University of Sao Paulo General Hospital Recruiting 2026-07-20
NCT07611747 Carotid Ultrasound-Based Strategy for Primary Prevention of Cardiovascular Events in… Instituto de Investigación Marqués de Valdecilla Recruiting 2026-05-28
NCT07554820 Major Adverse Cardiovascular Events (MACE) in Rheumatoid Arthritis Patient With Moderate… Shaikh Zayed Hospital, Lahore Recruiting 2026-04-28
NCT07245732 Oral Versus Intramuscular Steroid Use to Control Rheumatoid Arthritis Flares Sunnybrook Health Sciences Centre Recruiting 2026-04-13
NCT05955066 Effect of JAK Inhibitor on Erosion Healing in RA Chinese University of Hong Kong Recruiting 2025-12-04
NCT07160231 REDO-JAK: Dose Reduction of Janus Kinase Inhibitors in Patients With Inflammatory… Sint Maartenskliniek Recruiting 2025-09-17
NCT04985435 Better After CHoosing. Randomly Allocated or Patient Preference Based Treatment With… R.Bos Recruiting 2025-08-08
NCT06906549 Evaluation of 200 mg of Rituximab Every 6 Months as Maintenance Treatment of… University Hospital, Strasbourg, France Recruiting 2025-07-23
NCT06003283 Tapering of Rituximab Based on Interval Prolongation Compared to Disease Activity-guided… Universitaire Ziekenhuizen KU Leuven Recruiting 2025-05-31
NCT06913907 Changes in MTX-PG Concentrations During Subcutaneous MTX Therapy in Patients With… Keio University Recruiting 2025-04-06
NCT02714634 Clinical Trial Evaluating Methotrexate or Leflunomide + Targeted Therapy Versus… University Hospital, Strasbourg, France Recruiting 2025-03-12
NCT05540938 Post-marketing Re-evaluation of WangBi Granules for Rheumatoid Arthritis China-Japan Friendship Hospital Recruiting 2025-01-20
NCT03976245 Advanced Therapeutics in Rheumatoid Arthritis (RA) London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's Recruiting 2024-11-29
NCT06649136 MethMax Trial: MAXimising the METHotrexate Therapy Potential in Patients with Active… Medical University of Vienna Recruiting 2024-10-18
NCT06440629 Effect of Proactive Therapeutic Drug Monitoring on Maintenance of Sustained Disease… Diakonhjemmet Hospital Active, Not Recruiting 2026-07-01
NCT07643038 Treatment Strategy for Patients With RA-ILD Chinese SLE Treatment And Research Group Not Yet Recruiting 2026-06-11
NCT07636057 Comparison of Effectiveness and Safety of Tofacitinib Versus Upadacitinib as Add-on to… Sheikh Zayed Federal Postgraduate Medical Institute Not Yet Recruiting 2026-06-09
NCT07582185 Tdose Binding and Tocilizumab Centre Hospitalier Universitaire de Nice Not Yet Recruiting 2026-05-12
NCT05879419 Recombinant Herpes Zoster Vaccine in Patients With Autoimmune Rheumatic Diseases University of Sao Paulo General Hospital Active, Not Recruiting 2026-05-04
NCT07452445 Efficacy and Safety of Ivarmacitinib Monotherapy in the Treatment of csDMARDs-IR… Tongji Hospital Not Yet Recruiting 2026-03-05
NCT07357649 Baricitinib Effects on Procoagulant State in Rheumatoid Arthritis Tanta University Not Yet Recruiting 2026-01-22
NCT07227428 Comparison of Glucocorticoid Tapering Schedules in Rheumatoid Arthritis Seoul National University Hospital Not Yet Recruiting 2025-11-25
NCT07008196 Telitacicept for the Treatment of Refractory RA Chinese SLE Treatment And Research Group Not Yet Recruiting 2025-06-06
See all 415 active Rheumatoid Arthritis trials with filters →

Top sponsors by active trials in this area

Zimmer Biomet (24) · Assiut University (15) · Medacta International SA (6) · Sohag University (6) · Tanta University (6) · Ain Shams University (5) · Diakonhjemmet Hospital (5) · University Hospital, Strasbourg, France (5) · AbbVie (4) · Aesculap AG (4)

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