| Detected | Trial | Change |
|---|---|---|
| 2026-08-05 | NCT07221500 A Study of NX-5948 in Adults With CLL/SLL Previously Treated With a Bruton's Tyrosine… |
Trial sites expanded: 32 -> 35 locations |
| 2026-07-29 | NCT06717269 A Single and Multiple Ascending Doses, Relative Bioavailability, Food Effect, and… |
Trial completed |
| 2026-07-29 | NCT06717269 A Single and Multiple Ascending Doses, Relative Bioavailability, Food Effect, and… |
Primary endpoint(s) modified |
| 2026-07-29 | NCT06717269 A Single and Multiple Ascending Doses, Relative Bioavailability, Food Effect, and… |
Enrollment increased: 18 -> 223 participants |
| 2026-07-29 | NCT06717269 A Single and Multiple Ascending Doses, Relative Bioavailability, Food Effect, and… |
Trial arms changed: 2 -> 7 |
| 2026-07-29 | NCT06717269 A Single and Multiple Ascending Doses, Relative Bioavailability, Food Effect, and… |
date change Primary completion pushed: 2026-04 -> 2026-05-01 |
| 2026-07-29 | NCT06717269 A Single and Multiple Ascending Doses, Relative Bioavailability, Food Effect, and… |
date change Completion moved earlier: 2026-08 -> 2026-05-01 |
| NCT ID | Title | Condition | Status |
|---|---|---|---|
| Phase 3 | |||
| NCT07516093 | Study of NX-5948 Versus Pirtobrutinib in R/R CLL/SLL | B-cell Lymphoma | Not Yet Recruiting |
| Phase 2 | |||
| NCT07221500 | A Study of NX-5948 in Adults With CLL/SLL Previously Treated With a Bruton's Tyrosine… | Chronic Lymphocytic Leukemia (CLL) | Recruiting |
| Phase 1/2 | |||
| NCT07520006 | Study of NX-5948 in Combination With Other Agents in Adults With B-cell Malignancies | B-cell Lymphoma | Not Yet Recruiting |
| Phase 1 | |||
| NCT05107674 | A Study of NX-1607 in Adults With Advanced Malignancies | Ovarian Cancer, Epithelial | Recruiting |
| NCT04830137 | A Study of NX-2127 in Adults With Relapsed/Refractory B-cell Malignancies | Chronic Lymphocytic Leukemia (CLL) | Recruiting |
| NCT05131022 | A Study of NX-5948 in Adults With Relapsed/Refractory B-cell Malignancies | Chronic Lymphocytic Leukemia (CLL) | Recruiting |