Sponsor pipeline

Institute of Cancer Research, United Kingdom clinical trial pipeline

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Data updated daily from ClinicalTrials.gov, last refresh 2026-10-16

Active trials by phase

Phase 1
5
Phase 1/2
6
Phase 2
6
Phase 3
4
Not charted: 20 active trials with no phase listed on ClinicalTrials.gov (typically behavioural, device, procedure and observational studies).

Active trials top 25 of 41

NCT IDTitleConditionStatusUpdated
Phase 3
NCT05613023 A Trial of 5 Fraction Prostate SBRT Versus 5 Fraction Prostate and Pelvic Nodal SBRT Prostate Cancer Recruiting 2024-09-19
NCT02305654 International Penile Advanced Cancer Trial (International Rare Cancers Initiative Study) Squamous Cell Carcinoma of the Penis, Usual Type Active, Not Recruiting 2026-08-31
NCT04584853 PreOperative Endocrine Therapy for Individualised Care With Abemaciclib Breast Cancer Female Active, Not Recruiting 2026-01-14
NCT02338310 Trial of Perioperative Endocrine Therapy - Individualising Care Breast Cancer Active, Not Recruiting 2020-02-17
Phase 2
NCT05990192 SBRT Alone or Followed by Niraparib for Oligometastases or Oligoprogression in Ovarian… Ovarian Cancer Recurrent Recruiting 2026-07-13
NCT03740893 PHOENIX DDR/Anti-PD-L1 Trial: A Pre-surgical Window of Opportunity and Post-surgical… Breast Neoplasm Recruiting 2025-08-11
NCT03946202 KORTUC Phase II - Intra-tumoural Radiation Sensitizer in Patients With Locally… Breast Cancer Active, Not Recruiting 2026-09-02
NCT04065269 ATr Inhibitor in Combination With Olaparib/Durvalumab (MEDI4736) in Gynaecological… Gynaecological Cancers Active, Not Recruiting 2026-02-20
NCT02955082 The BARCODE 2 Study - The Use of Genetic Profiling to Guide Prostate Cancer Treatment Hormone Refractory Prostate Cancer Active, Not Recruiting 2026-02-04
NCT02447549 Study of Tumour Focused Radiotherapy for Bladder Cancer Bladder Cancer Active, Not Recruiting 2020-06-09
Phase 1/2
NCT07002320 Investigating SX-682 in Combination With Apalutamide in Metastatic Castration-resistant… Metastatic Castrate-Resistant Prostate Cancer (mCRPC) Recruiting 2026-09-08
NCT07718243 Investigating the Combination of Bexmarilimab and Nivolumab in Solid Tumours, Melanoma… Melanoma (Skin Cancer) Recruiting 2026-09-08
NCT07391215 5G-PEARL: Paxalisib in Malignant Brain Tumours Malignant Primary Gliomas Recruiting 2026-02-05
NCT06630260 5G-RUBY: Avutometinib and Defactinib in Malignant Brain Tumours Glioblastoma Multiforme (GBM) Recruiting 2026-01-21
NCT06126731 Combination Study of Antibiotics With Enzalutamide (PROMIZE) Metastatic Castration-Resistant Prostate Cancer (mCRPC) Recruiting 2025-11-24
NCT03673787 A Trial of Ipatasertib in Combination With Atezolizumab Solid Tumor Active, Not Recruiting 2025-05-14
Phase 1
NCT06976892 Investigating Idetrexed and Olaparib in Patients With Ovarian Cancer High Grade Serous Ovarian Cancer Recruiting 2025-08-13
NCT06632236 5G-EMERALD: Amivantamab in Malignant Brain Tumours Malignant Primary Gliomas Active, Not Recruiting 2026-08-17
NCT05082259 ASTEROID: A Trial of ASTX660 in Combination With Pembrolizumab Advanced Cancer Active, Not Recruiting 2026-06-25
NCT05782361 POTENT - Tepotinib in Combination With Pembrolizumab in NSCLC Advanced Cancer Active, Not Recruiting 2026-04-24
NCT03875820 Phase I Trial of Defactinib and VS-6766. NSCLC Active, Not Recruiting 2026-03-10
Not applicable
NCT04595019 Hypofractionated Expedited Radiotherapy for Men With localisEd proState Cancer Prostate Cancer Recruiting 2022-06-13
Not specified
NCT07737509 Understanding the Genetic and Biological Factors That Influence Cancer Treatment Response… Advanced Solid Tumours Recruiting 2026-07-31
NCT05810467 The Active Surveillance Study Prostate Cancer Recruiting 2026-02-04
NCT06636526 The i4i PRODICT® Study: Evaluation of the i4i PRODICT® Test in Different Ethnic Groups… Prostate Cancer Recruiting 2026-02-04

Disease areas by active trials, top 10 of 18

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