| Detected | Trial | Change |
|---|---|---|
| 2026-08-15 | NCT07604766 An Extension Study to Assess the Efficacy of Rina-S Compared to Treatment of… |
Recruitment opened |
| 2026-08-15 | NCT07604766 An Extension Study to Assess the Efficacy of Rina-S Compared to Treatment of… |
Trial sites reduced: 20 -> 17 locations |
| 2026-08-05 | NCT03917381 GEN1046 Safety Trial in Patients With Malignant Solid Tumors |
Primary endpoint(s) modified |
| 2026-08-05 | NCT07288177 Study to Assess the Efficacy and Safety of Rina-S in Participants With Non-small Cell… |
Trial sites expanded: 41 -> 57 locations |
| 2026-08-05 | NCT06191744 Study of Subcutaneous Epcoritamab in Combination With Intravenous Rituximab and Oral… |
Enrollment closed, study ongoing |
| 2026-08-05 | NCT07166094 Study to Assess the Efficacy and Safety of Rina-S Compared to Treatment of Investigator's… |
Trial sites expanded: 120 -> 147 locations |
| 2026-07-21 | NCT07564141 Study to Assess the Efficacy and Safety of Rina-S With or Without Bevacizumab Compared to… |
Recruitment opened |
| 2026-07-21 | NCT07702032 Study of Petosemtamab Plus Chemotherapy Versus Cetuximab Plus Chemotherapy in RAS and… |
Recruitment opened |
| NCT ID | Title | Condition | Status |
|---|---|---|---|
| Phase 3 | |||
| NCT07166094 | Study to Assess the Efficacy and Safety of Rina-S Compared to Treatment of Investigator's… | Endometrial Cancer | Recruiting |
| NCT07225270 | Study to Assess the Efficacy and Safety of Rina-S Plus Standard of Care Compared to… | Ovarian Cancer | Recruiting |
| NCT07564141 | Study to Assess the Efficacy and Safety of Rina-S With or Without Bevacizumab Compared to… | Platinum-Sensitive Ovarian Cancer | Recruiting |
| NCT07604766 | An Extension Study to Assess the Efficacy of Rina-S Compared to Treatment of… | Platinum-resistant Ovarian Cancer | Recruiting |
| NCT07702032 | Study of Petosemtamab Plus Chemotherapy Versus Cetuximab Plus Chemotherapy in RAS and… | Left-sided Colorectal Cancer | Recruiting |
| NCT05578976 | A Study to Evaluate Change in Disease Activity of Subcutaneous (SC) Epcoritamab Combined… | Diffuse Large B-Cell Lymphoma | Active, Not Recruiting |
| NCT06508658 | A Study of Subcutaneously Injected Epcoritamab Plus Oral Lenalidomide Tablets Compared to… | Diffuse Large B-Cell Lymphoma | Active, Not Recruiting |
| NCT07226752 | A Sub-study Trial of Epcoritamab vs Investigator's Choice Chemotherapy in… | Diffuse Large B-Cell Lymphoma | Active, Not Recruiting |
| NCT04628494 | A Phase 3 Trial of Epcoritamab vs Investigator's Choice Chemotherapy in… | Diffuse Large B-cell Lymphoma | Active, Not Recruiting |
| NCT05409066 | Study of Subcutaneous Epcoritamab in Combination With Intravenous Rituximab and Oral… | Follicular Lymphoma (FL) | Active, Not Recruiting |
| NCT06191744 | Study of Subcutaneous Epcoritamab in Combination With Intravenous Rituximab and Oral… | Follicular Lymphoma (FL) | Active, Not Recruiting |
| NCT06635824 | Trial to Evaluate Acasunlimab and Pembrolizumab Combination Superiority Over Standard of… | PD-L1-positive, Locally Advanced (Unresectable Stage IIIB/C) or Metastatic NSCLC | Active, Not Recruiting |
| NCT06619236 | Study to Assess the Efficacy of Rina-S Compared to Treatment of Investigator's Choice in… | Platinum-resistant Ovarian Cancer | Active, Not Recruiting |
| Phase 2 | |||
| NCT07288177 | Study to Assess the Efficacy and Safety of Rina-S in Participants With Non-small Cell… | Non-small Cell Lung Cancer (NSCLC) | Recruiting |
| NCT07539311 | Study to Assess the Efficacy and Safety of Rina-S in Participants With Advanced… | Gastrointestinal Cancers | Recruiting |
| NCT05451810 | A Study to Evaluate Adverse Events of Subcutaneous (SC) Epcoritamab Administered in the… | Diffuse Large B-Cell Lymphoma | Active, Not Recruiting |
| NCT05117242 | Safety and Efficacy Study of GEN1046 as a Single Agent or in Combination With… | Non Small Cell Lung Cancer Metastatic | Active, Not Recruiting |
| NCT05283720 | A Study to Evaluate Adverse Events and Change in Disease Activity of Subcutaneous (SC)… | Non-Hodgkin Lymphoma | Active, Not Recruiting |
| Phase 1/2 | |||
| NCT05579366 | Rinatabart Sesutecan (Rina-S, PRO1184, GEN1184) for Advanced Solid Tumors (GCT1184-01/… | High Grade Epithelial Ovarian Cancer | Recruiting |
| NCT05201248 | A Study to Evaluate Adverse Events and Change in Disease Activity of Subcutaneous (SC)… | B-Cell Non-Hodgkin Lymphoma | Active, Not Recruiting |
| NCT03625037 | First-in-Human (FIH) Trial in Patients With Relapsed, Progressive or Refractory B-Cell… | DLBCL | Active, Not Recruiting |
| NCT03917381 | GEN1046 Safety Trial in Patients With Malignant Solid Tumors | Solid Tumors | Active, Not Recruiting |
| NCT04083599 | GEN1042 Safety Trial and Anti-tumor Activity in Participants With Malignant Solid Tumors | Malignant Solid Tumor | Active, Not Recruiting |
| NCT04542824 | Trial of the Safety and Efficacy of Epcoritamab in Japanese Subjects With Relapsed or… | Diffuse Large B Cell Lymphoma | Active, Not Recruiting |
| NCT04623541 | Safety and Efficacy Study of Epcoritamab in Subjects With Relapsed/Refractory Chronic… | Relapsed/Refractory Chronic Lymphocytic Leukemia | Active, Not Recruiting |