Sponsor pipeline

Essen Biotech clinical trial pipeline

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Data updated daily from ClinicalTrials.gov, last refresh 2026-10-16

Active trials by phase

Phase 1/2
17

Active trials

NCT IDTitleConditionStatusUpdated
Phase 1/2
NCT07410494 Biomarker-Guided Allogeneic Single-Target or Dual-Target CAR-NK Cell Therapy for Advanced… Cancer Recruiting 2026-02-18
NCT07410676 EBNK-001 Allogeneic NK Cells With Low-Dose IL-15 ± Pembrolizumab in Advanced Solid Tumors Cancer Recruiting 2026-02-18
NCT06213636 Fourth-gen CAR T Cells Targeting CD19/CD22 for Highly Resistant B-cell Lymphoma/Leukemia… Acute Lymphoblastic Leukemia, Adult B-Cell Recruiting 2025-08-06
NCT07067255 Sequential CD146 and GPC3 CAR-T Cell Therapy in Advanced Ovarian Cancer Ovarian Cancer Recruiting 2025-07-16
NCT07066982 Sequential Infusion of CD146-Targeted and HER2-Targeted CAR T Cells in Patients With… Sarcoma Recruiting 2025-07-15
NCT07066995 Mesothelin and Claudin 18.2 Dual-Target CAR-T Therapy in Advanced Pancreatic Cancer Pancreatic Cancer Recruiting 2025-07-15
NCT07032129 Sequential CAR-T Cells Targeting BCMA/GPRC5D in Patients With Relapsed/ Refractory… Multiple Myeloma Recruiting 2025-06-22
NCT06420063 Sequential CAR-T Cells Targeting CD33/CD123 in Patients With Acute Myelocytic Leukemia AML AML Recruiting 2024-11-12
NCT06420076 Sequential CAR-T Cells Therapy for CD5/CD7 Positive T-cell Acute Lymphoblastic Leukemia… T Cell Lymphoma Recruiting 2024-11-12
NCT06532799 TIL Therapy Combined With Pembrolizumab for Advanced or Metastatic Refractory Stomach and… Stomach Cancer Recruiting 2024-11-12
NCT06532812 TIL Gean Therapy Combined With Immunotherapy for Advanced or Metastatic Refractory Breast… Breast Cancer Recruiting 2024-11-12
NCT06399107 Investigation Into the Use of BAH243 Lentiviral Vector for Gene Therapy in Treating… Sickle Cell Disease Recruiting 2024-11-05
NCT06428188 Sequential CAR-T Cells Targeting BCMA/CD19 in Patients With Relapsed/ Refractory… Autoimmune Diseases Recruiting 2024-11-05
NCT06530303 Biological Tumor Infiltrating Lymphocytes Therapy With Immunotherapy for Colon and Rectum… Colorectal Cancer Recruiting 2024-11-05
NCT06640582 TIL Therapy Combined With Pembrolizumab for Advanced Brain Cancer Including Gliomas and… Brain Tumor Recruiting 2024-11-05
NCT06350110 Fourth-gen CAR T Cells Targeting BCMA/CD19 for Refractory Systemic Lupus Erythematosus… Systemic Lupus Erythematosus Recruiting 2024-10-15
NCT06538012 TIL Therapy Combined With Pembrolizumab for Advanced or Metastatic Refractory Lung Cancer Lung Cancer Recruiting 2024-10-15

Disease areas by active trials, top 10 of 28

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