| Detected | Trial | Change |
|---|---|---|
| 2026-07-30 | NCT06419621 PM8002 or Placebo Plus Nab-Paclitaxel as First-line Treatment in Inoperable Locally… |
Enrollment closed, study ongoing |
| 2026-07-24 | NCT07133750 PM8002 (BNT327) in Combination With Chemotherapy in Patients With Metastatic Colorectal… |
Recruitment opened |
| 2026-07-24 | NCT07133750 PM8002 (BNT327) in Combination With Chemotherapy in Patients With Metastatic Colorectal… |
Enrollment increased: 40 -> 100 participants |
| 2026-07-24 | NCT07133750 PM8002 (BNT327) in Combination With Chemotherapy in Patients With Metastatic Colorectal… |
Trial arms changed: 4 -> 6 |
| 2026-07-24 | NCT07133750 PM8002 (BNT327) in Combination With Chemotherapy in Patients With Metastatic Colorectal… |
Trial sites expanded: 1 -> 11 locations |
| 2026-07-24 | NCT07133750 PM8002 (BNT327) in Combination With Chemotherapy in Patients With Metastatic Colorectal… |
date change Primary completion pushed: 2026-08 -> 2027-05 |
| 2026-07-24 | NCT07133750 PM8002 (BNT327) in Combination With Chemotherapy in Patients With Metastatic Colorectal… |
date change Completion pushed: 2029-08 -> 2030-05 |
| NCT ID | Title | Condition | Status |
|---|---|---|---|
| Phase 3 | |||
| NCT06616532 | PM8002 in Combination With Paclitaxel Compared With Chemotherapy as Second-line Treatment… | SCLC | Active, Not Recruiting |
| NCT06419621 | PM8002 or Placebo Plus Nab-Paclitaxel as First-line Treatment in Inoperable Locally… | Triple Negative Breast Cancer(TNBC) | Active, Not Recruiting |
| Phase 2 | |||
| NCT07133750 | PM8002 (BNT327) in Combination With Chemotherapy in Patients With Metastatic Colorectal… | CRC (Colorectal Cancer) | Recruiting |
| NCT05879068 | A Study of PM8002 in Combination With Chemotherapy in Patients With SCLC | SCLC | Active, Not Recruiting |
| NCT05844150 | A Study of PM8002 (Anti-PD-L1/VEGF) in Combination With Chemotherapy in Patients With… | SCLC | Active, Not Recruiting |
| NCT05756972 | A Study of PM8002 (Anti-PD-L1/VEGF) in Combination With Chemotherapy in Patients With… | NSCLC | Active, Not Recruiting |
| NCT05879055 | A Study of PM8002 in Combination With Chemotherapy in Patients With NEN | Neuroendocrine Neoplasm | Active, Not Recruiting |
| Phase 1/2 | |||
| NCT05918445 | PM8002 in the Treatment of Patients With Advanced Solid Tumors | Malignant Neoplasm | Recruiting |
| NCT06584071 | A Study to Evaluate of PM8002 Combined With PM1009 in Patients With First-line HCC | HCC | Not Yet Recruiting |
| NCT05918133 | A Study of PM8002 Plus Nab-paclitaxel as First Line Therapy for TNBC | TNBC | Active, Not Recruiting |