Drug Pipeline

Tiragolumab Clinical Trials

Data updated daily from ClinicalTrials.gov — last refresh 2026-06-12
18
Active Studies
5
Recruiting
4
Phase 3
5
Top Sponsors
2
Changes, 30 Days
What Changed in the Last 30 Days
DetectedTrialChange
2026-06-03 NCT05681039
Phase 2 Trial of Neoadjuvant and Adjuvant Tiragolumab Plus Atezolizumab in Patients With…
overall status: "Recruiting" → "Active Not Recruiting"
2026-05-27 NCT04929223
A Study Evaluating the Safety and Efficacy of Targeted Therapies in Subpopulations of…
Trial sites expanded: 76 -> 82 locations
Active Studies by Phase
Phase 3
4
Phase 2
8
Phase 1/2
4
Phase 1
2
Active Trials
NCT IDTitleConditionStatus
Phase 3
NCT05862285 A Rollover Study for Participants Previously Enrolled in a Genentech and/or F. Hoffman-La… Cancer Recruiting
NCT05904886 A Study Evaluating Atezolizumab and Bevacizumab, With or Without Tiragolumab, in… Hepatocellular Carcinoma Active, Not Recruiting
NCT04665856 Study of Atezolizumab Plus Carboplatin and Etoposide With or Without Tiragolumab in… Small Cell Lung Carcinoma Active, Not Recruiting
NCT04543617 A Study of Atezolizumab With or Without Tiragolumab in Participants With Unresectable… Esophageal Squamous Cell Carcinoma Active, Not Recruiting
Phase 2
NCT04958811 Tiragolumab With Atezolizumab Plus Bevacizumab in Previously-Treated Advanced… Non-squamous Non-small-cell Lung Cancer Active, Not Recruiting
NCT06754501 A Phase 2 Clinical Trial Evaluating the Efficacy and Safety of Dual Immune Checkpoint… Cancer Active, Not Recruiting
NCT05009069 A Study of Atezolizumab With or Without Tiragolumab Following Neoadjuvant… Rectal Neoplasms Active, Not Recruiting
NCT05645692 A Study Evaluating Different Immunotherapies (LAG-3 and PD-1 With or Without TIGIT… Urothelial Cancer Active, Not Recruiting
NCT03784326 Phase I/II Study of Perioperative Chemotherapy Plus Immunotherapy Followed by Surgery in… Clinical Stage II Esophageal Adenocarcinoma AJCC v8 Active, Not Recruiting
NCT05805501 A Study of Immune Checkpoint Inhibitor Combinations With Axitinib in Participants With… Renal Cell Carcinoma Active, Not Recruiting
NCT05681039 Phase 2 Trial of Neoadjuvant and Adjuvant Tiragolumab Plus Atezolizumab in Patients With… Squamous Cell Carcinoma Active, Not Recruiting
NCT05798663 Atezolizumab Immunotherapy With or Without Tiragolumab for Patients With Unresectable… NSCLC Active, Not Recruiting
Phase 1/2
NCT04486352 A Study of Targeted Agents for Patients With Recurrent or Persistent Endometrial Cancer Endometrial Cancer Recruiting
NCT05394337 Neoadjuvant PD-1 Plus TIGIT Blockade in Patients With Cisplatin-Ineligible Operable… Metastatic Malignancy Recruiting
NCT04524871 A Study Evaluating the Efficacy and Safety of Multiple Immunotherapy-Based Treatment… Advanced Liver Cancers Recruiting
NCT05286801 Tiragolumab and Atezolizumab for the Treatment of Relapsed or Refractory SMARCB1 or… Atypical Teratoid/Rhabdoid Tumor Active, Not Recruiting
Phase 1
NCT04929223 A Study Evaluating the Safety and Efficacy of Targeted Therapies in Subpopulations of… Metastatic Colorectal Cancer Recruiting
NCT06760481 Phase I/Ib Trial of TIraGolumab, AtEzolizumab, and RadScopal Radiation in Patients With… Advanced Solid Malignancies Active, Not Recruiting
Sponsors Running Tiragolumab Trials
Disease Areas
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