| Detected | Trial | Change |
|---|---|---|
| 2026-06-11 | NCT07462663 SHAPE-ENDO: Pilot Randomized Trial of Multimodal Pre-Surgical Optimization Versus… |
Primary endpoint(s) modified |
| 2026-06-11 | NCT07462663 SHAPE-ENDO: Pilot Randomized Trial of Multimodal Pre-Surgical Optimization Versus… |
Trial arms changed: 1 -> 2 |
| 2026-06-11 | NCT07462663 SHAPE-ENDO: Pilot Randomized Trial of Multimodal Pre-Surgical Optimization Versus… |
date change Primary completion pushed: 2027-05 -> 2031-04 |
| 2026-06-11 | NCT07462663 SHAPE-ENDO: Pilot Randomized Trial of Multimodal Pre-Surgical Optimization Versus… |
date change Completion pushed: 2028-09 -> 2035-01 |
| 2026-06-04 | NCT03671811 Megestrol Acetate With or Without Pterostilbene in Treating Patients With Endometrial… |
date change Completion pushed: 2026-03-30 -> 2027-02-28 |
| 2026-05-28 | NCT06904274 Mirena for the Treatment of Nonatypical Endometrial Hyperplasia for 6 Months |
date change Primary completion pushed: 2027-08-02 -> 2027-10-01 |
| 2026-05-28 | NCT06904274 Mirena for the Treatment of Nonatypical Endometrial Hyperplasia for 6 Months |
date change Completion pushed: 2027-08-02 -> 2027-10-01 |
| 2026-05-16 | NCT04423211 Treating Prostate Cancer That Has Come Back After Surgery With Apalutamide and Targeted… |
Trial sites expanded: 303 -> 342 locations |
| 2026-05-14 | NCT07462663 SHAPE-ENDO: Pilot Randomized Trial of Multimodal Pre-Surgical Optimization Versus… |
Phase changed: [] -> ['PHASE4'] |
| 2026-05-14 | NCT07455903 Assessing Efficacy of Neoadjuvant ADT in Localized High-Risk Prostate Cancer Patients… |
Recruitment opened |
| NCT ID | Title | Condition | Status |
|---|---|---|---|
| Phase 4 | |||
| NCT07462663 | SHAPE-ENDO: Pilot Randomized Trial of Multimodal Pre-Surgical Optimization Versus… | Endometrial Cancer | Not Yet Recruiting |
| Phase 3 | |||
| NCT06671548 | Efficacy & Safety Study of Relugolix in Women With Heavy Menstrual Bleeding Associated… | Heavy Menstrual Bleeding | Recruiting |
| NCT06650579 | REVELUTION-2: Relugolix+Abiraterone Acetate (AA) Versus Leuprolide+AA Cardiac Trial | Recurrent Prostate Carcinoma | Recruiting |
| NCT04423211 | Treating Prostate Cancer That Has Come Back After Surgery With Apalutamide and Targeted… | Biochemically Recurrent Prostate Carcinoma | Recruiting |
| NCT06904274 | Mirena for the Treatment of Nonatypical Endometrial Hyperplasia for 6 Months | Endometrial Hyperplasia | Recruiting |
| NCT04939090 | Olanzapine Versus Megestrol Acetate for the Treatment of Loss of Appetite Among Advanced… | Advanced Malignant Solid Neoplasm | Active, Not Recruiting |
| NCT04513717 | Two Studies for Patients With High Risk Prostate Cancer Testing Less Intense Treatment… | Prostate Adenocarcinoma | Active, Not Recruiting |
| NCT05050084 | Two Studies for Patients With Unfavorable Intermediate Risk Prostate Cancer Testing Less… | Prostate Adenocarcinoma | Active, Not Recruiting |
| Phase 2/3 | |||
| NCT07319429 | Refining Fertility-sparing Treatment in Endometrial Carcinoma Based on Molecular… | Endometrial Cancer | Recruiting |
| NCT05255653 | Refining Adjuvant Treatment IN Endometrial Cancer Based On Molecular Features | Endometrial Cancer | Recruiting |
| NCT05316493 | Weight Management Plus LNG-IUS/Megestrol Acetate in Endometrial Atypical Hyperplasia | Atypical Endometrial Hyperplasia | Recruiting |
| Phase 2 | |||
| NCT06059118 | Difluoromethylornithine and High Dose Testosterone With Enzalutamide in Metastatic… | Prostate Cancer | Recruiting |
| NCT06330805 | Effects of Relugolix vs Leuprolide on Cardiac Function in Patients With Prostate Cancer | Prostate Adenocarcinoma | Recruiting |
| NCT07142551 | Supraphysiologic Testosterone Priming Induces Darolutamide Extended Response | Metastatic Castration-resistant Prostate Cancer | Recruiting |
| NCT07025369 | Androgen Deprivation Therapy (Relugolix) for the Improvement of Diagnostic Imaging (PSMA… | Prostate Adenocarcinoma | Recruiting |
| NCT06378866 | Stereotactic Body Radiation Therapy Plus Immediate or Delayed Androgen Receptor Pathway… | Recurrent Castration-Sensitive Prostate Carcinoma | Recruiting |
| NCT06111781 | The SUGAR Study; SBRT and Relugolix) for Prostate Cancer | Prostate Cancer | Recruiting |
| NCT07455903 | Assessing Efficacy of Neoadjuvant ADT in Localized High-Risk Prostate Cancer Patients… | Prostate Cancer | Recruiting |
| NCT05247268 | Gonadotropin-releasing Hormone Agonist (GnRHa) Plus Letrozole In Young Women With Early… | Endometrial Neoplasm Malignant Stage I | Recruiting |
| NCT06499870 | Relugolix and Enzalutamide in Combination With Radiation Therapy for the Treatment of… | Prostate Adenocarcinoma | Recruiting |
| NCT04576104 | Megestrol Acetate Compared With Megestrol Acetate and Metformin to Prevent Endometrial… | Endometrial Atypical Hyperplasia/Endometrioid Intraepithelial Neoplasia | Active, Not Recruiting |
| NCT05320406 | RElugolix VErsus LeUprolide Cardiac Trial | Biochemically Recurrent Prostate Carcinoma | Active, Not Recruiting |
| NCT07436793 | Progestins for the Treatment of Endometrial Cancer or Precancers of the Uterus Before… | Endometrial Endometrioid Adenocarcinoma | Not Yet Recruiting |
| NCT06463457 | Comeback From Long coursE Androgen Deprivation Therapy (ADT) With RElugolix and… | Prostate Cancer | Active, Not Recruiting |
| NCT06734130 | Adaptive Androgen Deprivation and Docetaxel in Metastatic Castration Sensitive Prostate… | Metastatic Castration Sensitive Prostate Cancer | Active, Not Recruiting |