Clinical Trial

Gonadotropin-releasing Hormone Agonist (GnRHa) Plus Letrozole In Young Women With Early Endometrial Cancer

Name: Gonadotropin-releasing Hormone Agonist (GnRHa) Plus Letrozole In Young Women With Early Endometrial Cancer — clinical trial record (NCT05247268)
Creator: DataLookout
License: https://creativecommons.org/licenses/by/4.0/

Recruiting Phase 2

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Summary

To see if Gonadotropin-releasing hormone analogue (GnRHa) combined with aromatase inhibitors (AIs) will achieve better complete response rate than megestrol acetate or medroxyprogesterone acetate (MA/MPA) alone as fertility-sparing treatment for patients with early endometrial carcinoma.

Trial Details

NCT Number	NCT05247268
Lead Sponsor	Fudan University Collaborators: Peking Union Medical College Hospital
Conditions	Endometrial Neoplasm Malignant Stage I
Enrollment	104 participants
Start Date	2022-03-11
Primary Completion	2027-03-10 (estimated)
Study Completion	2027-09-10 (estimated)
Updated on ClinicalTrials.gov	2026-06-04