| Detected | Trial | Change |
|---|---|---|
| 2026-06-09 | NCT04619004 HERTHENA-Lung01: Patritumab Deruxtecan in Subjects With Metastatic or Locally Advanced… |
date change Completion pushed: 2026-07-03 -> 2027-01-06 |
| 2026-05-27 | NCT07286149 A Clinical Study of MK-1084 With Other Treatments for Non-small Cell Lung Cancer… |
Trial sites expanded: 12 -> 18 locations |
| 2026-05-15 | NCT07286149 A Clinical Study of MK-1084 With Other Treatments for Non-small Cell Lung Cancer… |
Trial sites expanded: 4 -> 12 locations |
| NCT ID | Title | Condition | Status |
|---|---|---|---|
| Phase 3 | |||
| NCT07060807 | A Clinical Study of Patritumab Deruxtecan to Treat Breast Cancer (MK-1022-016) | Breast Neoplasms | Recruiting |
| Phase 2 | |||
| NCT06172478 | A Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors | Advanced Solid Tumor | Recruiting |
| NCT06797635 | Study of Patritumab Deruxtecan Plus Pembrolizumab With Other Anticancer Agents in… | Breast Neoplasms | Recruiting |
| NCT06731907 | A Study of Pembrolizumab With or Without Chemotherapy in Combination With Additional… | Non-small Cell Lung Cancer | Recruiting |
| NCT04619004 | HERTHENA-Lung01: Patritumab Deruxtecan in Subjects With Metastatic or Locally Advanced… | Non-Small Cell Lung Cancer Metastatic | Active, Not Recruiting |
| Phase 1/2 | |||
| NCT06445972 | Substudy 06D: Combination Therapies in Second Line (2L) Gastroesophageal Adenocarcinoma… | Gastroesophageal Junction | Recruiting |
| NCT06941272 | A Study of Patritumab Deruxtecan in Pediatric Participants With Relapsed or Refractory… | Malignant Neoplasm | Recruiting |
| NCT04165070 | KEYMAKER-U01 Substudy 01A: Efficacy and Safety Study of Pembrolizumab (MK-3475) With or… | Carcinoma, Non-Small-Cell Lung | Recruiting |
| NCT06686394 | Study of Patritumab Deruxtecan With Other Anticancer Agents in Participants With HER2… | Breast Neoplasms | Recruiting |
| NCT06469944 | Substudy 06C: A Study of Investigational Agents With Pembrolizumab (MK-3475) and… | Gastroesophageal Junction | Recruiting |
| NCT07286149 | A Clinical Study of MK-1084 With Other Treatments for Non-small Cell Lung Cancer… | Lung Neoplasm Malignant | Recruiting |
| NCT06596694 | Study of Patritumab Deruxtecan in Participants With Gastrointestinal Cancers… | Gastrointestinal Cancer | Recruiting |
| Phase 1 | |||
| NCT03260491 | U3-1402 in Metastatic or Unresectable Non-Small Cell Lung Cancer | Non-Small Cell Lung Cancer (NSCLC) | Active, Not Recruiting |