| Detected | Trial | Change |
|---|---|---|
| 2026-06-12 | NCT05765851 A Study of DS-1103a Combination Therapy in Participants With Advanced Solid Tumors |
overall status: "Active Not Recruiting" → "Recruiting" |
| 2026-06-09 | NCT04619004 HERTHENA-Lung01: Patritumab Deruxtecan in Subjects With Metastatic or Locally Advanced… |
date change Completion pushed: 2026-07-03 -> 2027-01-06 |
| 2026-05-29 | NCT07022483 Study of Trastuzumab Deruxtecan Versus Standard of Care Chemotherapy for HER2-Expressing… |
Trial sites expanded: 40 -> 61 locations |
| 2026-05-29 | NCT04145622 Study of Ifinatamab Deruxtecan (DS-7300a, I-DXd) in Participants With Advanced Solid… |
Trial sites expanded: 25 -> 28 locations |
| 2026-05-27 | NCT06819007 Study of Trastuzumab Deruxtecan With Bevacizumab Versus Bevacizumab Monotherapy for… |
Trial sites expanded: 180 -> 193 locations |
| 2026-05-23 | NCT06161025 A Study of Raludotatug Deruxtecan (R-DXd) in Subjects With Platinum-resistant, High-grade… |
Trial sites expanded: 129 -> 146 locations |
| 2026-05-16 | NCT07244341 A Study of Valemetostat (DS-3201b) in Combination With Darolutamide in Metastatic… |
Trial sites expanded: 6 -> 19 locations |
| 2026-05-15 | NCT07129993 Study of Datopotamab Deruxtecan Plus Carboplatin or Cisplatin Versus Gemcitabine Plus… |
Trial sites expanded: 80 -> 98 locations |
| NCT ID | Title | Condition | Status |
|---|---|---|---|
| Phase 3 | |||
| NCT06899126 | Study of Trastuzumab Deruxtecan, Pembrolizumab, and Platinum-based Chemotherapy in… | Non-small Cell Lung Cancer | Recruiting |
| NCT06644781 | A Study of Ifinatamab Deruxtecan in Subjects With Pretreated Advanced or Metastatic… | Esophageal Squamous Cell Carcinoma | Recruiting |
| NCT06731478 | Study of TDXd, Chemotherapy, Pembrolizumab, and Trastuzumab in First-Line Metastatic… | Gastric Cancer | Recruiting |
| NCT05950945 | Trastuzumab Deruxtecan (T-DXd) in Patients Who Have Hormone Receptor-negative and Hormone… | Breast Cancer | Recruiting |
| NCT06578247 | Quizartinib or Placebo Plus Chemotherapy in Newly Diagnosed Patients With FLT3-ITD… | Leukemia | Recruiting |
| NCT05215340 | Study of Dato-DXd Plus Pembrolizumab vs Pembrolizumab Alone in the First-line Treatment… | Metastatic Non Small Cell Lung Cancer | Recruiting |
| NCT06819007 | Study of Trastuzumab Deruxtecan With Bevacizumab Versus Bevacizumab Monotherapy for… | Ovarian Cancer | Recruiting |
| NCT07022483 | Study of Trastuzumab Deruxtecan Versus Standard of Care Chemotherapy for HER2-Expressing… | Endometrial Cancer | Recruiting |
| NCT06203210 | A Study of Ifinatamab Deruxtecan Versus Treatment of Physician's Choice in Subjects With… | Small Cell Lung Cancer | Recruiting |
| NCT07474649 | A Study of Bempedoic Acid/Ezetimibe/High-intensity Statin in Patients Without… | Coronary Atherosclerosis | Not Yet Recruiting |
| NCT04656652 | Study of DS-1062a Versus Docetaxel in Previously Treated Advanced or Metastatic Non-small… | Non-small Cell Lung Cancer | Active, Not Recruiting |
| NCT05555732 | Datopotamab Deruxtecan (Dato-DXd) and Pembrolizumab With or Without Platinum Chemotherapy… | Metastatic Non Small Cell Lung Cancer | Active, Not Recruiting |
| NCT04622319 | A Study of Trastuzumab Deruxtecan (T-DXd) Versus Trastuzumab Emtansine (T-DM1) in… | HER2-Positive Primary Breast Cancer | Active, Not Recruiting |
| NCT04704934 | Trastuzumab Deruxtecan for Subjects With HER2-Positive Gastric Cancer or… | Gastric Cancer, Adenocarcinoma | Active, Not Recruiting |
| Phase 2/3 | |||
| NCT06161025 | A Study of Raludotatug Deruxtecan (R-DXd) in Subjects With Platinum-resistant, High-grade… | Solid Cancer | Recruiting |
| NCT07129993 | Study of Datopotamab Deruxtecan Plus Carboplatin or Cisplatin Versus Gemcitabine Plus… | Urothelial Cancer | Recruiting |
| Phase 2 | |||
| NCT06330064 | A Study To Evaluate The Efficacy And Safety Of Ifinatamab Deruxtecan (I-DXd) In Subjects… | Recurrent or Metastatic Solid Tumors | Recruiting |
| NCT06172478 | A Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors | Advanced Solid Tumor | Recruiting |
| NCT05280470 | Ifinatamab Deruxtecan (I-DXd) in Subjects With Pretreated Extensive-Stage Small Cell Lung… | Extensive-stage Small-cell Lung Cancer | Active, Not Recruiting |
| NCT06660654 | A Study of Raludotatug Deruxtecan in Participants With Advanced/Metastatic Solid Tumors… | Advanced Solid Tumor | Active, Not Recruiting |
| NCT04619004 | HERTHENA-Lung01: Patritumab Deruxtecan in Subjects With Metastatic or Locally Advanced… | Non-Small Cell Lung Cancer Metastatic | Active, Not Recruiting |
| Phase 1/2 | |||
| NCT06362252 | A Study of I-DXd in Combination With Atezolizumab With or Without Carboplatin as… | Extensive Stage-small Cell Lung Cancer | Recruiting |
| NCT05875168 | First-in-Human Study of DS-3939a in Participants With Advanced Solid Tumors | Advanced Solid Tumor | Recruiting |
| NCT07220616 | A First-in-Human Trial of DS3790a in Participants With Hematological Malignancies | Hematological Malignancies | Recruiting |
| NCT04145622 | Study of Ifinatamab Deruxtecan (DS-7300a, I-DXd) in Participants With Advanced Solid… | Advanced Solid Tumor | Recruiting |