Drug Pipeline

Obinutuzumab Clinical Trials

Data updated daily from ClinicalTrials.gov — last refresh 2026-06-12
112
Active Studies
60
Recruiting
23
Phase 3
10
Top Sponsors
9
Changes, 30 Days
What Changed in the Last 30 Days
DetectedTrialChange
2026-06-11 NCT05100862
A Study of Zanubrutinib Plus Anti-CD20 Versus Lenalidomide Plus Rituximab in Participants…
Sponsor changed: BeiGene -> BeOne Medicines
2026-06-06 NCT07299019
A Study of Orelabrutinib in Patients With Secondary Progressive Multiple Sclerosis
Trial sites expanded: 9 -> 12 locations
2026-06-02 NCT04739813
Venetoclax, Ibrutinib, Prednisone, Obinutuzumab, and Revlimid in Combination With…
overall status: "Recruiting" → "Active Not Recruiting"
2026-06-02 NCT04739813
Venetoclax, Ibrutinib, Prednisone, Obinutuzumab, and Revlimid in Combination With…
Enrollment reduced: 55 -> 34 participants
2026-06-02 NCT04739813
Venetoclax, Ibrutinib, Prednisone, Obinutuzumab, and Revlimid in Combination With…
date change Primary completion moved earlier: 2026-06-18 -> 2026-05-07
2026-05-30 NCT04077723
A Study to Evaluate the Safety, Pharmacokinetics and Preliminary Anti-Tumor Activity of…
Trial sites reduced: 44 -> 35 locations
2026-05-27 NCT04889716
CAR-T Followed by Bispecific Antibodies
Primary endpoint(s) modified
2026-05-27 NCT04889716
CAR-T Followed by Bispecific Antibodies
Enrollment reduced: 42 -> 23 participants
2026-05-20 NCT07299019
A Study of Orelabrutinib in Patients With Secondary Progressive Multiple Sclerosis
Trial sites expanded: 5 -> 8 locations
New Trial Filings, Last 30 Days
First PostedTrialPhaseStatus
2026-06-08 NCT07634289 Radiotherapy in Combination With Glofitamab in Relapsed/Refractory Diffuse Large B Cell… Phase 2 Not Yet Recruiting
2026-06-03 NCT07624799 Fixed Duration Treatment With Combined Pirtobrutinib and Short Course Immuno-chemotherapy… Phase 2 Not Yet Recruiting
2026-05-29 NCT07613788 Rimegepant Plus Glofitamab and CD19 CAR-T Therapy in R/R LBCL Phase 2 Not Yet Recruiting
2026-05-20 NCT07599423 A Study of Glofitamab Plus GemOx Compared With Standard of Care in Patients With… Phase 2 Not Yet Recruiting
2026-05-15 NCT07591467 Carboplatin-Enhanced Therapy in BRCA-Mutated or Neuroendocrine-Differentiated Aggressive… Phase 3 Not Yet Recruiting
2026-05-14 NCT07585747 A Exploratory Study on Untreated Follicular Lymphoma With Orelabrutinib, Tafasitamab, and… Phase 2 Not Yet Recruiting
Active Studies by Phase
Phase 4
1
Phase 3
23
Phase 2
64
Phase 1/2
13
Phase 1
11
Active Trials — top 25 of 112
NCT IDTitleConditionStatus
Phase 4
NCT07355699 Application of Orelabrutinib With or Without CD20 Monoclonal Antibody in Previously… Marginal Zone Lymphoma(MZL) Recruiting
Phase 3
NCT06781944 OBINOTUZUMAB Versus Cyclophosphamide + Glucocorticoids in Primary Membranous… Primary Membranous Nephropathy Recruiting
NCT07377578 A Study of Rocbrutinib Versus Investigator's Choice of BTK Inhibitors in Patients With… Mantle Cell Lymphoma Recruiting
NCT06428019 A Study to Evaluate the Risk of Tumor Lysis Syndrome (TLS) in Adult Participants… Chronic Lymphocytic Leukemia Recruiting
NCT05045664 Early Stage Follicular LymphOma and RadioTherapy PLUS Anti-CD20 Antibody Early Stage Follicular Lymphoma WHO Grade 1/2 or 3a Recruiting
NCT07067463 A Study of Orelabrutinib in Patients With Primary Progressive Multiple Sclerosis Multiple Sclerosis (MS) Primary Progressive Recruiting
NCT06191744 Study of Subcutaneous Epcoritamab in Combination With Intravenous Rituximab and Oral… Follicular Lymphoma (FL) Recruiting
NCT06084936 A Study to Evaluate Glofitamab as a Single Agent vs. Investigator's Choice in… Lymphoma Recruiting
NCT06943872 A Study to Investigate Progression-Free Survival With Sonrotoclax Plus Obinutuzumab Or… Chronic Lymphocytic Leukemia Recruiting
NCT06284122 Study of Mosunetuzumab Plus Lenalidomide Compared to Anti-CD20 Anti-body + Chemotherapy… Follicular Lymphoma Recruiting
NCT07299019 A Study of Orelabrutinib in Patients With Secondary Progressive Multiple Sclerosis Secondary Progressive Multiple Sclerosis Recruiting
NCT05100862 A Study of Zanubrutinib Plus Anti-CD20 Versus Lenalidomide Plus Rituximab in Participants… Relapsed/Refractory Follicular Lymphoma Recruiting
NCT04269902 Testing Early Treatment for Patients With High-Risk Chronic Lymphocytic Leukemia (CLL) or… Chronic Lymphocytic Leukemia Recruiting
NCT04408638 A Phase III Study Evaluating Glofitamab in Combination With Gemcitabine + Oxaliplatin vs… Diffuse Large B-cell Lymphoma Active, Not Recruiting
NCT04629248 A Study Evaluating the Efficacy and Safety of Obinutuzumab in Participants With Primary… Primary Membranous Nephropathy Active, Not Recruiting
NCT04608318 Ibrutinib Monotherapy Versus Fixed-duration Venetoclax Plus Obinutuzumab Versus… Chronic Lymphoid Leukemia Active, Not Recruiting
NCT04221477 A Study to Evaluate the Efficacy and Safety of Obinutuzumab in Participants With ISN/RPS… Lupus Nephritis Active, Not Recruiting
NCT04963296 A Study to Evaluate the Efficacy and Safety of Obinutuzumab in Participants With Systemic… Systemic Lupus Erythematosus Active, Not Recruiting
NCT07591467 Carboplatin-Enhanced Therapy in BRCA-Mutated or Neuroendocrine-Differentiated Aggressive… BRCA-Mutated Not Yet Recruiting
NCT05057494 A Study of Acalabrutinib Plus Venetoclax Versus Venetoclax Plus Obinutuzumab in… Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma Active, Not Recruiting
NCT03701282 Assessing the Ability of Combination Treatment With Venetoclax to Permit Time Limited… Chronic Lymphocytic Leukemia Active, Not Recruiting
NCT03737981 Testing the Addition of a New Anti-cancer Drug, Venetoclax, to the Usual Treatment… Chronic Lymphocytic Leukemia Active, Not Recruiting
NCT06073821 Study of Sonrotoclax (BGB-11417) Plus Zanubrutinib (BGB-3111) Compared With Venetoclax… CLL Active, Not Recruiting
NCT03462719 A Study of the Combination of Ibrutinib Plus Venetoclax Versus Chlorambucil Plus… Leukemia, Lymphocytic, Chronic, B-Cell Active, Not Recruiting
Phase 2
NCT04505254 Acalabrutinib and Obinutuzumab for the Treatment of Chronic Lymphocytic Leukemia Chronic Lymphocytic Leukemia Recruiting
Sponsors Running Obinutuzumab Trials
Disease Areas
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