Drug Pipeline

Mesna Clinical Trials

Data updated daily from ClinicalTrials.gov — last refresh 2026-06-12
31
Active Studies
16
Recruiting
1
Phase 3
10
Top Sponsors
1
Changes, 30 Days
What Changed in the Last 30 Days
DetectedTrialChange
2026-05-19 NCT07428993
Evaluating Efficacy of B7-H3-CAR T Cells Administered at the End of Upfront Map…
Recruitment opened
Active Studies by Phase
Phase 3
1
Phase 2
13
Phase 1/2
5
Phase 1
10
Early Phase 1
1
Not specified
1
Active Trials — top 25 of 31
NCT IDTitleConditionStatus
Phase 3
NCT04530565 Testing the Use of Steroids and Tyrosine Kinase Inhibitors With Blinatumomab or… B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1 Active, Not Recruiting
Phase 2
NCT06345495 High Dose Ruxolitinib and Allogeneic Stem Cell Transplantation in Myelofibrosis Patients… Splenomegaly Recruiting
NCT06847269 CAR T CELL Therapy for Pediatric, Adolescent and Young Adult Patients With CD19-Positive… Acute Lymphoblastic Leukemia Recruiting
NCT04684368 A Study of a New Way to Treat Children and Young Adults With a Brain Tumor Called NGGCT Central Nervous System Nongerminomatous Germ Cell Tumor Recruiting
NCT07428993 Evaluating Efficacy of B7-H3-CAR T Cells Administered at the End of Upfront Map… Pediatric Osteosarcoma Recruiting
NCT06001385 HLA-Mismatched Unrelated Donor Peripheral Blood Stem Cell Transplantation With Reduced… Acute Lymphoblastic Leukemia Active, Not Recruiting
NCT03663933 Allogeneic Hematopoietic Cell Transplantation for Disorders of T-cell Proliferation… Lymphoproliferative Disorders Active, Not Recruiting
NCT04904588 HLA-Mismatched Unrelated Donor Hematopoietic Cell Transplantation With… Acute Lymphoblastic Leukemia Active, Not Recruiting
NCT00338377 Lymphodepletion Plus Adoptive Cell Transfer With or Without Dendritic Cell Immunization… Melanoma Active, Not Recruiting
NCT02106988 Concurrent Chemotherapy and Radiation Therapy for Newly Diagnosed Nasal NK Cell Lymphoma Lymphoma Active, Not Recruiting
NCT01864109 Irinotecan and Temozolomide in Combination With Existing High Dose Alkylator Based… Newly Diagnosed Ewing Sarcoma Active, Not Recruiting
NCT02436707 Novel Combination Therapy in the Treatment of Relapsed and Refractory Aggressive B-Cell… Lymphoma Active, Not Recruiting
NCT03821610 A Comparison of Reduced Dose Total Body Irradiation (TBI) and Cyclophosphamide With… Acute Lymphoblastic Leukemia Active, Not Recruiting
NCT03849651 TCRαβ-depleted Progenitor Cell Graft With Additional Memory T-cell DLI, Plus Selected Use… Acute Lymphoblastic Leukemia (ALL) Active, Not Recruiting
Phase 1/2
NCT04224558 Stem Cell Transplantation in Crohn's Disease Crohn Disease Recruiting
NCT04959175 Phase I/II Study to Reduce Post-transplantation Cyclophosphamide Dosing for Older or… Hematologic Neoplasms Recruiting
NCT05436418 The Lowest Effective Dose of Post-Transplantation Cyclophosphamide in Combination With… Peripheral Blood Stem Cell Transplantation Recruiting
NCT03577431 Liver Transplantation With Tregs at MGH Liver Transplant Active, Not Recruiting
NCT03573700 Evaluation of CD19-Specific CAR Engineered Autologous T-Cells for Treatment of… Acute Lymphoblastic Leukemia, in Relapse Active, Not Recruiting
Phase 1
NCT06326463 CAR T-cell Therapy Directed to CD70 for Pediatric Patients With Hematological Malignancies Hematologic Malignancy Recruiting
NCT06834282 CER-1236 in Patients With Acute Myeloid Leukemia (AML), Myelodysplastic Syndrome (MDS)… AML Recruiting
NCT04318678 CD123-Directed T-Cell Therapy for Acute Myelogenous Leukemia (CATCHAML) AML/MDS Recruiting
NCT04897321 B7-H3-Specific Chimeric Antigen Receptor Autologous T-Cell Therapy for Pediatric Patients… Pediatric Solid Tumor Recruiting
NCT06777979 CD19-CD22-Bispecific Chimeric Antigen Receptor (CAR) T Cell Therapy for Pediatric… Acute Lymphoblastic Leukemia Recruiting
NCT07257419 CD45RA-depleted CD19-CAR T Cell Consolidation After TCRαβ+/CD19 B Cell-depleted… Relapsed Pediatric ALL Recruiting
Sponsors Running Mesna Trials
Disease Areas
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