| Detected | Trial | Change |
|---|---|---|
| 2026-06-12 | NCT07328425 Clinical Study in Adult and Young Adult Patients With Advanced Desmoplastic Small Round… |
Trial sites expanded: 1 -> 5 locations |
| 2026-05-21 | NCT06801834 Study of Sacituzumab Govitecan Versus Standard of Care in Participants With Previously… |
Trial sites expanded: 205 -> 210 locations |
| 2026-05-19 | NCT07155174 A Study to Evaluate the Optimal Dose, Adverse Events and Change in Disease Activity of… |
Trial sites expanded: 34 -> 49 locations |
| 2026-05-16 | NCT06088290 Study of Lurbinectedin in Combination With Doxorubicin Versus Doxorubicin Alone as… |
overall status: "Recruiting" → "Active Not Recruiting" |
| 2026-05-14 | NCT05153239 Clinical Trial of Lurbinectedin as Single-agent or in Combination With Irinotecan Versus… |
Trial completed |
| 2026-05-14 | NCT07155174 A Study to Evaluate the Optimal Dose, Adverse Events and Change in Disease Activity of… |
Trial sites reduced: 42 -> 34 locations |
| First Posted | Trial | Phase | Status |
|---|---|---|---|
| 2026-06-11 | NCT07640932 Lurbinectedin Plus Paclitaxel Versus Paclitaxel in Patients With Previously Treated Small… | Phase 2 | Not Yet Recruiting |
| NCT ID | Title | Condition | Status |
|---|---|---|---|
| Phase 3 | |||
| NCT06801834 | Study of Sacituzumab Govitecan Versus Standard of Care in Participants With Previously… | Extensive Stage Small Cell Lung Cancer (ES-SCLC) | Recruiting |
| NCT06203210 | A Study of Ifinatamab Deruxtecan Versus Treatment of Physician's Choice in Subjects With… | Small Cell Lung Cancer | Recruiting |
| NCT05740566 | Study Comparing Tarlatamab With Standard of Care Chemotherapy in Relapsed Small Cell Lung… | Small Cell Lung Cancer (SCLC) | Active, Not Recruiting |
| NCT07365241 | A Study to Evaluate Adverse Events and Change in Disease Activity of Intravenous ABBV-706… | Small Cell Lung Cancer | Not Yet Recruiting |
| NCT06088290 | Study of Lurbinectedin in Combination With Doxorubicin Versus Doxorubicin Alone as… | Leiomyosarcoma | Active, Not Recruiting |
| NCT05091567 | A Phase III, Open-Label Study of Maintenance Lurbinectedin in Combination With… | Small-Cell Lung Cancer | Active, Not Recruiting |
| Phase 2 | |||
| NCT05578326 | Study of Trilaciclib and Lurbinectidin | Lung Cancer | Recruiting |
| NCT05800587 | Dose Attenuated Chemotherapy in Compromised Patients With Lung Cancer | Lung Cancer | Recruiting |
| NCT06228066 | Lurbinectedin With or Without Avelumab in Small Cell Carcinoma of the Bladder (LASER) | Small Cell Carcinoma of the Bladder | Recruiting |
| NCT06497530 | Maintenance Lurbinectedin in Combination With Serplulimab for Patients With ES-SCLC | Extensive-Stage Small Cell Lung Cancer | Recruiting |
| NCT07155174 | A Study to Evaluate the Optimal Dose, Adverse Events and Change in Disease Activity of… | Small Cell Lung Cancer | Recruiting |
| NCT07328425 | Clinical Study in Adult and Young Adult Patients With Advanced Desmoplastic Small Round… | Desmoplastic Small Round Cell Tumor | Recruiting |
| NCT04607954 | Durvalumab and Lurbinectedin for the Treatment of Relapsed or Refractory Small Cell Lung… | Platinum-Resistant Lung Small Cell Carcinoma | Active, Not Recruiting |
| NCT07459634 | A Study of Lurbinectedin in Combination With Durvalumab for the Treatment of Participants… | Extensive-stage Small-cell Lung Cancer | Not Yet Recruiting |
| NCT07640932 | Lurbinectedin Plus Paclitaxel Versus Paclitaxel in Patients With Previously Treated Small… | Carcinoma, Small Cell Lung | Not Yet Recruiting |
| Phase 1/2 | |||
| NCT05734066 | Study of Lurbinectedin Monotherapy in Pediatric and Young Adult Participants With… | Refractory Ewing Sarcoma | Recruiting |
| NCT06681220 | Biomarker Directed Trial of Temozolomide and Stenoparib in Relapsed SCLC | Relapsed Small Cell Lung Cancer | Recruiting |
| NCT05918640 | Lurbinectedin in FET-Fused Tumors | Ewing Sarcoma | Recruiting |
| NCT04802174 | Lurbinectedin With Berzosertib, an ATR Kinase Inhibitor in Small Cell Cancers and… | SCLC | Active, Not Recruiting |
| NCT05099666 | Lurbinectedin + Doxorubicin In Leiomyosarcoma | Advanced Soft-tissue Sarcoma | Active, Not Recruiting |
| Phase 1 | |||
| NCT05636111 | Phase 1b of Lurbinectedin in Combination With Weekly Paclitaxel and Bevacizumab in… | Ovarian Cancer | Recruiting |