Drug Pipeline

Hydroxyurea Clinical Trials

Data updated daily from ClinicalTrials.gov — last refresh 2026-06-12
23
Active Studies
11
Recruiting
5
Phase 3
10
Top Sponsors
3
Changes, 30 Days
What Changed in the Last 30 Days
DetectedTrialChange
2026-05-29 NCT03312400
Low-Dose Danazol for the Treatment of Telomere Related Diseases
overall status: "Recruiting" → "Active Not Recruiting"
2026-05-29 NCT03312400
Low-Dose Danazol for the Treatment of Telomere Related Diseases
Enrollment reduced: 40 -> 18 participants
2026-05-16 NCT03312400
Low-Dose Danazol for the Treatment of Telomere Related Diseases
date change Primary completion pushed: 2026-04-29 -> 2027-04-29
New Trial Filings, Last 30 Days
First PostedTrialPhaseStatus
2026-06-01 NCT07616154 Haploidentical Donor Hematopoietic Cell Transplant for Sickle Cell Disease Phase 2 Not Yet Recruiting
Active Studies by Phase
Phase 4
1
Phase 3
4
Phase 2/3
1
Phase 2
6
Phase 1/2
3
Phase 1
4
Early Phase 1
1
Not specified
3
Active Trials
NCT IDTitleConditionStatus
Phase 4
NCT06526117 Stroke Prevention in Nigeria 2 Trial Sickle Cell Disease Recruiting
Phase 3
NCT06093672 Study on Efficacy and Safety of Givinostat Versus Hydroxyurea in Patients With… Polycythemia Vera Recruiting
NCT04116502 MITHRIDATE: Ruxolitinib Versus Hydroxycarbamide or Interferon as First Line Therapy in… Polycythemia Vera Recruiting
NCT06456346 Bomedemstat vs Hydroxyurea for Essential Thrombocythemia (MK-3543-007) Essential Thrombocythemia Recruiting
NCT03165734 A Phase 3 Study of Pacritinib in Patients With Primary Myelofibrosis, Post Polycythemia… Primary Myelofibrosis Active, Not Recruiting
Phase 2/3
NCT03373968 Givinostat in Duchenne's Muscular Dystrophy Long-term Safety and Tolerability Study Duchenne Muscular Dystrophy Recruiting
Phase 2
NCT07033598 Pacritinib vs. Hydroxyurea in Advanced Proliferative Chronic Myelomonocytic Leukemia Leukemia, Myelomonocytic, Chronic Recruiting
NCT06930352 Ziftomenib for the Treatment of Patients With NPM1 Mutated or KMT2A Rearranged Acute… Acute Myeloid Leukemia Not Yet Recruiting
NCT07507760 Oral Decitabine Plus Ivosidenib as First Line for Older/Unfit Adult AML Patients Acute Myeloid Leukemia With Gene Mutations Not Yet Recruiting
NCT06171217 Realizing Effectiveness Across Continents With Hydroxyurea Sickle Cell Disease Active, Not Recruiting
NCT07616154 Haploidentical Donor Hematopoietic Cell Transplant for Sickle Cell Disease Sickle Cell Disease Not Yet Recruiting
NCT03312400 Low-Dose Danazol for the Treatment of Telomere Related Diseases Telomere Disease Active, Not Recruiting
Phase 1/2
NCT03500731 Lung and Bone Marrow Transplantation for Lung and Bone Marrow Failure Idiopathic Pulmonary Fibrosis Recruiting
NCT05357482 Addition of JSP191 (C-kit Antibody) to Nonmyeloablative Hematopoietic Cell… Sickle Cell Anemia Active, Not Recruiting
NCT03077542 Nonmyeloablative Haploidentical Peripheral Blood Mobilized Hematopoietic Precursor Cell… Sickle Cell Disease Active, Not Recruiting
Phase 1
NCT05526924 Dosing Study of Radiation Combined With Tislelizumab and Pamiparib in Patients With… Head and Neck Cancer Recruiting
NCT07190833 A Phase 1 Study of OTS-412 (Recombinant Oncolytic Vaccinia Virus) in Treatment-refractory… Treatment-Refractory Solid Tumors Recruiting
NCT06871410 Genetically Engineered Cells (CD83 CAR T Cells) for the Treatment of Relapsed or… Recurrent Acute Myeloid Leukemia Recruiting
NCT07170592 A Phase 1 Study of OTS-412 (Recombinant Oncolytic Vaccinia Virus) in Treatment-refractory… Treatment-Refractory Solid Tumors Not Yet Recruiting
Early Phase 1
NCT05662098 Alternative Dosing And Prevention of Transfusions (ADAPT) Sickle Cell Disease Active, Not Recruiting
Not specified
NCT03511118 Pharmacokinetics and Safety of Commonly Used Drugs in Lactating Women and Breastfed… Lactating Women on Select DOI Recruiting
NCT04217356 Study of Stem Cell Transplant vs. Non-Transplant Therapies in High-Risk Myelofibrosis Myelofibrosis Active, Not Recruiting
NCT07543289 Hydroxyurea Optimisation in Sickle Cell Disease Sickle Cell Disease Not Yet Recruiting
Sponsors Running Hydroxyurea Trials
Disease Areas
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