Drug Pipeline

Guselkumab Clinical Trials

Data updated daily from ClinicalTrials.gov — last refresh 2026-06-12
97
Active Studies
56
Recruiting
36
Phase 3
10
Top Sponsors
25
Changes, 30 Days
What Changed in the Last 30 Days
DetectedTrialChange
2026-06-12 NCT06663332
A Long-term Extension (LTE) Study of Guselkumab in Pediatric Participants
Trial sites expanded: 42 -> 47 locations
2026-06-12 NCT06663332
A Long-term Extension (LTE) Study of Guselkumab in Pediatric Participants
date change Completion pushed: 2031-12-12 -> 2032-02-25
2026-06-12 NCT05076175
A Study Investigating Oral Ozanimod (RPC1063) in Pediatric Participants With Moderate to…
date change Primary completion pushed: 2026-05-22 -> 2032-07-12
2026-06-12 NCT05076175
A Study Investigating Oral Ozanimod (RPC1063) in Pediatric Participants With Moderate to…
date change Completion pushed: 2031-08-14 -> 2032-07-12
2026-06-11 NCT07486921
Etrasimod as Prevention of Pouchitis
Recruitment opened
2026-06-09 NCT07577856
A Study of JNJ-78934804 in Participants With Moderately to Severely Active Ulcerative…
Recruitment opened
2026-06-09 NCT07577856
A Study of JNJ-78934804 in Participants With Moderately to Severely Active Ulcerative…
Trial sites expanded: 0 -> 6 locations
2026-06-09 NCT07577843
A Study of JNJ-78934804 in Participants With Moderately to Severely Active Crohn's Disease
Recruitment opened
2026-06-09 NCT07577843
A Study of JNJ-78934804 in Participants With Moderately to Severely Active Crohn's Disease
Trial sites expanded: 0 -> 5 locations
2026-06-06 NCT06260163
A Study of Guselkumab in Pediatric Participants With Moderately to Severely Active…
date change Primary completion moved earlier: 2028-05-22 -> 2027-02-10
2026-06-06 NCT06260163
A Study of Guselkumab in Pediatric Participants With Moderately to Severely Active…
date change Completion moved earlier: 2028-08-14 -> 2027-04-28
2026-06-06 NCT05083182
A Study of Ustekinumab or Guselkumab in Pediatric Participants With Active Juvenile…
date change Completion moved earlier: 2026-12-05 -> 2026-06-24
2026-06-06 NCT07499232
A Study of Guselkumab Versus Risankizumab in Participants With Moderately to Severely…
Trial sites expanded: 11 -> 30 locations
2026-06-04 NCT04338204
Observational Study To Assess The Effectiveness and Treatment Adherence Of Tofacitinib of…
Trial completed
2026-06-04 NCT04338204
Observational Study To Assess The Effectiveness and Treatment Adherence Of Tofacitinib of…
Enrollment reduced: 120 -> 102 participants
2026-06-04 NCT04338204
Observational Study To Assess The Effectiveness and Treatment Adherence Of Tofacitinib of…
date change Primary completion moved earlier: 2026-03-30 -> 2025-09-30
2026-06-04 NCT04338204
Observational Study To Assess The Effectiveness and Treatment Adherence Of Tofacitinib of…
date change Completion moved earlier: 2026-03-30 -> 2025-09-30
2026-06-03 NCT04624230
Evaluation of Oral Tofacitinib in Children Aged 2 to 17 Years Old Suffering From Moderate…
Trial sites reduced: 73 -> 68 locations
2026-06-02 NCT06654882
Trial of Sequential Medications AfteR TNFi Failure in Juvenile Idiopathic Arthritis
date change Primary completion pushed: 2026-06 -> 2026-12
2026-05-28 NCT07116967
Long-Term Safety Study of Deucravacitinib Versus Ustekinumab in Participants With…
Trial sites expanded: 357 -> 363 locations
Showing 20 of 25 changes detected in the last 30 days.
New Trial Filings, Last 30 Days
First PostedTrialPhaseStatus
2026-06-01 NCT07616687 Optimal Care With Guselkumab in Crohn's Disease / OPTIM Study A Prospective Open Label… Phase 4 Not Yet Recruiting
2026-05-22 NCT07602517 Guselkumab for Overlap Inflammatory Bowel Disease and Spondyloarthritis Not Yet Recruiting
2026-05-20 NCT07598643 Modulation of the Immune System in Down Syndrome for Improved Outcomes and… Phase 2 Recruiting
Active Studies by Phase
Phase 4
18
Phase 3
30
Phase 2/3
6
Phase 2
15
Phase 1/2
1
Phase 1
2
Not specified
25
Active Trials — top 25 of 97
NCT IDTitleConditionStatus
Phase 4
NCT07303686 De-escalation of Ustekinumab Therapy in Patients With Crohn's Disease and Ulcerative… Crohn Disease (CD) Recruiting
NCT06520397 Efficacy and Safety of Dual-targeted Therapy With Upadacitinib and Ustekinumab Versus… Crohn Disease Recruiting
NCT06045754 A Study of Vedolizumab Intravenous (IV) and Adalimumab or Vedolizumab and Ustekinumab in… Crohn's Disease Recruiting
NCT06095128 A Study of Vedolizumab With Tofacitinib in Adults With Ulcerative Colitis (UC) Ulcerative Colitis Recruiting
NCT05004727 Multi-Center PAMPA Study Psoriasis Recruiting
NCT05270733 Development of Predictive Psoriasis Response Endotypes Using Single Cell Transcriptomics Psoriasis Recruiting
NCT07554820 Major Adverse Cardiovascular Events (MACE) in Rheumatoid Arthritis Patient With Moderate… Rheumatoid Arthritis Recruiting
NCT06964113 A Study of Filgotinib 200 mg in Korean Participants With Moderately to Severely Active… Ulcerative Colitis Recruiting
NCT05169593 Prevention of Postoperative Endoscopic Recurrence With Endoscopy-driven Versus Systematic… Crohn Disease Recruiting
NCT06916390 GUselkumAb inteRvention and DIet evaluAtioN for Pouchitis Pouchitis Recruiting
NCT05858632 Immune Spatial Features of Guselkumab Cutaneous Response Psoriasis of Scalp Recruiting
NCT07141004 A Study of Guselkumab Administered Subcutaneously in Treatment of Indian Participants… Arthritis, Psoriatic Recruiting
NCT07310095 A Study to Evaluate the Efficacy of Guselkumab in Chinese Participants With Crohn's… Crohn Disease Recruiting
NCT07406204 Tofacitinib vs Methotrexate for Severe Alopecia Areata (TOFA-MTX-AA) Alopecia Areata Not Yet Recruiting
NCT04645355 Guselkumab Immunogenetics Psoriasis Guttate Active, Not Recruiting
NCT07616687 Optimal Care With Guselkumab in Crohn's Disease / OPTIM Study A Prospective Open Label… Crohn Disease (CD) Not Yet Recruiting
NCT07352566 Utilization of a Microdevice for Psoriasis and Atopic Dermatitis Psoriasis Not Yet Recruiting
NCT04929210 A Study of Guselkumab Administered Subcutaneously in Bio-naive Participants With Active… Arthritis, Psoriatic Active, Not Recruiting
Phase 3
NCT06865417 A Study Evaluating the Effects of Filgotinib in Children and Teenagers With Ulcerative… Ulcerative Colitis Recruiting
NCT04871191 Study of Salvage Therapy to Treat Patients With Granulomatosis With Polyangiitis Granulomatosis With Polyangiitis Recruiting
NCT03936361 Statins In Intracerbral Hemorrhage Intracerebral Hemorrhage Recruiting
NCT07553182 OLE Study With Filgotinib in JIA Juvenile Idiopathic Arthritis (JIA) Recruiting
NCT06408259 Study to Evaluate the Effectiveness and Safety of Ozanimod Compared to Fingolimod in… Multiple Sclerosis, Relapsing-Remitting Recruiting
NCT06425549 A Study to Evaluate the Efficacy and Safety of Bimekizumab Compared to Ustekinumab in… Moderate to Severe Plaque Psoriasis Recruiting
NCT07116967 Long-Term Safety Study of Deucravacitinib Versus Ustekinumab in Participants With… Plaque Psoriasis Recruiting
Sponsors Running Guselkumab Trials
Disease Areas
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