Disease landscape

Psoriasis clinical trials

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297 active trials 147 recruiting 51 Phase 3 177 sponsors 37 changes in 30 days

Data updated daily from ClinicalTrials.gov, last refresh 2026-08-28

What changed in the last 30 days showing 30 of 37 changes on 19 trials

2026-08-11
Trial terminated
Trial terminated: Sponsor decision
Enrollment reduced: 250 → 65 participants
Primary completion moved earlier: 2026-02-28 → 2025-12-16
Completion moved earlier: 2026-03 → 2025-12-16
NCT06380907 A Phase 2 Study of ZL-1102 in Patients With Chronic Plaque Psoriasis · Zai Lab (Hong Kong), Ltd. · Phase 2
2026-08-04
Trial terminated
Trial terminated: Due to the company's strategic adjustment in product portfolio, this study has been voluntarily terminated.
Primary completion moved earlier: 2026-12 → 2026-07-30
Completion moved earlier: 2027-07 → 2026-07-30
NCT07314060 A Clinical Trial of TQH2929 Injection in Patients With Acute Flare-up of Generalized… · Chia Tai Tianqing Pharmaceutical Group Co., Ltd. · Phase 2
2026-08-22
Primary completion pushed: 2026-08-28 → 2026-12-31
NCT06382051 Modifying PEST for Psoriatic Arthritis Screening · Novartis Pharmaceuticals
2026-08-05
Primary completion pushed: 2026-07 → 2027-01
Completion pushed: 2026-12 → 2027-12
NCT05981118 Comparison of Post-Inflammatory Pigment Alteration After Psoriasis Treatment (PIPA… · Wake Forest University Health Sciences · Phase 2/3
2026-08-05
Primary completion pushed: 2026-07 → 2027-01
Completion pushed: 2026-12 → 2027-07
NCT04058652 Use of Transcutaneous Electrical Nerve Stimulation for Reducing Biologic Injection Site… · Wake Forest University Health Sciences
2026-08-01
Primary endpoint(s) modified
NCT07736586 A Study of HL40626S Tablets in Healthy Adults · HighsLab Therapeutics Inc. · Phase 1
2026-08-04
Sponsor changed: Boehringer Ingelheim → LEO Pharma
NCT03886246 Effisayil™ ON: A Study to Test Long-term Treatment With Spesolimab in People With… · LEO Pharma · Phase 2
2026-08-04
Sponsor changed: Boehringer Ingelheim → LEO Pharma
NCT06013969 A Study to Test Whether Spesolimab Helps People With Generalized Pustular Psoriasis (GPP)… · LEO Pharma · Phase 4
2026-08-04
Sponsor changed: Highslab Therapeutics, Inc. → HighsLab Therapeutics Inc.
NCT07736586 A Study of HL40626S Tablets in Healthy Adults · HighsLab Therapeutics Inc. · Phase 1
2026-08-21
Recruitment opened
NCT07719530 Phase II Clinical Trial of SHR-1139 Injection in Patients With Psoriasis · Guangdong Hengrui Pharmaceutical Co., Ltd · Phase 2
2026-08-28
Trial status changed: Enrolling by Invitation → Recruiting
NCT02707341 The CorEvitas Psoriasis (PSO) Registry · CorEvitas
2026-08-18
Enrollment closed, study ongoing
NCT07290569 Dose Ranging Study of ORKA-001 in Patients With Moderate-to-Severe Plaque Psoriasis · Oruka Therapeutics, Inc. · Phase 2
2026-08-08
Enrollment closed, study ongoing
Trial sites reduced: 50 → 42 locations
NCT06425549 A Study to Evaluate the Efficacy and Safety of Bimekizumab Compared to Ustekinumab in… · UCB Biopharma SRL · Phase 3
2026-08-01
Trial completed
NCT04123795 A Study to Evaluate the Pharmacokinetics, Safety, and Effectiveness of Certolizumab Pegol… · UCB Biopharma SRL · Phase 3
2026-07-31
Trial completed
NCT06323356 A Study of TAK-279 in Adult Participants With Generalized Pustular Psoriasis or… · Takeda · Phase 3
2026-08-09
Sponsor changed: Second Affiliated Hospital, School of Medicine, Zhejiang University → Second Affiliated Hospital, Zhejiang University, School of Medicine
NCT07532486 A Study to Evaluate Comparative Efficacy and Safety of Guselkumab in High-dose and… · Second Affiliated Hospital, School of Medicine, Zhejiang University
2026-08-09
Sponsor changed: Second Affiliated Hospital, School of Medicine, Zhejiang University → Second Affiliated Hospital, Zhejiang University, School of Medicine
NCT06811558 Ixekizumab Versus Secukizumab in Over 70-year-old Patients with Psoriasis · Second Affiliated Hospital, School of Medicine, Zhejiang University
2026-08-09
Sponsor changed: Second Affiliated Hospital, School of Medicine, Zhejiang University → Second Affiliated Hospital, Zhejiang University, School of Medicine
NCT06794671 A Basket Trial of Vunakizumab in Inflammatory Skin Diseases · Second Affiliated Hospital, School of Medicine, Zhejiang University
2026-08-09
Sponsor changed: Second Affiliated Hospital, School of Medicine, Zhejiang University → Second Affiliated Hospital, Zhejiang University, School of Medicine
NCT05503875 Immunoclassification of Psoriasis: a Strategy for Precision Medicine · Second Affiliated Hospital, School of Medicine, Zhejiang University
2026-08-09
Sponsor changed: Second Affiliated Hospital, School of Medicine, Zhejiang University → Second Affiliated Hospital, Zhejiang University, School of Medicine
NCT04465838 Chinese Psoriasis Real World Evidence Research · Second Affiliated Hospital, School of Medicine, Zhejiang University

New sponsor entrants, last 90 days sponsors with their first trial in this area

First postedTrialSponsorPhase
2026-08-05 NCT07746479 A Study to Evaluate the Efficacy and Safety of LZM012 ( Psoriasis ) Livzon Pharmaceutical Group Inc. new Phase 3
2026-08-05 NCT07746583 A Study of Guselkumab Given After Ustekinumab in Participants With Moderate to Severe… Janssen-Cilag Kft. new
2026-07-30 NCT07736651 Anti Inflammatory Diet With Physical Therapy on Psoriasis Mahmoud Usama Mahmoud Ahmed new
2026-07-30 NCT07736586 A Study of HL40626S Tablets in Healthy Adults Highslab Therapeutics, Inc. new Phase 1
2026-07-29 NCT07733089 A Trial to Understand How Safe and Well Tolerated ZP9830 is and How it Works in People… Zealand Pharma new Phase 1
2026-07-28 NCT07730619 To Explore the Influencing Factors and Solutions for Patients With Plaque Psoriasis… First Affiliated Hospital Xi'an Jiaotong University new
2026-07-24 NCT07725822 An Open Label Trial to Evaluate Efficacy and Safety of Roflumilast 0.3% Cream for Chronic… Modern Research Associates, PLLC new Phase 4
2026-07-16 NCT07707141 Safety and Efficacy of HPP737 in Adult Patients With Plaque Psoriasis Newsoara Biopharma Co., Ltd. new Phase 2
2026-07-16 NCT07709169 Psoriasis and Its Impact on Quality of Life Among Psoriatic Patients Tanta University new
2026-07-09 NCT07693595 Nailfold Capillaroscopic Changes in Psoriasis Al-Azhar University new

Active trials by phase

Early Phase 1
5
Phase 1
17
Phase 1/2
4
Phase 2
29
Phase 2/3
5
Phase 3
46
Phase 4
36
Not charted: 155 active trials with no phase listed on ClinicalTrials.gov (typically behavioural, device, procedure and observational studies).

Active trials top 25 of 297

NCT IDTitleSponsorStatusUpdated
Phase 4
NCT05390515 Psoriatic Immune Response to Tildrakizumab University of California, San Francisco Recruiting 2026-06-04
NCT05858632 Immune Spatial Features of Guselkumab Cutaneous Response University of California, San Francisco Recruiting 2026-06-04
NCT05858645 Correction of Psoriatic T Cell Signatures by Deucravacitinib University of California, San Francisco Recruiting 2026-06-04
NCT06857942 A Study to Investigate the Effectiveness of Tirzepatide (LY3298176) Following Initiation… Eli Lilly and Company Recruiting 2026-06-03
NCT07432815 Treatment of Psoriasis With Depression and/or Anxiety With Methotrexate vs Combined… Cairo University Recruiting 2026-05-05
NCT05270733 Development of Predictive Psoriasis Response Endotypes Using Single Cell Transcriptomics University Hospitals Cleveland Medical Center Recruiting 2026-04-02
NCT05004727 Multi-Center PAMPA Study NYU Langone Health Recruiting 2026-03-30
NCT06398106 Proactive TDM Versus Standard Use of Biologics in Psoriasis University Hospital, Ghent Recruiting 2026-03-04
NCT07401992 Effects of Semaglutide on Clinical Outcomes and Metabolic Inflammation in Psoriasis Hospital Universitario Dr. Jose E. Gonzalez Recruiting 2026-02-11
NCT07149792 A Multi-center RCT Clinical Trial on Personalized Precision Medicine for Patients With… Taichung Veterans General Hospital Recruiting 2025-09-02
NCT03987763 A Safety and Pharmacokinetics Study of IDP-122 Lotion in Pediatric Participants With… Bausch Health Americas, Inc. Recruiting 2025-08-27
NCT06974474 Potential Role of Guselkumab in Modulating PAIN Perception and Related Gene Pathways: a… Fondazione Policlinico Universitario Campus Bio-Medico Recruiting 2025-05-16
NCT04537689 Outcomes With Treatment and Withdraw of Ixekizumab in Patients With Plaque Psoriasis Singapore General Hospital Recruiting 2022-11-25
NCT04372277 Taltz in Combination With Enstilar for Psoriasis Psoriasis Treatment Center of Central New Jersey Recruiting 2020-05-04
NCT04119102 Duobrii in Combination With Biologics Psoriasis Treatment Center of Central New Jersey Recruiting 2020-04-30
NCT04347473 ILUMYA in Combination With HALOG Ointment 0.1% for Plaque Psoriasis. Psoriasis Treatment Center of Central New Jersey Recruiting 2020-04-15
NCT03827876 Enstilar in Combination With Enbrel or Humira for Plaque Psoriasis Psoriasis Treatment Center of Central New Jersey Recruiting 2019-02-04
NCT07744191 A Clinical Trial of Antiplatelets in Psoriasis NYU Langone Health Not Yet Recruiting 2026-08-05
NCT06013969 A Study to Test Whether Spesolimab Helps People With Generalized Pustular Psoriasis (GPP)… LEO Pharma Active, Not Recruiting 2026-08-03
NCT07654751 A Study to Assess Concentration of TREMFYA in Breast Milk of Lactating Women Who Are… Janssen Research & Development, LLC Not Yet Recruiting 2026-07-31
NCT07725822 An Open Label Trial to Evaluate Efficacy and Safety of Roflumilast 0.3% Cream for Chronic… Modern Research Associates, PLLC Not Yet Recruiting 2026-07-28
NCT07713212 Combined Fractional CO₂ Laser and Topical Corticosteroid Versus Topical Corticosteroid… Cairo University Not Yet Recruiting 2026-07-20
NCT07487831 The Impact of Salt Intake on Sodium in the Skin and Inflammatory Skin Disease University of California, San Francisco Not Yet Recruiting 2026-06-09
NCT07635043 Efficacy of Topical Tapinarof Versus Betamethasone in the Treatment of Plaque Psoriasis Pakistan Institute of Medical Sciences Not Yet Recruiting 2026-06-09
NCT07352566 Utilization of a Microdevice for Psoriasis and Atopic Dermatitis University of California, San Francisco Not Yet Recruiting 2026-06-03
See all 297 active Psoriasis trials with filters →

Top sponsors by active trials in this area

Bristol-Myers Squibb (15) · Janssen Research & Development, LLC (8) · Cairo University (6) · University of California, San Francisco (6) · AbbVie (5) · Assiut University (5) · Psoriasis Treatment Center of Central New Jersey (5) · Second Affiliated Hospital, School of Medicine, Zhejiang University (5) · Assistance Publique - Hôpitaux de Paris (4) · Bausch Health Americas, Inc. (4)

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