Drug Pipeline

Copanlisib Clinical Trials

Data updated daily from ClinicalTrials.gov — last refresh 2026-06-12
15
Active Studies
0
Recruiting
5
Top Sponsors
1
Changes, 30 Days
What Changed in the Last 30 Days
DetectedTrialChange
2026-05-28 NCT04345913
Testing the Addition of Copanlisib to Eribulin in Metastatic Triple Negative Breast Cancer		 date change Completion pushed: 2026-05-07 -> 2027-05-31
Active Studies by Phase
Phase 2
6
Phase 1/2
4
Phase 1
5
Active Trials
NCT IDTitleConditionStatus
Phase 2
NCT03789240 Response-Adapted Therapy With Copanlisib and Rituximab in Untreated Follicular Lymphoma Follicular Lymphoma Active, Not Recruiting
NCT05490771 Testing Copanlisib as a Potential Targeted Treatment in Cancers With PIK3CA Mutations… Advanced Lymphoma Active, Not Recruiting
NCT03474744 Copanlisib and Rituximab in Marginal Zone Lymphoma Patients Marginal Zone Lymphoma Active, Not Recruiting
NCT06360588 Testing Copanlisib as Potentially Targeting Treatment in Cancers With PTEN Loss (MATCH… Malignant Solid Neoplasm Active, Not Recruiting
NCT06400238 Testing Copanlisib as Potentially Targeting Treatment in Cancers With PTEN Expression… Advanced Lymphoma Active, Not Recruiting
NCT02465060 Targeted Therapy Directed by Genetic Testing in Treating Patients With Advanced… Advanced Lymphoma Active, Not Recruiting
Phase 1/2
NCT04572763 Copanlisib Plus Venetoclax in R/R DLBCL Diffuse Large B Cell Lymphoma Active, Not Recruiting
NCT04939272 Copanlisib and Venetoclax for the Treatment of Relapsed or Refractory Mantle Cell Lymphoma Recurrent Mantle Cell Lymphoma Active, Not Recruiting
NCT04317105 Testing the Addition of an Anti-cancer Drug, Copanlisib, to the Usual Immunotherapy… Advanced Malignant Solid Neoplasm Active, Not Recruiting
NCT04345913 Testing the Addition of Copanlisib to Eribulin in Metastatic Triple Negative Breast Cancer Anatomic Stage III Breast Cancer AJCC v8 Active, Not Recruiting
Phase 1
NCT03884998 Copanlisib and Nivolumab in Treating Patients With Richter's Transformation or… Chronic Lymphocytic Leukemia Active, Not Recruiting
NCT03586661 Niraparib and Copanlisib in Treating Patients With Recurrent Endometrial, Ovarian… Deleterious BRCA1 Gene Mutation Active, Not Recruiting
NCT03502733 Testing the Combination of Copanlisib, Nivolumab and Ipilimumab in Patients With Advanced… Lymphoma Active, Not Recruiting
NCT03842228 Testing the Combination of the Anti-cancer Drugs Copanlisib, Olaparib, and MEDI4736… Advanced Malignant Solid Neoplasm Active, Not Recruiting
NCT03939897 Testing the Addition of Copanlisib to Usual Treatment (Fulvestrant and Abemaciclib) in… Anatomic Stage IV Breast Cancer AJCC v8 Active, Not Recruiting
Sponsors Running Copanlisib Trials
National Cancer Institute (NCI) (10) City of Hope Medical Center (2) Christian Buske (1) M.D. Anderson Cancer Center (1) Dana-Farber Cancer Institute (1)
Disease Areas
Breast Cancer (3) Multiple Myeloma (3) Ovarian Cancer (2) Endometrial Cancer (2) Non-Hodgkin Lymphoma (2) Follicular Lymphoma (2) DLBCL (2) Lung Cancer (1) Prostate Cancer (1) Pancreatic Cancer (1)
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