11

Active Studies

6

Recruiting

10

Top Sponsors

1

Changes, 30 Days

What Changed in the Last 30 Days

Detected	Trial	Change
2026-06-06	NCT03011671 Study of Acetazolamide With Temozolomide in Adults With Newly Diagnosed or Recurrent…	date change Primary completion pushed: 2025-06-26 -> 2026-12

New Trial Filings, Last 30 Days

First Posted	Trial	Phase	Status
2026-05-18	NCT07593612 TACTIC-HF: Sequential Diuretic Strategies in Ambulatory Worsening Heart Failure	Phase 4	Not Yet Recruiting

Active Studies by Phase

Phase 4

2

Phase 2

3

Phase 1/2

1

Phase 1

2

Early Phase 1

1

Not specified

2

Active Trials

NCT ID	Title	Condition	Status
Phase 4
NCT07101250	Preoperative Acetazolamide	Post Operative Pain	Recruiting
NCT07593612	TACTIC-HF: Sequential Diuretic Strategies in Ambulatory Worsening Heart Failure	Acute Heart Failure (AHF)	Not Yet Recruiting
Phase 2
NCT07372040	Add-on Diuretics in Acute Decompensated Heart Failure	Acute Decompensated Heart Failure	Recruiting
NCT05804084	Patient-centered and Neurocognitive Outcomes With Acetazolamide for Sleep Apnea	Obstructive Sleep Apnea	Recruiting
NCT06776432	Safety and Efficacy Study of Sivopixant, Acetazolamide and SASS-001 in Sleep Apnea	Sleep Apnea	Active, Not Recruiting
Phase 1/2
NCT04887792	Acetazolamide for Treatment Resistant Schizophrenia	Schizophrenia	Recruiting
Phase 1
NCT05470283	Phase I, Open-Label, Study of Tumor Infiltrating Lymphocytes Engineered With Membrane…	Tumor	Active, Not Recruiting
NCT03011671	Study of Acetazolamide With Temozolomide in Adults With Newly Diagnosed or Recurrent…	Malignant Glioma of Brain	Active, Not Recruiting
Early Phase 1
NCT07517068	The Role of Acetazolamide in Mitigating Inflammation and Innate Immune Activation at High…	Hypoxemia	Active, Not Recruiting
Not specified
NCT06285760	Effect of Acetazolamide on Diuresis and Natriuresis in Patients With Acute Heart Failure…	Heart Failure	Recruiting
NCT06945848	Venous Stenting Evaluation in Patients With Intracranial Hypertension Under Long-term…	Idiopathic Intracranial Hypertension (IIH)	Recruiting

Sponsors Running Acetazolamide Trials

University of Chicago (1) Vishwajit Nimgaonkar, MD PhD (1) M.D. Anderson Cancer Center (1) University of California, San Diego (1) Puerta de Hierro University Hospital (1) Shionogi (1) University Hospital, Montpellier (1) Prisma Health-Upstate (1) Tanta University (1) University of California, Riverside (1)

Disease Areas

Heart Failure (3) Glioma (1) Schizophrenia (1) Melanoma (1) Hypertension (1)

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Acetazolamide Clinical Trials