Clinical Trial

Preoperative Acetazolamide

Recruiting Phase 4
View on ClinicalTrials.gov →
Record status
This record was last updated February 20, 2026 (before its estimated August 1, 2026 completion). Its status may not reflect the trial's current state.
Summary
The goal of this randomized study looks at whether giving patients a medicine called acetazolamide (also called Diamox) before they have laparoscopic hysterectomy may decrease postoperative pain. Researchers will compare acetazolamide to a placebo or inactive drug, to see if acetazolamide helps the pain that may occur after surgery from the gas used in the abdomen during the laparoscopic procedure. Patients will be asked to rate their pain before surgery and after surgery through 24 hours.
Protocol Amendment History 2 amendments
This ClinicalTrials.gov record has been amended 2 times since 2025-07-31; most recent amendment 2026-02-18.
Status change: Not Yet Recruiting → Recruiting 2026-02-18
Trial Details
NCT Number NCT07101250
Lead Sponsor Prisma Health-Upstate
Conditions Post Operative Pain, Laparoscopic Hysterectomy, Referred Pain
Enrollment 100 participants
Start Date 2025-10-30
Primary Completion 2026-08-01 (estimated)
Study Completion 2026-11-01 (estimated)
Updated on ClinicalTrials.gov 2026-02-20