Disease landscape

Relapsed/Refractory Multiple Myeloma clinical trials

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116 active trials 63 recruiting 11 Phase 3 84 sponsors 11 changes in 30 days

Data updated daily from ClinicalTrials.gov, last refresh 2026-08-28

What changed in the last 30 days

2026-07-30
notable
Recruitment opened
NCT07609940 Adult Outpatient Linvoseltamab With Tocilizumab Prophylaxis to Mitigate the Risk of… · Regeneron Pharmaceuticals · Phase 4
2026-08-09
notable
Sponsor changed: Second Affiliated Hospital, School of Medicine, Zhejiang University → Second Affiliated Hospital, Zhejiang University, School of Medicine
NCT07359014 Novel CD19/BCMA Dual-Targeted CAR-T Cell Therapy for the Treatment of Relapsed/Refractory… · Second Affiliated Hospital, School of Medicine, Zhejiang University
2026-08-18
notable
Primary completion pushed: 2027-08-31 → 2027-10-01
Enrollment increased: 182 → 232 participants
Completion pushed: 2028-11-14 → 2029-01-25
NCT05850234 AZD0120 in Relapsed/Refractory Multiple Myeloma (DURGA-1) · AstraZeneca · Phase 1/2
2026-08-04
notable
Recruitment opened
Trial sites expanded: 0 → 3 locations
NCT07637578 A Study of Elranatamab Outpatient Administration in Patients With Relapsed/Refractory… · SCRI Development Innovations, LLC · Phase 2
2026-08-01
notable
Primary completion pushed: 2026-06-30 → 2026-08-30
NCT06285318 A Study of Clinical Outcomes in Patients With Relapsed/Refractory Multiple Myeloma (RRMM)… · Janssen-Cilag Ltd.
2026-08-07
minor
Trial sites expanded: 10 → 21 locations
NCT07284758 A Study to Evaluate the Efficacy of Cemsidomide + Dexamethasone in Participants With… · C4 Therapeutics, Inc. · Phase 2
2026-08-01
minor
Trial sites expanded: 1 → 4 locations
NCT07589634 A Study Evaluating the Prophylactic Use of Tocilizumab to Prevent Cytokine Release… · Janssen Research & Development, LLC · Phase 2
2026-08-02
minor
Trial status changed: Recruiting → Unknown
NCT05998928 A Clinical Study to Evaluate the Safety and Efficacy of BCMA-GPRC5D CAR-T in Patients… · Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Phase 2

Active trials by phase

Early Phase 1
18
Phase 1
28
Phase 1/2
18
Phase 2
20
Phase 3
11
Phase 4
1
Not charted: 20 active trials with no phase listed on ClinicalTrials.gov (typically behavioural, device, procedure and observational studies).

Active trials top 25 of 116

NCT IDTitleSponsorStatusUpdated
Phase 4
NCT07609940 Adult Outpatient Linvoseltamab With Tocilizumab Prophylaxis to Mitigate the Risk of… Regeneron Pharmaceuticals Recruiting 2026-08-20
Phase 3
NCT06508983 A Clinical Study Comparing SG301 Plus Pomalidomide and Dexamethasone to Placebo Plus… Hangzhou Sumgen Biotech Co., Ltd. Recruiting 2026-07-10
NCT07222761 A Study to Compare Linvoseltamab Monotherapy and Linvoseltamab + Carfilzomib Combination… Regeneron Pharmaceuticals Recruiting 2026-07-01
NCT05730036 A Trial to Learn How Well Linvoseltamab Works Compared to the Combination of Elotuzumab… Regeneron Pharmaceuticals Recruiting 2026-03-06
NCT06561854 Study Comparing Therapy for Advanced Relapsed/Refractory Multiple Myeloma With and… Assistance Publique - Hôpitaux de Paris Recruiting 2024-12-18
NCT04162210 Study of Single Agent Belantamab Mafodotin Versus Pomalidomide Plus Low-dose… GlaxoSmithKline Active, Not Recruiting 2026-07-01
NCT06956170 All Japanese Population: Belantamab Mafodotin Plus Pomalidomide and Dexamethasone (Pd)… GlaxoSmithKline Active, Not Recruiting 2026-06-12
NCT04484623 Belantamab Mafodotin Plus Pomalidomide and Dexamethasone (Pd) Versus Bortezomib Plus Pd… GlaxoSmithKline Active, Not Recruiting 2026-06-12
NCT07569757 Clinical Study of TQB2934 Injection in Relapsed/Refractory Multiple Myeloma Chia Tai Tianqing Pharmaceutical Group Co., Ltd. Not Yet Recruiting 2026-05-08
NCT06868667 Japan Expansion Cohort: Evaluation of Efficacy and Safety of Belantamab Mafodotin… GlaxoSmithKline Active, Not Recruiting 2026-04-23
NCT06868654 China Subpopulation: Evaluation of Efficacy and Safety of Belantamab Mafodotin… GlaxoSmithKline Active, Not Recruiting 2026-04-23
NCT04246047 Evaluation of Efficacy and Safety of Belantamab Mafodotin, Bortezomib and Dexamethasone… GlaxoSmithKline Active, Not Recruiting 2026-04-23
Phase 2
NCT07637578 A Study of Elranatamab Outpatient Administration in Patients With Relapsed/Refractory… SCRI Development Innovations, LLC Recruiting 2026-08-11
NCT07284758 A Study to Evaluate the Efficacy of Cemsidomide + Dexamethasone in Participants With… C4 Therapeutics, Inc. Recruiting 2026-08-06
NCT07589634 A Study Evaluating the Prophylactic Use of Tocilizumab to Prevent Cytokine Release… Janssen Research & Development, LLC Recruiting 2026-07-31
NCT07689058 CAR-T in Relapsed/Refractory Multiple Myeloma Dr. Zaineb Akram Recruiting 2026-07-08
NCT06421675 Outpatient and Intermittent Dosing of Elranatamab in Relapsed/Refractory Multiple Myeloma Ontario Clinical Oncology Group (OCOG) Recruiting 2026-06-17
NCT07509086 IL-15-Armored CAR-T Therapy in Relapsed or Refractory Multiple Myeloma and Plasma Cell… The First Hospital of Jilin University Recruiting 2026-04-03
NCT05896228 Iberdomide, Daratumumab, Carfilzomib, and Dexamethasone (Iber-KDd) in Patients With… Benjamin T Diamond, MD Recruiting 2026-03-11
NCT05530421 Selinexor, Venetoclax, and Dexamethasone (XVenD) in t(11;14)-Positive Relapsed/Refractory… University of Miami Recruiting 2026-02-23
NCT06711705 Elranatamab in Relapsed/Refractory Multiple Myeloma University of California, San Diego Recruiting 2026-02-20
NCT05922501 Isatuximab, Bela Maf, Pom, and Dex in Relapsed/Refractory Multiple Myeloma Massachusetts General Hospital Recruiting 2026-01-14
NCT06668792 An Open-Label Clinical Study of the Efficacy and Safety of BCD-248 in Patients With… Biocad Recruiting 2025-02-04
NCT06115135 A Study of Venetoclax in Combination With Isatuximab and Dexamethasone for… Oncotherapeutics Recruiting 2025-01-16
NCT06581640 Chimeric Antigen Receptor Modified T Cells Targeting BCMA for the Treatment of… The First Affiliated Hospital of Xiamen University Recruiting 2024-09-25

Top sponsors by active trials in this area

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