Clinical Trial

The Effects of Lumateperone on Obesity and Physiologic Aging and Their Association With Antidepressant Response in Bipolar Depression

Name: The Effects of Lumateperone on Obesity and Physiologic Aging and Their Association With Antidepressant Response in Bipolar Depression — clinical trial record (NCT07699445)
Creator: DataLookout
License: https://creativecommons.org/licenses/by/4.0/

Not Yet Recruiting Phase 4

View on ClinicalTrials.gov →

Summary

This research study examines how a medication called lumateperone may affect mood symptoms, and inflammation in adults with bipolar disorder over approximately 6 weeks. An MRI scan to calculate biological age of the brain will also be obtained at the start of the study.

Trial Details

NCT Number	NCT07699445
Lead Sponsor	Massachusetts General Hospital Collaborators: Johnson & Johnson K.K. Medical Company
Conditions	Bipolar Depression Depressed Phase, Obesity & Overweight
Enrollment	25 participants
Start Date	2026-07-31
Primary Completion	2028-01-31 (estimated)
Study Completion	2028-07-31 (estimated)
Updated on ClinicalTrials.gov	2026-07-13