Clinical Trial

Comparative Effectiveness of Oral Semaglutide vs Sitagliptin Among Individuals With Heart Failure With Preserved Ejection Fraction (STEP-HFpEF DM ORAL)

Active, Not Recruiting
View on ClinicalTrials.gov →
Summary
Investigators are building an empirical evidence base for real world data through large-scale emulation of randomized controlled trials. The investigators' goal is to understand for what types of clinical questions real world data analyses can be conducted with confidence and how to implement such studies.
Protocol Amendment History 2 changes
notable Primary completion pushed: 2026-05-30 -> 2026-06-30 2026-07-02
minor Completion pushed: 2026-05-30 -> 2026-06-30 2026-07-02
Trial Details
NCT Number NCT07390110
Lead Sponsor Brigham and Women's Hospital
Conditions Type 2 Diabetes, Heart Failure
Enrollment 25,664 participants
Start Date 2026-01-24
Primary Completion 2026-06-30 (estimated)
Study Completion 2026-06-30 (estimated)
Updated on ClinicalTrials.gov 2026-07-01